Active Clinical Trials
Clinical trials are at the heart of our work to bring innovative medicines to people with a particular disease or condition. Learn more about the active studies conducted by Novartis including opportunities to get involved.
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| Study title | Condition | Phase | Location |
|---|---|---|---|
A Study to Investigate the Safety and Tolerability of Intravenous QEQ278 in Patients With Advanced Solid Tumors |
Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Esophageal Squamous Cell Carcinoma, Squamous Cell Carcinoma of Head and Neck | Phase 1 | United States Spain Belgium Germany Japan Italy France Singapore Taiwan View All |
A Study to Investigate Tolerability and Efficacy of Asciminib (Oral) Versus Nilotinib (Oral) in Adult Participants (≥18 Years of Age) With Newly Diagnosed Philadelphia Chromosome Positive Chronic Myelogenous Leukemia in Chronic Phase (Ph+ CML-CP) |
Philadelphia Chromosome-Positive Chronic Myeloid Leukemia | Phase 3 | United States Germany United Arab Emirates India Malaysia Jordan Turkey Greece Italy France Slovakia Czech Republic Romania Hungary Argentina Korea, Republic of Netherlands Switzerland United Kingdom Oman Bulgaria South Africa Singapore Canada View All |
Study of Efficacy and Safety of JDQ443 Single-agent as First-line Treatment for Patients With Locally Advanced or Metastatic KRAS G12C- Mutated Non-small Cell Lung Cancer With a PD-L1 Expression < 1% or a PD-L1 Expression ≥ 1% and an STK11 Co-mutation. |
Locally Advanced or Metastatic KRAS G12C-mutated NSCLC With a PD-L1 Expression <1% or a PD-L1 Expression ≥ 1% and an STK11 Co-mutation | Phase 2 | United States Turkey Malaysia Greece Thailand Spain Italy China Brazil Germany Bulgaria Netherlands France Argentina Austria India Portugal Hungary Belgium Singapore United Kingdom View All |
Study of Efficacy, Safety and Tolerability of Remibrutinib in Adult Participants With an Allergy to Peanuts |
Allergy, Peanut | Phase 2 | United States Spain |
Study of Efficacy and Safety of Ribociclib (LEE011) in Combination With Topotecan and Temozolomide (TOTEM) in Pediatric Patients With Relapsed or Refractory Neuroblastoma and Other Solid Tumors |
Neuroblastoma | Phase 1, Phase 2 | United States Spain Germany Italy Australia Singapore France View All |
A Phase I/II Study of DYP688 in Patients With Metastatic Uveal Melanoma and Other GNAQ/11 Mutant Melanomas |
Metastatic Uveal Melanoma | Phase 1, Phase 2 | United States Germany Netherlands Spain Australia France Switzerland View All |
Study Evaluating Effectiveness and Adherence of Inclisiran Plus Standard of Care (SoC) Lipid-lowering Therapy Compared to SoC in ASCVD |
Primary Hypercholesterolemia, Mixed Dyslipidemia | United Arab Emirates Switzerland United Kingdom Austria Israel Saudi Arabia Malaysia China View All |
|
Study of PIT565 in Relapsed and/or Refractory B-cell Malignancies |
B-cell Non-Hodgkin Lymphoma (B-NHL), B-cell Acute Lymphoblastic Leukemia (B-ALL) | Phase 1 | United States Spain Italy Belgium Japan France Singapore Israel View All |
Asciminib Monotherapy, With Dose Escalation, for 2nd and 1st Line Chronic Myelogenous Leukemia |
Chronic Myelogenous Leukemia - Chronic Phase | Phase 2 | United States |
Efficacy and Safety of Secukinumab in Patients With New Onset of Giant Cell Arteritis Who Are in Clinical Remission |
Giant Cell Arteritis | Phase 3 | Germany |