Active Clinical Trials

Clinical trials are at the heart of our work to bring innovative medicines to people with a particular disease or condition. Learn more about the active studies conducted by Novartis including opportunities to get involved.

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Study title Condition Phase Location

Evaluation of HU-resistance in Adult Patients With Polycythemia Vera Who Meet PV-AIM Predictors

 		Polycythemia Vera Phase 4 Germany

A Phase II Study of AAA617 Alone and AAA617 in Combination With ARPI in Patients With PSMA PET Scan Positive CRPC

 		Prostatic Neoplasm Phase 2 Spain
Poland
Canada
Czech Republic
Korea, Republic of
Singapore
United States
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Efficacy, Safety and Tolerability of KLU156 in Adults and Children ≥ 5 kg Body Weight With Uncomplicated P. Falciparum Malaria

 		Uncomplicated Plasmodium Falciparum Malaria Phase 3 Congo, The Democratic Republic of the

Study of HRO761 Alone or in Combination in Cancer Patients With Specific DNA Alterations Called Microsatellite Instability or Mismatch Repair Deficiency.

 		MSIhi or dMMR Advanced Unresectable or Metastatic Solid Tumors, Including Colorectal Cancers Phase 1 United States
Spain
France
Belgium
Germany
Japan
Korea, Republic of
Singapore
Taiwan
Israel
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Phase IIIb Study of Ribociclib + ET in Early Breast Cancer

 		Early Breast Cancer Phase 3 Australia

Ofatumumab in Portuguese Multiple Sclerosis Patients - an Observational Study

 		Relapsing Multiple Sclerosis Portugal

Long-Term Safety of Lutetium (177Lu) Vipivotide Tetraxetan in Participants With Prostate Cancer

 		Prostate Cancer Phase 4 United States

An Open-label, Study to Assess Safety, Efficacy and Cellular Kinetics of YTB323 in Severe, Refractory Systemic Lupus Erythematosus

 		Systemic Lupus Erythematosus, Lupus Nephritis Phase 1, Phase 2 Spain
Switzerland
Australia
Germany
France
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Early Versus Late Ofatumumab (Kesimpta®) Use in Austrian RMS-Patients Over 2 Years

 		Relapsing Multiple Sclerosis Austria

Phase III Study of Efficacy and Safety of Secukinumab Versus Placebo, in Combination With Glucocorticoid Taper Regimen, in Patients With Polymyalgia Rheumatica (PMR)

 		Polymyalgia Rheumatica Phase 3 United States
France
Netherlands
Turkey
Japan
Lebanon
Germany
Spain
United Kingdom
Colombia
Switzerland
Italy
Czech Republic
Hungary
Poland
South Africa
Argentina
Denmark
Mexico
Australia
Israel
Belgium
Canada
Brazil
Chile
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