Active Clinical Trials

Clinical trials are at the heart of our work to bring innovative medicines to people with a particular disease or condition. Learn more about the active studies conducted by Novartis including opportunities to get involved.

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Study title Condition Phase Location NCT ID

A Study to Evaluate the Pharmacodynamics of a Combination of QCZ484 and Inclisiran in Participants With Hypertension and Concomitant Hypercholesterolemia

Hypercholesterolaemia Phase2 United States

A Drug-drug Interaction Study to Evaluate the Effects of Pelabresib on the Pharmacokinetics of Repaglinide, Midazolam, and Combined Oral Contraceptive in Patients With Advanced Malignancies

Advanced Malignancies Phase1 France
Italy
Spain

Phase I Study of JFI447 [68Ga]Ga-DFC413 and Comparison to FFG233 [68Ga]Ga-NNS309 in Patients With Solid Tumors

Metastatic Pancreatic Ductal Adenocarcinoma (PDAC), Non-small Cell Lung Cancer (NSCLC), HR+/HER2- Ductal Breast Cancer (BC), HR+/HER2- Lobular Breast Cancer (BC), Triple Negative Breast Cancer (TNBC), Colorectal Cancer (CRC), Soft Tissue Sarcoma (STS) Phase1 Denmark
Japan

A Phase I Study of [68Ga]Ga-DWJ155 in Patients With Breast and Lung Cancers

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung Phase1 Netherlands

A Study of Ruxolitinib in Patients With Graft-Versus Host Disease

Graft-Versus-Host Disease Japan

Study of Efficacy and Safety of Secukinumab in Chinese Adult Patients With Moderate to Severe Hidradenitis Suppurativa

Hidradenitis Suppurativa (HS) Phase4 China

An Open-label Extension Safety and Efficacy Study of QCZ484 in Hypertensive Patients.

Hypertension (HTN) Phase2 Japan
Singapore
United States

A First-in-human Study to Investigate Single Doses of DCY636 in Healthy Volunteers and Multiple Doses in Participants With Moderate to Severe Atopic Dermatitis

Dermatitis, Atopic Phase1 Japan

Study of IEV407 as Single Agent or in Combination in Patients With Advanced HR+/HER2- Breast Cancer

Advanced HR+/HER2- Breast Cancer Phase1 Canada
France
Italy
Japan
Singapore
South Korea
United States
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A Study to Evaluate DJI136, a DLL3-targeted CAR-T Therapy

Extensive-stage Small Cell Lung Cancer (ES-SCLC) Phase1, Phase2 Australia
Singapore
South Korea
United States
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