Active Clinical Trials

Clinical trials are at the heart of our work to bring innovative medicines to people with a particular disease or condition. Learn more about the active studies conducted by Novartis including opportunities to get involved.

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Study title Condition Phase Location

To Evaluate Efficacy, Safety, Tolerability and PK of Intravenous Cipargamin in Participants With Severe Plasmodium Falciparum Malaria

Severe Malaria Phase 2 Côte D'Ivoire
Burkina Faso
Nigeria
Rwanda
Congo, The Democratic Republic of the
Gabon
India
Kenya
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Effectiveness and Safety of Dabrafenib in Combination With Trametinib as Adjuvant Treatment for Chinese Patients With Stage III BRAF V600 Mutation-positive Melanoma After Complete Resection

Melanoma China

Rollover Study for Patients With Sickle Cell Disease Who Have Completed a Prior Novartis-Sponsored Crizanlizumab Study

Sickle Cell Disease Phase 4 Turkey
United States
Lebanon
Belgium
Colombia
France
Germany
Spain
Oman
Italy
Brazil
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Study to Evaluate the Efficacy, Safety and Tolerability of MAS825 in Patients With Monogenic IL-18 Driven Autoinflammatory Diseases, Including NLRC4-GOF, XIAP Deficiency, or CDC42 Mutations

NLRC4-GOF, AIFEC (Autoinflammation With Infantile Enterocolitis), XIAP Deficiency, CDC42 Mutations Phase 2 Italy
Czech Republic
United States
United Kingdom
Spain
Turkey
France
Japan
Canada
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Secukinumab Open Label Roll-over Extension Protocol

Autoimmunity, Inflammation Phase 4 United States
China
Poland
Colombia
Czech Republic
Mexico
Guatemala
Brazil
South Africa
Bulgaria
Spain
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Study Assessing the Efficacy, Safety and PK of Alpelisib (BYL719) in Pediatric and Adult Patients With PIK3CA-related Overgrowth Spectrum

PIK3CA-related Overgrowth Spectrum (PROS) Phase 2 United States
Switzerland
France
Germany
Spain
United Kingdom
Canada
Netherlands
Hong Kong
Italy
China
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Special Drug Use-results Surveillance of Tabrecta Tablets

Non-small Cell Lung Cancer Japan

A Rollover Extension Program (REP) to Evaluate the Long-term Safety and Tolerability of Open Label Iptacopan/LNP023 in Participants With Primary IgA Nephropathy

Primary IgA Nephropathy Phase 3 United States
Denmark
Australia
Israel
India
Thailand
China
Norway
Germany
Korea, Republic of
Argentina
Brazil
Belgium
Netherlands
Hong Kong
Turkey
Taiwan
Malaysia
Japan
United Kingdom
Italy
Canada
France
Czech Republic
Singapore
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Efficacy, Safety and Tolerability of KAF156 in Combination With Lumefantrine Solid Dispersion Formulation (LUM-SDF) in Pediatric Population With Uncomplicated Plasmodium Falciparum Malaria

Uncomplicated Plasmodium Falciparum Malaria Phase 2 Burkina Faso
Mali
Gabon

Safety and Efficacy Study of Fingolimod in Taiwanese Adults (≥ 20years) With Relapsing Remitting Multiple Sclerosis

Multiple Sclerosis Phase 4 Taiwan