Active Clinical Trials

Clinical trials are at the heart of our work to bring innovative medicines to people with a particular disease or condition. Learn more about the active studies conducted by Novartis including opportunities to get involved.

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Study title Condition Phase Location NCT ID

A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE)

Sickle Cell Disease Phase3 Brazil
Colombia
Kenya
Uganda
United States
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Registry of Patients With a Diagnosis of Spinal Muscular Atrophy (SMA)

Spinal Muscular Atrophy (SMA) Greece
Ireland
Israel
Poland
Portugal
Romania
Russia
South Korea
Taiwan
United States
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A Study to Evaluate the Efficacy and Safety of QMF149 (Indacaterol Acetate/Mometasone Furoate) Versus Budesonide in Children From 6 to Less Than 12 Years of Age With Asthma

Asthma Phase3 Argentina
Brazil
Bulgaria
Colombia
Greece
Guatemala
Hungary
Italy
Mexico
Panama
Portugal
Romania
South Africa
Spain
Vietnam
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Home Reported Outcomes in PNH

Paroxysmal Nocturnal Hemoglobinuria United States

Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Glycopyrronium (Bromide) in Children (6 to Less Than 12 Years) With Asthma

Asthma Phase2 Bulgaria
Colombia
Guatemala
Hungary
Poland
South Africa
Spain
United Kingdom
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A Study of 177Lu-FAP-2286 in Advanced Solid Tumors

Solid Tumor Phase1, Phase2 Australia
Canada
France
Italy
Spain
United States
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Phase 3 Extension Study to Evaluate Long-term Safety of Ianalumab in Participants With Systemic Lupus Erythematosus (SIRIUS-SLE Extension).

Systemic Lupus Erythematosus Phase3 Argentina
Australia
Brazil
Bulgaria
Canada
Chile
China
Colombia
Czechia
France
Germany
Guatemala
Hungary
India
Israel
Italy
Japan
Malaysia
Mexico
Poland
Portugal
Romania
South Africa
South Korea
Spain
Taiwan
Thailand
United States
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Evaluate Long-term Safety, Tolerability and Efficacy of Iptacopan in Study Participants With aHUS

Atypical Hemolytic Uremic Syndrome Phase3 Brazil
China
Czechia
India
Japan
Turkey (Türkiye)
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Kesimpta (Ofatumumab) Pregnancy Registry

Multiple Sclerosis, Pregnancy United States

Clinical Study To Further Evaluate The Efficacy Of Dabrafenib Plus Trametinib In Patients With Rare BRAF V600E Mutation-Positive Unresectable or Metastatic Solid Tumors

Rare Unresectable or Metastatic BRAF V600E Mutation-positive Solid Tumors United States