Active Clinical Trials

Clinical trials are at the heart of our work to bring innovative medicines to people with a particular disease or condition. Learn more about the active studies conducted by Novartis including opportunities to get involved.

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Study title Condition Phase Location

A Global Study of Midostaurin in Combination With Chemotherapy to Evaluate Safety, Efficacy and Pharmacokinetics in Newly Diagnosed Pediatric Patients With FLT3 Mutated AML

FLT3-mutated Acute Myeloid Leukemia Phase 2 Turkey
Jordan
Germany
Italy
Czech Republic
Poland
Slovenia
Korea, Republic of
Japan
Austria
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Study of Efficacy and Safety of Asciminib in Combination With Imatinib in Patients With Chronic Myeloid Leukemia in Chronic Phase (CML-CP)

CML, Chronic Myelogenous Leukemia, Leukemia, Myeloid Chronic, Hematologic Diseases Phase 2 United States
France
Czech Republic
United Kingdom
Spain
Canada
Taiwan
Austria
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Study of Dose Confirmation and Safety of Crizanlizumab in Pediatric Sickle Cell Disease Patients

Sickle Cell Disease (SCD) Phase 2 Turkey
United States
Spain
Lebanon
Germany
Belgium
Colombia
United Kingdom
Italy
Canada
Oman
India
France
Brazil
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Dabrafenib and/or Trametinib Rollover Study

Melanoma, Non Small Cell Lung Cancer, Solid Tumor, Rare Cancers, High Grade Glioma Phase 4 United States
Spain
Thailand

Dose Finding Study of TNO155 in Adult Patients With Advanced Solid Tumors

Advanced EGFRmutant NonSmallSellLungCancer (NSCLC),KRAS G12-mutant NSCLC,Esophageal SquamousCellCancer (SCC),Head/Neck SCC,Melanoma Phase 1 United States
Netherlands
Spain
Japan
Italy
Korea, Republic of
Singapore
Taiwan
Canada
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Study to Allow Patients Previously Participating in a Novartis Sponsored Trial to Continue Receiving Capmatinib Treatment as Single Agent or in Combination With Other Treatments or the Combination Treatment Alone

Advanced Solid Tumors Which Are cMET-dependent Phase 2 United States
Canada
Germany
Belgium
Italy
Korea, Republic of
Singapore
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Roll-over Study to Allow Access to Certinib (LDK378) for Patients Who Are on Ceritinib Treatment in a Novartis-sponsored Study

ALK Positive Malignancies Phase 4 Italy
Brazil
China
Russian Federation
Singapore
France
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CAR-T Long Term Follow Up (LTFU) Study

Long Term Safety of Patients Receiving CAR-T in an Eligible Clinical Trial or Managed Access Program Not Applicable United States
Spain
Germany
Australia
Japan
Denmark
Belgium
Canada
Finland
United Kingdom
Italy
Norway
France
Singapore
Taiwan
Austria
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CINC424A2X01B Rollover Protocol

Primary Myelofibrosis, Polycythemia Vera, Graft Versus Host Disease, Acute Myeloid Leukemia, Thalassemia Phase 4 Japan
Italy
Korea, Republic of

Safety and Efficacy of Fingolimod in Pediatric Patients With Multiple Sclerosis

Multiple Sclerosis Phase 3 Serbia
Romania
Ukraine
United Kingdom
Spain
France
Australia
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