Study Description
The purpose of this observational, prospective, non-interventional, multicenter, open-label, single arm study in Hidradenitis suppurativa (HS) is to assess the treatment pattern of secukinumab in a flexible dosing regimen and decision influencing factors for flexible dosing in a real-world population over 2 years.
The study will collect data from patients during routine secukinumab treatment and will be representative of the real-world patient population eligible for secukinumab treatment in Germany.
In order to attain widespread representation of health care practices related to the use of secukinumab in the approved indication of moderate to severe HS, a broad spectrum of dermatology practices and clinics who are treating patients with HS across Germany will be included.
Interventions
secukinumab
Eligibility Criteria
Inclusion Criteria:
Patients eligible for inclusion in this study have to fulfill all of the following criteria at enrollment:
Patients who provide written informed consent to participate in the study
Male and female patients with ≥18 years of age
Diagnosis of clinically unequivocal moderate to severe HS
Patients for whom a therapy with secukinumab is medically indicated
Documented decision for treatment with marketed secukinumab regardless of this noninterventional study
Treatment with secukinumab according to the latest version of SmPC
Initial treatment with marketed secukinumab planned for up to 1 week before the baseline visit
Exclusion Criteria:
Patients fulfilling any of the following criteria at enrollment are not eligible for inclusion in this study. No additional exclusions may be applied by the investigator, in order to ensure that the study population will be representative of all eligible patients:
Patients who have any contraindications, such as a history of or active inflammatory bowel disease (Crohn´s disease, ulcerative colitis), and are not eligible for treatment with secukinumab according to the SmPC
Any medical or psychological condition in the treating physician's opinion which may prevent the patient from the study participation
Simultaneous participation in any investigational trial or simultaneous participation in another Novartis-sponsored non-interventional study with secukinumab
Previous exposure to IL-17 inhibitors
For biologic-naïve patients, previous exposure to another biologic drug, such as anti-TNF-α inhibitors
Study Location
Novartis Investigative Site
Recruiting
Bremen,28359,Germany
Novartis Investigative Site
Recruiting
Mainz,55128,Germany
Novartis Investigative Site
Recruiting
Koeln,50674,Germany
Novartis Investigative Site
Recruiting
Potsdam,14469,Germany
Novartis Investigative Site
Recruiting
Falkensee,14612,Germany
Novartis Investigative Site
Recruiting
Berlin,13507,Germany
Novartis Investigative Site
Recruiting
Ilmenau,98693,Germany
Novartis Investigative Site
Recruiting
Dresden,01067,Germany
Novartis Investigative Site
Recruiting
Nuernberg,90402,Germany
Novartis Investigative Site
Recruiting
Leipzig,04289,Germany
Novartis Investigative Site
Recruiting
Unna,59423,Germany
Novartis Investigative Site
Recruiting
Aachen,52064,Germany
Novartis Investigative Site
Recruiting
Hamburg,20457,Germany
Novartis Investigative Site
Recruiting
Buxtehude,21614,Germany
Novartis Investigative Site
Recruiting
Marburg,35043,Germany
Novartis Investigative Site
Recruiting
Koeln,51065,Germany
Novartis Investigative Site
Recruiting
Remscheid,42897,Germany
Novartis Investigative Site
Recruiting
Freising,85354,Germany
Novartis Investigative Site
Recruiting
Berlin,13595,Germany
Novartis Investigative Site
Recruiting
Jena,07743,Germany
Novartis Investigative Site
Recruiting
Dresden,01309,Germany
Novartis Investigative Site
Recruiting
Nuernberg,90419,Germany
Novartis Investigative Site
Recruiting
Lingen,49809,Germany
Novartis Investigative Site
Recruiting
Wittlich,54316,Germany
Novartis Investigative Site
Recruiting
Ahaus,48683,Germany
Novartis Investigative Site
Recruiting
Hamburg,22549,Germany
Novartis Investigative Site
Recruiting
Chemnitz,09113,Germany
Novartis Investigative Site
Recruiting
Minden,32429,Germany
Novartis Investigative Site
Recruiting
Krefeld,47798,Germany
Novartis Investigative Site
Recruiting
Geilenkirchen,52511,Germany
Novartis Investigative Site
Recruiting
Rheinstetten Moersch,76287,Germany
Novartis Investigative Site
Recruiting
Bielefeld,33647,Germany
Novartis Investigative Site
Recruiting
Juelich,52428,Germany
Novartis Investigative Site
Recruiting
Duren,52349,Germany
Novartis Investigative Site
Recruiting
Oberasbach,90522,Germany
Novartis Investigative Site
Recruiting
Luebeck,23538,Germany
Novartis Investigative Site
Recruiting
Hannover,30159,Germany
Novartis Investigative Site
Recruiting
Wuppertal,42103,Germany
Novartis Investigative Site
Recruiting
Annaberg-Buchholz,09456,Germany
Novartis Investigative Site
Recruiting
Chemnitz,09117,Germany
Novartis Investigative Site
Recruiting
Moenchengladbach,41063,Germany
Novartis Investigative Site
Recruiting
Kroepelin,18236,Germany
Novartis Investigative Site
Recruiting
Gera,07548,Germany
Novartis Investigative Site
Recruiting
Selters,56242,Germany
Novartis Investigative Site
Recruiting
Karlsruhe,76133,Germany
Novartis Investigative Site
Recruiting
Bochum,44791,Germany
Novartis Investigative Site
Recruiting
Emsdetten,48282,Germany
Novartis Investigative Site
Recruiting
Oelde,59302,Germany
Novartis Investigative Site
Recruiting
Magdeburg,39104,Germany
Novartis Investigative Site
Recruiting
Hasfurt,97437,Germany
Novartis Investigative Site
Recruiting
Bergen,18528,Germany
Novartis Investigative Site
Recruiting
Mönchengladbach,41061,Germany
Novartis Investigative Site
Recruiting
Kulmbach,95326,Germany
Novartis Investigative Site
Recruiting
Delitzsch,04509,Germany
Novartis Investigative Site
Recruiting
Gernsbach,76593,Germany
Novartis Investigative Site
Recruiting
Simmern,55469,Germany
Novartis Investigative Site
Recruiting
Kempen,47906,Germany
Novartis Investigative Site
Recruiting
Brandenburg An Der Havel,14776,Germany
Novartis Investigative Site
Recruiting
Magdeburg,39120,Germany
Novartis Investigative Site
Recruiting
Erlangen,91054,Germany
Novartis Investigative Site
Recruiting
Oelsnitz,09376,Germany
Novartis Investigative Site
Recruiting
Haslach im Kinzigtal,77716,Germany
Novartis Investigative Site
Recruiting
Berlin,12159,Germany
Novartis Investigative Site
Recruiting
Muenchen,81369,Germany
Novartis Investigative Site
Recruiting
Lauf,91207,Germany
Novartis Investigative Site
Recruiting
Dessau Rosslau,06847,Germany
Novartis Investigative Site
Recruiting
Gladbeck,45964,Germany
Novartis Investigative Site
Recruiting
Soest,59494,Germany
Novartis Investigative Site
Recruiting
Kiel,24103,Germany
Novartis Investigative Site
Recruiting
Bremen,28219,Germany
Novartis Investigative Site
Recruiting
Peitz,03185,Germany
Novartis Investigative Site
Recruiting
Mainz,55116,Germany
Novartis Investigative Site
Recruiting
Falkenberg,04895,Germany
Novartis Investigative Site
Recruiting
Berlin,13086,Germany
Novartis Investigative Site
Recruiting
Hofgeismar,34369,Germany
Novartis Investigative Site
Recruiting
Neuwied,56564,Germany
Novartis Investigative Site
Recruiting
Leipzig,04207,Germany
Novartis Investigative Site
Recruiting
Dortmund,44137,Germany
Novartis Investigative Site
Recruiting
Stolberg,52222,Germany
Novartis Investigative Site
Recruiting
Hamburg,20246,Germany
Worldwide Contacts
If the location of your choosing does not feature any contact detail, please reach out using the information below.