Active Clinical Trials

Clinical trials are at the heart of our work to bring innovative medicines to people with a particular disease or condition. Learn more about the active studies conducted by Novartis including opportunities to get involved.

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Study title Condition Phase Location NCT ID

Rollover Study for Participants Who Have Been Treated With and Are Continuing to Benefit From Opnurasib as a Single Agent or in Combination With Other Study Treatments

 		Locally Advanced or Metastatic KRAS G12C-mutated Non-small Cell Lung Cancer, Advanced Solid Tumors Harboring the KRAS G12C Mutation Phase1, Phase2 Belgium
Canada
China
Denmark
France
Italy
Spain
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 NCT07468071

A Phase I Study of [68Ga]Ga-DWJ155 in Patients With Breast and Lung Cancers

 		Breast Neoplasms, Carcinoma, Non-Small-Cell Lung Phase1 Netherlands NCT07117214

A Study of Ruxolitinib in Patients With Graft-Versus Host Disease

 		Graft-Versus-Host Disease Japan NCT07594587

Study of Efficacy and Safety of Secukinumab in Chinese Adult Patients With Moderate to Severe Hidradenitis Suppurativa

 		Hidradenitis Suppurativa (HS) Phase4 China NCT07489573

An Open-label Extension Safety and Efficacy Study of QCZ484 in Hypertensive Patients.

 		Hypertension (HTN) Phase2 Japan
Singapore
United States 		NCT07543120

A First-in-human Study to Investigate Single Doses of DCY636 in Healthy Volunteers and Multiple Doses in Participants With Moderate to Severe Atopic Dermatitis

 		Dermatitis, Atopic Phase1 Japan NCT07604324

Study of IEV407 as Single Agent or in Combination in Patients With Advanced HR+/HER2- Breast Cancer

 		Advanced HR+/HER2- Breast Cancer Phase1 Canada
Japan
Singapore
South Korea
United States
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 NCT07604571

A Study to Evaluate DJI136, a DLL3-targeted CAR-T Therapy

 		Extensive-stage Small Cell Lung Cancer (ES-SCLC) Phase1, Phase2 Singapore
United States 		NCT07564401

A Study on the Use of Canakinumab Among Familial Mediterranean Fever and Still's Disease Patients

 		Familial Mediterranean Fever, Still Disease, Systemic Juvenile Idiopathic Arthritis, Adult-Onset Still Disease Switzerland NCT07517250

A Study on the Tolerability, Safety and Effectiveness of Asciminib in Patients With Philadelphia Chromosome-positive Chronic Myeloid Leukemia in the Chronic Phase in Germany

 		Leukemia, Chronic Myeloid Germany NCT07549516