Active Clinical Trials

Clinical trials are at the heart of our work to bring innovative medicines to people with a particular disease or condition. Learn more about the active studies conducted by Novartis including opportunities to get involved.

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Study title Condition Phase Location NCT ID

Phase 2a Study to Assess the Efficacy,Safety and Tolerability of GIA632 in Adult Participants With Moderate to Severe Atopic Dermatitis

 		Atopic Dermatitis Phase2 Bulgaria
Canada
Czechia
France
Germany
Malaysia
Poland
Singapore
United States
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 NCT07220577

A Phase II Trial to Evaluate the Clinical Efficacy, Safety and Tolerability of MAS825 in Pediatric and Adult Participants With Still's Disease

 		Still´s Disease Phase2 Canada
France
Germany
Italy
Netherlands
Spain
Turkey (Türkiye)
United States
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 NCT07203001

A Clinical Trial to Learn About the Effects of VHB937 in People With Early Alzheimer's Disease

 		Alzheimer's Disease Phase2 Australia
Canada
Czechia
France
Germany
Japan
Netherlands
Poland
South Korea
Sweden
United Kingdom
United States
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 NCT07094516

Phase I Study of [225Ac]Ac-ETN029 in Patients With Advanced DLL3-expressing Solid Tumors

 		Small Cell Lung Carcinoma, Large Cell Neuroendocrine Carcinoma of the Lung, Neuroendocrine Prostate Cancer, Gastroenteropancreatic Neuroendocrine Carcinoma Phase1 Canada
South Korea
United States 		NCT07006727

EPIK-P4: A Phase II Single-arm Study to Assess the Efficacy, Safety and Pharmacokinetics of Alpelisib (BYL719) in Pediatric and Adult Patients With PIK3CA-related Overgrowth Spectrum (PROS)

 		PIK3CA-related Overgrowth Spectrum (PROS) Phase2 Australia
Austria
Belgium
France
Germany
Italy
Spain
Switzerland
United States
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 NCT06997588

A First in Human Study to Assess the Safety, Tolerability, and Pharmacokinetics of EDK060 in Adults With CMT1A.

 		Charcot-Marie-Tooth Disease, Type 1A Phase1 Canada NCT07140614

An Open-label Dose Escalation and Expansion, Followed by a Phase II Study of Tulmimetostat (DZR123) and JSB462 (Luxdegalutamide) in Patients With Progressive Metastatic Castrate Resistant Prostate Cancer (mCRPC) (TulmiSTAR-01)

 		Progressive Metastatic Castrate Resistant Prostate Cancer Phase1, Phase2 Australia
Canada
China
Denmark
France
Italy
Malaysia
Poland
Singapore
Spain
United States
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 NCT07206056

Study of Efficacy and Safety of Ruxolitinib in Chinese Participants With Corticosteroid-refractory Chronic Graft vs. Host Disease

 		Graft vs. Host Disease, Chronic Graft vs. Host Disease, Corticosteroid-refractory Chronic Graft vs. Host Disease Phase4 China NCT06824103

RWE Non-Interventional Prospective Study of Ribociclib Effectiveness and Safety in Patients With HR+/HER2- Early Breast Cancer in Saudi Arabia

 		HR+/HER2- Early Breast Cancer Saudi Arabia NCT06797531

NIS PDC the Efficacy and Safety of Iptacopan in Adults in Routine Clinical Practice

 		Paroxysmal Nocturnal Hemoglobinuria Russia NCT07036718