Novartis Pipeline
Benefiting from our continued focus on innovation, Novartis has one of the industry’s most competitive pipelines. Many of these projects, which include new molecular entities as well as additional indications and different formulations for marketed products, are for medicines that could significantly advance treatment standards for patients worldwide. This table provides an overview of selected projects in development. Please note: the Novartis Pipeline data is updated quarterly.
Download the Novartis Pipeline from the 2024 Annual Report (PDF 0.1 MB)
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AAA603177Lu-NeoBBreast cancerOncology: Solid Tumors Phase 1 Radioligand therapy target GRPR
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AAA603177Lu-NeoBGlioblastoma multiformeOncology: Solid Tumors Phase 1 Radioligand therapy target GRPRLead Indication
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AAA617Pluvicto®Metastatic neuroendocrine prostate cancerOncology: Solid Tumors Phase 1 Radioligand therapy target PSMA
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AAA802225Ac-PSMA-R2Prostate cancerOncology: Solid Tumors Phase 1 Radioligand therapy target PSMALead Indication
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CYX082farabursenAutosomal dominant polycystic kidney diseaseCardiovascular, Renal and Metabolic Phase 1 MIR17 inhibitorLead Indication
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DFT383DFT383CystinosisNeuroscience Phase 1 CTNS gene deliveryLead Indication
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DFV890DFV890Low risk myelodysplastic syndromeOncology: Hematology Phase 1 NLRP3 inhibitor
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DZR123tulmimetostatProstate cancerOncology: Solid Tumors Phase 1 EZH1, EZH2 inhibitor
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ECI830ECI830Breast cancerOncology: Solid Tumors Phase 1 CDK2 inhibitorLead Indication
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EDI048EDI048CryptosporidiosisIn-market Brands and Global Health Phase 1 CpPI(4)K inhibitorLead Indication
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EDK060EDK060Charcot-Marie-Tooth diseaseNeuroscience Phase 1Lead Indication
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ESP359ESP359Solid tumorsOncology: Solid Tumors Phase 1 Radioligand therapy target DLL3Lead Indication
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FXX489177Lu-NNS309Solid tumorsOncology: Solid Tumors Phase 1 Radioligand therapyLead Indication
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HRO761HRO761Solid tumorsOncology: Solid Tumors Phase 1 Werner inhibitorLead Indication
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IPX643IPX643Inflammation-driven diseasesImmunology Phase 1Lead Indication
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ITU512ITU512Sickle cell diseaseIn-market Brands and Global Health Phase 1 HbF inducing agentLead Indication
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KFA115KFA115Solid tumorsOncology: Solid Tumors Phase 1 Novel immunomodulatory agentLead Indication
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MGY825MGY825NSCLCOncology: Solid Tumors Phase 1Lead Indication
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NIO752NIO752Progressive supranuclear palsyNeuroscience Phase 1 Tau antisense oligonucleotideLead Indication
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NIO752NIO752Alzheimer’s diseaseNeuroscience Phase 1 Tau antisense oligonucleotide
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Disclaimer
This information was factually accurate on the date it was published. Novartis assumes no duty to update the information to reflect subsequent developments. Readers should not rely upon the information on this page as current or accurate after its publication date. For the latest information on the Novartis' pipeline, readers should visit the News and Investors sections of our website. This information constitutes forward-looking statements relating to Novartis AG's business, including express or implied discussions regarding potential new products, potential new indications for existing products, or regarding potential future revenues from any such products. Such forward-looking statements reflect the current views of Novartis AG regarding future events, and involve known and unknown risks, uncertainties and other factors that may cause actual results to be materially different from any future results, performance or achievements expressed or implied by such statements. There can be no guarantee that any new products will be approved for sale in any market, or that any new indications will be approved for existing products in any market, or that such products will achieve any particular revenue levels.
In particular, management's expectations could be affected by, among other things, uncertainties involved in the development of new pharmaceutical products; unexpected clinical trial results, including additional analysis of existing clinical data or unexpected new clinical data; unexpected regulatory actions or delays or government regulation generally; the Novartis Group's ability to obtain or maintain patent or other proprietary intellectual property protection, including the uncertainties involved in the US litigation process; competition in general; government, industry, and general public pricing and other political pressures; and other risks and factors referred to in Novartis AG's current Form 20-F on file with the US Securities and Exchange Commission. Should one or more of these risks or uncertainties materialize, or should underlying assumptions prove incorrect, actual results may vary materially from those described herein as anticipated, believed, estimated or expected.