We support complex, multi‑modality manufacturing and solve challenges across scale‑up, compliance, and global supply. Our partnership‑led approach combines expert people with proven execution to deliver reliable outcomes and regulatory confidence.
Proven Excellence, Built by People
Put your manufacturing challenges in our hands. We treat every client’s process as if it were our own—because you, and your patients, depend on it.
Our people are at the heart of what we do. From our people on the ground at our plants to our senior leadership, Novartis is committed to contract manufacturing long term. Our reputation is built on the results we deliver for our partners.
People First
Commitment at Every Level
Flexible Global Network
Results-driven execution in all manufacturing environments provides predictable outcomes and regulatory confidence.
Technologies Offering
Mammalian Drug Substance (DS)
Clinical to commercial GMP manufacturing at scale
Multiproduct mammalian cell culture manufacturing for monoclonal antibodies and other recombinant biologics, supporting programs from late clinical development through commercial supply.
Our integrated manufacturing model enables partners to select the optimal production scale for each lifecycle phase, while ensuring smooth tech transfer, process robustness, and supply reliability.
Key capabilities
- Mammalian cell culture drug substance manufacturing
- Scalable production volumes from 150L up to 15,000 L
- Options for Single Use, Stainless Steel and Hybrid set ups
- Extensive experience in fed batch, N-1 perfusion and continuous manufacturing
Microbial Drug Substance (DS)
Flexible GMP manufacturing within a single site
Efficient scale selection for biologic drug substance production within a single, integrated GMP site, supporting both clinical and commercial needs while minimizing operational complexity.
Key capabilities
- Scalable volumes: 150 L, 1.3 kL, 3 kL, 13 kL and 40kL
- Single-site manufacturing to support continuity and speed
- Proven operational expertise within Novartis’ microbial competence center
Small Molecules
Integrated API, drug product, and fill & finish capabilities
Novartis provides end-to-end contract manufacturing for oral solid dosage from active pharmaceutical ingredient (API) production through finished drug product and fill & finish. Our sites are equipped to manage complex processes, diverse dosage forms, and global supply requirements.
Key capabilities
- API manufacturing
- Oral solid dosage (OSD) forms
- Sterile and non-sterile injectables
- Integrated fill & finish services
- Expertise in Hot Melt Extrusion, nanomilling, wet milling
Cell & Gene (CGT) Viral Vectors
Advanced GMP manufacturing for complex modalities
Pioneer in advanced therapy manufacturing, offering GMP contract manufacturing for gene-based cell therapies and viral vectors. Our high‑tech facilities are designed to manage the unique challenges of advanced therapies, including complexity, variability, and regulatory rigor.
Key capabilities
- Gene‑modified cell therapy manufacturing (e.g. CAR‑T)
- Viral vector manufacturing (e.g. AAV, lentiviral vectors)
- Clinical and commercial GMP manufacturing environments
- Experience supporting regulated markets
xRNA, LNP, pDNA
End-to-end GMP support for xRNA therapies
Novartis provides comprehensive contract manufacturing support for nucleic acid‑based medicines, enabling partners to advance RNA therapies from early clinical supply to commercial production.
Key capabilities
- Manufacturing of RNA products, including siRNA and mRNA
- Master cell bank manufacturing
- Plasmid DNA production
- Peptide synthesis
- Lipid nanoparticle (LNP) formulation
- Drug product manufacturing
Fill & Finish
Flexible, high-quality GMP drug product solutions
Our drug product manufacturing services support a wide range of dosage forms, container systems, and production volumes. We offer both ready‑to‑fill bulk handling and compounding‑based solutions, tailored to program requirements.
Key capabilities
- Aseptic fill & finish
- Liquid and lyophilized products
- Multiple packaging formats:
- Vials
- Pre‑filled syringes
- Cartridges
- Ointments and viscoelastics
- Dropper bottles and sprays
- Tubes
Our global manufacturing sites
Global network with robust supply chain. Located across Europe, the US and Asia, our cGMP-compliant facilities have the people and technology to create high-end solutions efficiently and at scale.
Novartis Global Manufacturing Network
Combine quality and regulatory excellence
Trusted GMP manufacturing supported by rigorous quality systems and deep regulatory experience across global health authorities.
Manufacturing Expertise, Scalability & Flexibility
Expert-led manufacturing with scalable, flexible operations, enabling reliable tech transfer and clinical‑to‑commercial supply across complex modalities.
Responsible & Sustainable Manufacturing
Manufacturing excellence aligned with Novartis’s sustainability commitments, enabling responsible operations and reduced environmental impact across the global network.
Novartis Contract Manufacturing Factsheets
Download our factsheets below to find more information about our services & technologies offering.
