Active Clinical Trials

Clinical trials are at the heart of our work to bring innovative medicines to people with a particular disease or condition. Learn more about the active studies conducted by Novartis including opportunities to get involved.

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Study title Condition Phase Location

A Study to Investigate LDL-cholesterol Lowering With Inclisiran Compared to Bempedoic Acid in Patients With Atherosclerotic Cardiovascular Disease.

Hypercholesterolemia Phase4 Germany

Study of PIT565 in Relapsed and/or Refractory B-cell Malignancies

B-cell Non-Hodgkin Lymphoma (B-NHL), B-cell Acute Lymphoblastic Leukemia (B-ALL) Phase1 Belgium
France
Israel
Italy
Japan
Singapore
Spain
United States
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A Study of Ribociclib in Combination With Hormonal Therapy in HR+/HER2- Advanced or Metastatic Breast Cancer

Breast Cancer Jordan

Phase 2b Study to Investigate the Safety and Efficacy of TIN816 in Sepsis-associated Acute Kidney Injury (SA-AKI)

Acute Kidney Injury Due to Sepsis Phase2 Australia
Austria
Belgium
Brazil
Canada
China
France
Germany
Italy
Japan
Spain
Thailand
Turkey
United Kingdom
United States
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Study to Assess the Efficacy and Safety of Alpelisib Plus Fulvestrant in Participants With HR-postitive (HR+), HER2-negative, Advanced Breast Cancer After Treatment With a CDK4/6 Inhibitor and an Aromatase Inhibitor.

Breast Cancer Phase3 Belgium
Bulgaria
Canada
Czechia
Denmark
Finland
France
Germany
Greece
Hungary
Ireland
Italy
Poland
Portugal
Romania
Slovakia
Spain
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Evaluation of HU-resistance in Adult Patients With Polycythemia Vera Who Meet PV-AIM Predictors

Polycythemia Vera Phase4 Germany

Phase 2 Study Evaluating Rapcabtagene Autoleucel in Participants With Diffuse Cutaneous Systemic Sclerosis

Scleroderma, Diffuse Phase2 Singapore
United States

A Phase III Study to Investigate Efficacy, Safety and Tolerability of Iptacopan Compared With Placebo in Participants Aged 18 to 75 Years With gMG.

Generalized Myasthenia Gravis Phase3 Greece
Italy
Japan
Poland
Portugal
Spain
United Kingdom
United States
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Study of Efficacy and Safety of LNP023 in Participants With Active Lupus Nephritis Class III-IV, +/- V

Lupus Nephritis Phase2 Brazil
China
France
Germany
Hong Kong
Hungary
India
Israel
Malaysia
Mexico
Portugal
Puerto Rico
Singapore
Spain
Turkey
United States
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A 24-week Study Evaluating the Effectiveness and Safety of Lucentis® 0.2mg in Retinopathy of Prematurity Participants in China

Retinopathy of Prematurity China