Active Clinical Trials

Clinical trials are at the heart of our work to bring innovative medicines to people with a particular disease or condition. Learn more about the active studies conducted by Novartis including opportunities to get involved.

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Study title Condition Phase Location

Safety and Efficacy of Fingolimod in Pediatric Patients With Multiple Sclerosis

Multiple Sclerosis Phase3 Germany
Mexico
Ukraine
United Kingdom
Spain
France
United States
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Study of Efficacy and Safety of Iptacopan in Participants With IC-MPGN

IC-MPGN Phase3 United States
Turkey
Spain
Italy
United Kingdom
Brazil
Germany
Switzerland
Argentina
Japan
Israel
Vietnam
France
Canada
India
Poland
Czechia
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Registry of Patients With a Diagnosis of Spinal Muscular Atrophy (SMA)

Spinal Muscular Atrophy (SMA) United States
Russian Federation
Japan
Portugal
Ireland
Greece
Taiwan
Korea, Republic of
Israel
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A NIS of Alpelisib in Combination With Fulvestrant in Postmenopausal Women, and Men, With HR+,HER2- , Locally Advanced or Metastatic Breast Cancer With a PIK3CA Mutation, After Disease Progression Following Endocrine Therapy as Monotherapy, in the Real-world Setting

Hormone Receptor Positive HER2 Negative Breast Cancer With a PIK3CA Mutation Spain
Italy

Secukinumab Drug Survival, Effectiveness and Tolerability in Pediatric Patients With Psoriasis

Moderate-to-severe Plaque Psoriasis Russian Federation

Study to Assess the Efficacy and Safety of Alpelisib Plus Fulvestrant in Participants With HR-postitive (HR+), HER2-negative, Advanced Breast Cancer After Treatment With a CDK4/6 Inhibitor and an Aromatase Inhibitor.

Breast Cancer Phase3 Spain
Denmark
Greece
Germany
Italy
France
Slovakia
Czechia
Belgium
Hungary
Poland
Canada
Portugal
Romania
Ireland
Finland
Bulgaria
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A Study to Investigate the Efficacy, Safety, and Tolerability of DFV890 and MAS825 for Inflammatory Marker Reduction in Adult Participants With Coronary Heart Disease and Clonal Hematopoiesis of Indeterminate Potential (CHIP)

Coronary Heart Disease, Clonal Hematopoiesis of Indeterminate Potential (CHIP) Phase2 Germany
Canada
United States

Study of Efficacy, Safety and Tolerability of DFV890 in Patients With Knee Osteoarthritis

Symptomatic Knee Osteoarthritis Phase2 United States
Germany
Czechia
Romania
Hungary
Argentina
Spain
Slovakia
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To Evaluate Efficacy, Safety, Tolerability and PK of Intravenous Cipargamin in Participants With Severe Plasmodium Falciparum Malaria

Severe Malaria Phase2 Côte D'Ivoire
Burkina Faso
Nigeria
Rwanda
Congo, The Democratic Republic of the
Gabon
India
Kenya
Uganda
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Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis (RMS)

Relapsing Multiple Sclerosis Phase3 United States
United Arab Emirates
Spain
Jordan
Belgium
Israel
Lebanon
China
Switzerland
Colombia
Slovakia
Argentina
Poland
India
Ireland
Austria
Guatemala
Saudi Arabia
Taiwan
Lithuania
Malaysia
Italy
Croatia
Bulgaria
Latvia
Netherlands
Chile
Hong Kong
Denmark
Georgia
United Kingdom
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