Active Clinical Trials

Clinical trials are at the heart of our work to bring innovative medicines to people with a particular disease or condition. Learn more about the active studies conducted by Novartis including opportunities to get involved.

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Study title Condition Phase Location

Kesimpta (Ofatumumab) Pregnancy Registry

Multiple Sclerosis, Pregnancy United States

Study to Assess the Safety of Alpelisib Plus Fulvestrant, in Men and Post-menopausal Women With HR-positive, HER2-negative, Advanced Breast Cancer (aBC) With PIK3CA Mutation, Whose Disease Progressed on or After Endocrine Treatment

Advanced Breast Cancer Phase 4 India

Single Arm, Open Label Trial With Iptacopan Treatment for 24 Weeks, in Patients on Stable Regimen of Anti-C5 Who Switch to Iptacopan.

Paroxysmal Nocturnal Hemoglobinuria Phase 3 Germany
United States
Italy
Turkey
Spain
United Kingdom
France
Korea, Republic of
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Regulatory Post-Marketing Surveillance of Xolair® for Chronic Rhinosinusitis With Nasal Polyps

Chronic Rhinosinusitis With Nasal Polyps Korea, Republic of

Phase 3 Study to Evaluate Ianalumab on Top of Standard-of-care Therapy in Patients With Systemic Lupus Erythematosus (SIRIUS-SLE 2)

Systemic Lupus Erythematosus Phase 3 United States
Germany
India
Italy
France
Colombia
Romania
Argentina
Chile
Korea, Republic of
Mexico
Malaysia
Taiwan
United Kingdom
Australia
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A Study of Secukinumab to Evaluate Maintenance of Response in Participants With Non-radiographic Axial Spondyloarthritis Who Achieved Remission

Non-radiographic Axial Spondyloarthritis Phase 4 Turkey
Netherlands
Italy
Germany
Thailand
Colombia
Brazil
Poland
Romania
Belgium
Hungary
France
Mexico
Israel
Vietnam
Malaysia
Philippines
Czech Republic
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A PMS of Jakavi® in Patients With Steroid-Refractory Graft-versus-Host Disease (SR-GvHD) in Korea

Graft-versus-Host Disease Korea, Republic of

A Study to Investigate the Safety, Tolerability and Preliminary Efficacy of NGI226 Microparticles in Patients With Achilles Tendinopathy

Achilles Tendinopathy Phase 2 United States
Germany
France
United Kingdom
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A 24-week Study Evaluating the Effectiveness and Safety of Lucentis® 0.2mg in Retinopathy of Prematurity Participants in China

Retinopathy of Prematurity China

Study of Efficacy and Safety of AIN457/Secukinumab in Patients With Rotator Cuff Tendinopathy

Tendinopathy Phase 3 Germany