We work across multiple therapeutic areas to uncover biological insights to drive the discovery and development of the next generation of medicines. From the inception of a therapeutic through early clinical development, our disease area teams collaborate across scientific disciplines and organizations in support of our mission to improve and extend peoples’ lives.

Cardiovascular & Metabolic Diseases

Heart muscle cells.

Our Cardiovascular & Metabolic Diseases team works to better understand the root causes of cardiovascular and metabolic diseases, and discover and develop therapies against relevant targets.

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Diseases of Aging and Regenerative Medicine

Knee cartilage.

The DARe group is focused on elucidating and targeting the molecular mechanisms underlying diseases of aging and developing potential regenerative pharmacological interventions that restore tissue integrity and function.



Exploratory Disease Research (DAx)

Liver cells

DAx catalyzes and drives transformative therapies for emerging, high-potential indications. Current research focuses on liver and kidney diseases, and fibrosis.

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Global Health

Novartis Institute for tropical diseases

The Global Health Disease Area (DA) is discovering novel medicines to help control and, ideally, eliminate diseases impacting some of the world’s most vulnerable and underserved populations.

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Multiplex immunofluorescence staining illustrating intradermal sheets of migrating stratified squamous epithelium and associated inflammatory response in Hidradenitis suppurativa. Image provided by Lab Wieczorek.

The Immunology group is developing transformative therapies, including small molecules and biotherapeutics, that target the root cause of disease by modulating the immune system to restore health.

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Astrocytes in a brain organoid.

Our neuroscience research team works to discover transformative therapies that address the underlying cause of neurodegenerative, neurodevelopmental and neuropsychiatric diseases to dramatically improve the lives of patients.

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Breast cancer cells.

Our Oncology team is developing a robust portfolio of treatments that destroy tumors selectively and strip away their defenses.

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Mouse retina

The Ophthalmology research team is working to develop a diverse portfolio of compounds – small molecules, biologics and gene-based treatments – that protect and restore vision.

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