Active Clinical Trials

Clinical trials are at the heart of our work to bring innovative medicines to people with a particular disease or condition. Learn more about the active studies conducted by Novartis including opportunities to get involved.

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Study title Condition Phase Location NCT ID

An Open-label Study to Assess the Safety, Efficacy, and Cellular Kinetics of YTB323 in Relapsing Multiple Sclerosis

 		Relapsing Multiple Sclerosis Phase1, Phase2 Australia
France
Germany
Italy
Spain
Switzerland
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 NCT06617793

ELIOS - Investigational Biomarkers to Track Disease Modification in Active RRMS

 		Relapsing Remitting Multiple Sclerosis (RRMS) Phase4 Canada NCT06733922

A Study of Radiation Dosimetry, Safety, and Tolerability of Extended Lutetium (177Lu) Vipivotide Tetraxetan Treatment in Chemo-naïve Adults With Metastatic Castration-resistant Prostate Cancer: RADIOpharmaceutical DOSimetry Evaluation (RADIODOSE) Study

 		Metastatic Castration-Resistant Prostate Cancer Phase1 Germany
Netherlands
Spain
Switzerland
United Kingdom
United States
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 NCT06531499

Phase 2 Study of Rapcabtagene Autoleucel in Myositis

 		Idiopathic Inflammatory Myopathies Phase2 France
Germany
Israel
Italy
Japan
Singapore
Spain
Taiwan
United States
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 NCT06665256

Specified Drug-use Surveillance of Fabhalta Capsules

 		Paroxysmal Nocturnal Hemoglobinuria Japan NCT06606314

A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)

 		Healthy Volunteers, Pulmonary Arterial Hypertension Phase1, Phase2 Australia
Latvia
Portugal
Romania
United States
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 NCT06649110

An Ascending Dose Study of PIT565 in Participants With Systemic Lupus Erythematosus (SLE).

 		Systemic Lupus Erythematosus, SLE Phase1 China
Germany
Hungary
Netherlands
Spain
Switzerland
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 NCT06335979

A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE)

 		Sickle Cell Disease Phase3 Colombia
United States 		NCT06439082

Registry of Patients With a Diagnosis of Spinal Muscular Atrophy (SMA)

 		Spinal Muscular Atrophy (SMA) Greece
Ireland
Israel
Poland
Portugal
Romania
Russia
South Korea
Taiwan
United States
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 NCT04174157

Efficacy and Safety of Iptacopan (LNP023) in Adult Patients With Atypical Hemolytic Uremic Syndrome Naive to Complement Inhibitor Therapy

 		Atypical Hemolytic Uremic Syndrome Phase3 Austria
Brazil
China
Czechia
Greece
India
Japan
Slovakia
Slovenia
South Korea
Taiwan
United Kingdom
United States
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 NCT04889430