Active Clinical Trials

Clinical trials are at the heart of our work to bring innovative medicines to people with a particular disease or condition. Learn more about the active studies conducted by Novartis including opportunities to get involved.

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Study title Condition Phase Location NCT ID

A Study to Investigate the Pharmacokinetics and Safety of Remibrutinib in Participants With Severe Renal Impairment Compared to Matched Healthy Participants.

Autoimmune and Chronic Inflammatory Diseases Phase1 United States

NIS PDC the Efficacy and Safety of Iptacopan in Adults in Routine Clinical Practice

Paroxysmal Nocturnal Hemoglobinuria Russia

Efficacy and Safety of Remibrutinib After Switching From Ocrelizumab in Participants Living With Relapsing Multiple Sclerosis.

Relapsing Multiple Sclerosis Phase3 Argentina
Australia
Canada
Denmark
France
Italy
Slovakia
South Africa
Spain
Switzerland
United States
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Pelacarsen Roll-over Extension Program

Atherosclerotic Cardiovascular Disease Phase3 United States

Long-term Follow up Local Registry Study of Kymriah in South Korea

B-Cell Acute Lymphoblastic Leukemia, Diffuse Large B-Cell Lymphoma, Follicular Lymphoma South Korea

Inclisiran Effectiveness in China: a Pragmatic Randomized Trial

Coronary Heart Disease Phase4 China

Open-label Extension Study of Zigakibart in Adults With IgA Nephropathy.

Kidney Diseases, Kidney Diseases, Chronic, Urological Diseases, Glomerulonephritis, Glomerular Disease, Glomerulonephritis, IGA, Glomerulopathy, Immunoglobulin Disease Phase3 Argentina
South Korea
United States

Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC

Prostate Cancer Phase3 Australia
China
Hong Kong
Japan
Singapore
Taiwan
United Kingdom
United States
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Study to Evaluate the Impact of Iptacopan on Top of SOC on Biopsy Changes in Kidneys of Adult Patients With IgAN

Glomerulonephritis, IGA, Immunoglobulin A Nephropathy Phase2 Israel
Malaysia
United States

A Study to Evaluate Efficacy of Remibrutinib Compared to Dupilumab at Early Timepoints in Adults With Chronic Spontaneous Urticaria Inadequately Controlled by Second Generation H1-antihistamines

Chronic Spontaneous Urticaria (CSU) Phase3 United States