Active Clinical Trials

Clinical trials are at the heart of our work to bring innovative medicines to people with a particular disease or condition. Learn more about the active studies conducted by Novartis including opportunities to get involved.

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Study title Condition Phase Location NCT ID

A Drug-drug Interaction Study to Evaluate the Effects of Pelabresib on the Pharmacokinetics of Repaglinide, Midazolam, and Combined Oral Contraceptive in Patients With Advanced Malignancies

 		Advanced Malignancies Phase1 Italy
Spain 		NCT07340190

Phase I Study of JFI447 [68Ga]Ga-DFC413 and Comparison to FFG233 [68Ga]Ga-NNS309 in Patients With Solid Tumors

 		Metastatic Pancreatic Ductal Adenocarcinoma (PDAC), Non-small Cell Lung Cancer (NSCLC), HR+/HER2- Ductal Breast Cancer (BC), HR+/HER2- Lobular Breast Cancer (BC), Triple Negative Breast Cancer (TNBC), Colorectal Cancer (CRC), Soft Tissue Sarcoma (STS) Phase1 Japan NCT07630961

Rollover Study for Participants Who Have Been Treated With and Are Continuing to Benefit From Opnurasib as a Single Agent or in Combination With Other Study Treatments

 		Locally Advanced or Metastatic KRAS G12C-mutated Non-small Cell Lung Cancer, Advanced Solid Tumors Harboring the KRAS G12C Mutation Phase1, Phase2 South Korea NCT07468071

A Phase I Study of [68Ga]Ga-DWJ155 in Patients With Breast and Lung Cancers

 		Breast Neoplasms, Carcinoma, Non-Small-Cell Lung Phase1 Netherlands NCT07117214

[177Lu]Lu-NeoB in Combination With Ribociclib and Fulvestrant in Participants With ER+, HER2- and GRPR+ Advanced Breast Cancer

 		Breast Cancer Phase1 Poland
United States 		NCT05870579

A Study of Ruxolitinib in Patients With Graft-Versus Host Disease

 		Graft-Versus-Host Disease Japan NCT07594587

Study of Efficacy and Safety of Secukinumab in Chinese Adult Patients With Moderate to Severe Hidradenitis Suppurativa

 		Hidradenitis Suppurativa (HS) Phase4 China NCT07489573

An Open-label Extension Safety and Efficacy Study of QCZ484 in Hypertensive Patients.

 		Hypertension (HTN) Phase2 Singapore
United States 		NCT07543120

A First-in-human Study to Investigate Single Doses of DCY636 in Healthy Volunteers and Multiple Doses in Participants With Moderate to Severe Atopic Dermatitis

 		Dermatitis, Atopic Phase1 Japan NCT07604324

Study of IEV407 as Single Agent or in Combination in Patients With Advanced HR+/HER2- Breast Cancer

 		Advanced HR+/HER2- Breast Cancer Phase1 Singapore
United States 		NCT07604571