Study Description
This CML disease registry (ASC4REAL-2) aims to gather evidence on the tolerability, safety, effectiveness, and patient-reported outcomes (PRO) in real-world healthcare from patients with Ph+-CML-CP treated with TKIs approved for 1L and 2L, including prospective follow-up for 5 years identifying and describing long-term treatment outcomes.
Interventions
TKIs
Eligibility Criteria
Inclusion Criteria:
* 18 years or older at the time of Ph+-CML-CP diagnosis.
* Receiving TKI treatment (asciminib, bosutinib, dasatinib, imatinib, or nilotinib) in routine medical care either as initial therapy or after 1 prior TKI therapy.
* Receiving treatment at US and US territories (i.e., Puerto Rico) medical practice (e.g. community-based, office-based, hospital-based, academic).
* Signed informed consent form (ICF) prior to participation in the study including agreement to be tokenized so that the patient's anonymized RWD (EMRs and/or claims data) can be accessed.
Exclusion Criteria:
* Active participation in an interventional trial that may influence the management of their Ph+-CML-CP disease.
* Currently being treated with a CML TKI in 3L or beyond.
* Known presence of T315I mutation.
* Currently in TFR phase and are not on active CML TKI therapy.
* Previously received treatment with a prior stem cell transplant
* Pregnant or nursing (lactating) female.
Avera Cancer
Recruiting
Sioux Falls,South Dakota,57105,United States
Tiffani Kirkpatrick
MultiCare Health System Institute
Recruiting
Tacoma,Washington,98405,United States
Nehal Masood
Ali Dadla
Fred Hutchinson Cancer Research Center
Recruiting
Seattle,Washington,98109-1024,United States
Vivian Oehler
Baylor Scott and White Research
Recruiting
Temple,Texas,76502,United States
Lucas Wong
University of Alabama at Birmingham
Recruiting
Birmingham,Alabama,35233-0271,United States
Omer Jamy
Oregon Oncology Specialists Salem
Recruiting
Salem,Oregon,97301,United States
John Strother
Tri-County Hematology and Oncology Associates
Recruiting
Canton,Ohio,44718,United States
Norman Rafique
SUNY Upstate Medical University
Recruiting
Syracuse,New York,13210,United States
Gillian Kupakuwana-Suk
NY Cancer and Blood Specialists
Recruiting
East Setauket,New York,11733,United States
Adam Hines
Sacred Heart Medical Oncology
Recruiting
Pensacola,Florida,32504,United States
Dany El-Sayah
Stamford Hospital
Recruiting
Stamford,Connecticut,06902,United States
Joshua Dower
Lundquist Inst BioMed at Harbor
Recruiting
Torrance,California,90509-2910,United States
Sarah Elizabeth Tomassetti
Stockton Hematology Oncology Medical Group Inc
Recruiting
Stockton,California,95204,United States
Ravleen Grewal
Worldwide Contacts
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