REQ-10071756
Feb 16, 2026
Switzerland

Summary

Location: this role can be based in Basel, Switzerland or East Hanover, NJ / Cambridge MA, US. If based in the US, please apply to REQ-10071879.
LI-#hybrid

Novartis is seeking a Global Head, AI Enterprise Transformation to lead the Reimagining Work initiative; a multi‑year effort focused on fundamentally redesigning how work gets done in an AI‑enabled world. It focuses on rethinking work at the activity and decision level, integrating AI and automation where they create value, and evolving operating models, capabilities, and governance so Novartis can achieve sustainable productivity, agility, and better employee experience at scale.

This role will set and drive the strategic direction, execution and enterprise impact of the Reimagining Work initiative over a multi‑year horizon, translating future‑of‑work ambition into tangible, people‑centric and AI‑enabled organizational change at scale.

About the Role

Key responsibilities:

  • Set and continuously refine the enterprise‑wide vision, ambition and roadmap for the Reimagining Work initiative, aligned with business strategy, technological evolution and people and organization priorities.
  • Lead and own the Reimagining Work / Transformation Office end‑to‑end, with full accountability for delivery, outcomes and benefits realization over a multi‑year horizon.
  • Drive disciplined program governance, prioritization and execution, ensuring momentum and translation of strategy into implemented change at scale.
  • Leverage AI, automation, and emerging technologies to redesign work and processes, partnering with technology and digital leaders to enable practical, organization‑ready solutions.
  • Orchestrate enterprise organizational transformation across multiple levers, including organization design, workforce implications, capability shifts, leadership behaviors and culture.
  • Act as a senior enterprise leader and trusted partner to ECN and other senior stakeholders, navigating complexity, trade‑offs and cross‑enterprise dependencies.
  • Lead (directly or indirectly) a high‑performing Transformation Office team, modeling empowering leadership, accountability and a future‑ready culture.

Essential requirements:

  • 10+ years minimum of senior executive experience leading complex, enterprise‑wide transformation programs with demonstrable delivery and impact.
  • Strong consulting mindset combined with deep corporate and business experience; proven ability to design, influence and execute.
  • High level of AI, digital, and technology fluency as it relates to work, process and organizational redesign (versus hands‑on development and engineering).
  • Proven ability to operate with enterprise‑level gravitas, influence senior stakeholders and drive results in highly matrixed environments.
  • Track record of people‑centric leadership, organizational design and large‑scale change management.
  • Bachelor’s degree required, advanced degree (PhD, MD, MBA etc.) highly desirable.

Commitment to Diversity and Inclusion:

Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve.

Accessibility and Accommodation:

Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. 

Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture

Benefits and Rewards: Learn about all the ways we’ll help you thrive personally and professionally.
Read our handbook (PDF 30 MB)

Corporate
General Management
Switzerland
Basel (City)
BD&L & Strategic Planning
Full time
Regular
No
Thriving together - Our story. VIDEO

Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

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REQ-10071756

Global Head, AI Enterprise Transformation

Apply to Job