We focus on discovering and advancing new treatments for serious patient needs. From the inception of a therapeutic through early clinical development, our disease area teams collaborate across scientific disciplines and organizations in support of our mission to improve and extend peoples’ lives.

Autoimmunity, Transplantation & Inflammatory Disease

B-cells in a kidney biopsy.


The Autoimmunity, Transplantation & Inflammatory Disease group is developing transformative therapies, including small molecules and biotherapeutics, that target the root cause of disease by modulating the immune system to restore health.

Learn More

Cardiovascular & Metabolic Diseases

Heart muscle cells.


Our Cardiovascular & Metabolic Diseases team works to better understand the root causes of cardiovascular and metabolic diseases, and discover and develop therapies against relevant targets.

Learn More

Exploratory Disease Research (DAx)

Liver cells


DAx catalyzes and drives transformative therapies for emerging, high-potential indications. Current research focuses on liver, respiratory and kidney diseases, as well as non-malignant blood disorders.

Learn More


CAR-T cells in action.


Our Immuno-Oncology researchers are developing a deep and diverse portfolio of potential immune treatments for cancer.

Learn More

Musculoskeletal Diseases

Knee cartilage.


The mission of our Musculoskeletal Diseases research team is to restore mobility and independence to patients living with some of the most intractable of these conditions.

Learn More


Astrocytes in a brain organoid.


Our neuroscience research team works to discover transformative therapies that address the underlying cause of neurodegenerative, neurodevelopmental and psychiatric diseases to dramatically improve the lives of patients.

Learn More


Breast cancer cells.


Our Oncology team is developing a robust portfolio of treatments that destroy tumors selectively and strip away their defenses.

Learn More


Mouse retina


The Ophthalmology research team is working to develop a diverse portfolio of compounds – small molecules, biologics and gene-based treatments – that protect and restore vision.

Learn More

Tropical Diseases

Novartis Institute for tropical diseases


The Novartis Institute for Tropical Diseases is a drug discovery research institute dedicated to finding novel treatments for neglected tropical diseases, including malaria, cryptosporidiosis, and three major kinetoplastid diseases – human African trypanosomiasis, Chagas disease, and leishmaniasis.

Learn More