Last Update: Dec 11, 2025
Real-world Experience of Lutetium (177Lu) Vipivotide Tetraxetan in Metastatic Castration Resistant Prostate Cancer, an Observational, National, Multicenter, Prospective Cohort Study (PLU4REAL).
ClinicalTrials.gov Identifier:
NCT07093801
Novartis Reference Number:CAAA617A1IT01
See if you Pre-qualify
All compounds are either investigational or being studied for (a) new use(s). Efficacy and safety have not been established. There is no guarantee that they will become commercially available for the use(s) under investigation.

Study Description

This is a local prospective, multicenter, long-term, non-interventional study using primary data collection to describe the routine clinical practice of patients with mCRPC treated with lutetium (177Lu) vipivotide tetraxetan. The observation period will be from date of start of treatment up to a maximum of 18 months after end of treatment.

Metastatic Castration Resistant Prostate Cancer
Recruiting
300
Jul 30, 2025
Mar 30, 2029
Male
18 Years - 99 Years (Adult, Older Adult)

Eligibility Criteria

1. Adult patients diagnosed with mCRPC eligible for and prescribed with lutetium (177Lu) vipivotide tetraxetan by the treating physician (Multidisciplinary Team).
2. ≥ 18 years old at the time of enrollment.
3. Written informed consent must be obtained to participate to this study

In addition to the above-listed criteria, no other inclusion/exclusion criteria exist other than the requirements stated in the local Summary of Product Characteristics (SmPC) and in the "Scheda di Monitoraggio AIFA", e.g., contraindications.

Novartis Investigative Site

Recruiting

Palermo,PA,90146,Italy

Novartis Investigative Site

Recruiting

Napoli,80131,Italy

Novartis Investigative Site

Recruiting

Torino,TO,10128,Italy

Novartis Investigative Site

Recruiting

La Spezia,SP,19121,Italy

Novartis Investigative Site

Recruiting

Roma,RM,00189,Italy

Novartis Investigative Site

Recruiting

Roma,RM,00168,Italy

Novartis Investigative Site

Recruiting

Roma,RM,00152,Italy

Novartis Investigative Site

Recruiting

Reggio Emilia,RE,42123,Italy

Novartis Investigative Site

Recruiting

Rionero in Vulture,PZ,85028,Italy

Novartis Investigative Site

Recruiting

Pisa,PI,56126,Italy

Novartis Investigative Site

Recruiting

Perugia,PG,06129,Italy

Novartis Investigative Site

Recruiting

Brescia,BS,25123,Italy

Novartis Investigative Site

Recruiting

Rozzano,MI,20089,Italy

Novartis Investigative Site

Recruiting

Milan,MI,20162,Italy

Novartis Investigative Site

Recruiting

Milan,MI,20133,Italy

Novartis Investigative Site

Recruiting

Macerata,MC,62100,Italy

Novartis Investigative Site

Recruiting

Latina,LT,04100,Italy

Novartis Investigative Site

Recruiting

Genova,GE,16132,Italy

Novartis Investigative Site

Recruiting

Florence,FI,50134,Italy

Novartis Investigative Site

Recruiting

Cona,FE,44124,Italy

Novartis Investigative Site

Recruiting

Catania,CT,95123,Italy

Worldwide Contacts

If the location of your choosing does not feature any contact detail, please reach out using the information below.

Novartis Pharmaceuticals

+41613241111