Active Clinical Trials

Clinical trials are at the heart of our work to bring innovative medicines to people with a particular disease or condition. Learn more about the active studies conducted by Novartis including opportunities to get involved.

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Study title Condition Phase Location NCT ID

Pharmacokinetics and Safety Study of Pelabresib in Patients With Advanced Malignancies and Hepatic Impairment

Advanced Malignancies and Hepatic Impairment Phase1 France
Italy
Spain
United Kingdom
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A Study to Investigate the Safety and Tolerability of Oral INR731 Single Agent or in Combination With Androgen Receptor Pathway Inhibitor (ARPI) in Patients With Metastatic Prostate Cancer

Metastatic Castration-resistant Prostate Cancer (mCRPC) Phase1 Australia
Japan
United States

Remibrutinib Open Label Roll-over Post-trial Access Protocol

Indication of the Parent Protocol Phase3 Bulgaria
Canada
Czechia
France
Poland
South Korea
Spain
Vietnam
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A Study to Evaluate the Efficacy of NIO752 in Participants With Progressive Supranuclear Palsy

Progressive Supranuclear Palsy Richardson Syndrome (PSP-RS) Phase3 Australia
China
France
Germany
Italy
Japan
Netherlands
South Korea
Spain
United States
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A Study to Assess the Tolerability of Ianalumab (VAY736) With Investigator's Choice Thrombopoietin Receptor Agonist (IC TPO-RA) in Patients With Primary Immune Thrombocytopenia (ITP)

Primary Immune Thrombocytopenia (ITP), Primary Evans Syndrome (ES) Phase2 United States

Long-term Safety and Tolerability of Inclisiran in Participants With HeFH or HoFH Who Have Completed the Pediatric ORION-16, ORION-13, ORION-20, or ORION-19 Studies

Heterozygous or Homozygous Familial Hypercholesterolemia Phase3 Taiwan

Study to Determine the Efficacy and Safety of Asciminib in Pediatric Patients With Ph+ CML-CP

Chronic Myelogenous Leukemia, Leukemia, Myelogenous, Chronic, Philadelphia Chromosome Positive Phase2 Australia
Brazil
Canada
China
France
Germany
Italy
Japan
Netherlands
Poland
South Korea
Spain
United States
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Long Term Observational Study to Collect in a Real-world populatIon Data on the Treatment Pattern of Secukinumab in Adult Patients With Moderate to Severe HS Within the Italian Population

Hidradenitis Suppurativa Italy

REAL-CARE: Real-world Effectiveness of Iptacopan in Italian Patients With Paroxysmal Nocturnal Hemoglobinuria

Paroxysmal Nocturnal Hemoglobinuria (PNH) Italy

A Phase 3 Study of Pelabresib (DAK539) and Ruxolitinib in Myelofibrosis (MF)

Primary Myelofibrosis (PMF), Post-polycythemia Vera Myelofibrosis (PPV-MF), Post-essential Thrombocythemia Myelofibrosis (PET-MF) Phase3 Argentina
Australia
China
India
Italy
Japan
Malaysia
South Korea
Switzerland
Taiwan
Turkey (Türkiye)
United States
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