Active Clinical Trials

Clinical trials are at the heart of our work to bring innovative medicines to people with a particular disease or condition. Learn more about the active studies conducted by Novartis including opportunities to get involved.

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Study title Condition Phase Location NCT ID

A Study to Evaluate the Efficacy of NIO752 in Participants With Progressive Supranuclear Palsy

 		Progressive Supranuclear Palsy Richardson Syndrome (PSP-RS) Phase3 Australia
France
Germany
Italy
Japan
Netherlands
Spain
United States
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 NCT07498426

A Study to Assess the Tolerability of Ianalumab (VAY736) With Investigator's Choice Thrombopoietin Receptor Agonist (IC TPO-RA) in Patients With Primary Immune Thrombocytopenia (ITP)

 		Primary Immune Thrombocytopenia (ITP), Primary Evans Syndrome (ES) Phase2 United States NCT07421167

Long-term Safety and Tolerability of Inclisiran in Participants With HeFH or HoFH Who Have Completed the Pediatric ORION-16, ORION-13, ORION-20, or ORION-19 Studies

 		Heterozygous or Homozygous Familial Hypercholesterolemia Phase3 Taiwan NCT05682378

Study of Pelabresib add-on to Ruxolitinib in Japanese Adult Patients With Myelofibrosis

 		Primary Myelofibrosis (PMF), Post-polycythemia Vera Myelofibrosis (Post-PV MF), Post-essential Thrombocythemia Myelofibrosis (Post-ET MF) Phase1 Japan NCT07340138

Study to Determine the Efficacy and Safety of Asciminib in Pediatric Patients With Ph+ CML-CP

 		Chronic Myelogenous Leukemia, Leukemia, Myelogenous, Chronic, Philadelphia Chromosome Positive Phase2 Australia
Canada
South Korea 		NCT07354074

Long Term Observational Study to Collect in a Real-world populatIon Data on the Treatment Pattern of Secukinumab in Adult Patients With Moderate to Severe HS Within the Italian Population

 		Hidradenitis Suppurativa Italy NCT07543419

REAL-CARE: Real-world Effectiveness of Iptacopan in Italian Patients With Paroxysmal Nocturnal Hemoglobinuria

 		Paroxysmal Nocturnal Hemoglobinuria (PNH) Italy NCT07229235

A Phase 3 Study of Pelabresib (DAK539) and Ruxolitinib in Myelofibrosis (MF)

 		Primary Myelofibrosis (PMF), Post-polycythemia Vera Myelofibrosis (PPV-MF), Post-essential Thrombocythemia Myelofibrosis (PET-MF) Phase3 Argentina
Australia
China
India
South Korea
Switzerland
United States
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 NCT07357727

A Safety and Tolerability Study of HJB647 in Heart Failure Participants With Reduced Ejection Fraction

 		Heart Failure With Reduced Ejection Fraction Phase1 United States NCT07465653

Intravascular Imaging Study of the Effect of Inclisiran on Plaque in Patients With Acute Myocardial Infarction

 		Plaque, Atherosclerotic Phase4 China NCT06372925