REQ-10000461
Apr 17, 2024
USA

Summary

Location: On Site, Cambridge Our Global Genetically Engineered Models (GEMs) Team within Comparative Medicine (CM) supports the expansion of animal science, preclinical care, and research model development furthering research across the world. We are the innovation incubator within in vivo pre-clinical research and are the central partner for in vivo scientific input, organizing and performing all in vivo activities. The Senior Scientist role is a highly technical and/or specialized professional position responsible for supporting several therapeutic and technology driven areas including cardiovascular, renal and metabolic, immunology, neuroscience and oncology, providing high quality & consistent in vivo technical research support within our multi-building, multi-discipline research program. The role is primarily lab-based and on-site

About the Role

Your Key Responsibilities:

  • Microinjection of CRISPR reagents and plasmids as well as embryo transfer and other relevant surgical procedures. Sperm and embryo cryopreservation, IVF, and all supporting activities
  • Other gene transfer techniques, including electroporation. 
  • Contribute to implementation of novel technologies and approaches to genome engineering of animals.
  • Responsible for ensuring compliance with all institutional and regulatory protocols, policies, and guidelines.
  • Regularly complete literature reviews to maintain familiarity with the latest technologies focused on improving current in vivo disease modeling.
  • Conduct presentations of data and results to the Genetically Engineered Models group and project teams.
  • Other duties and responsibilities as may be required.

Role Requirements:

  • Bachelor’s degree in Natural or Life Sciences (Genetics, Development or Molecular Biology preferred)

  • 3+ years of hands-on experience with laboratory techniques necessary for creating new animal models.

  • Preferred experience working in a molecular biology laboratory and/or rodent microinjection laboratory.

  • Detail oriented, knowledgeable around the IACUC/AWC compliance, regulation, able to utilize paper and electronic study protocols, document experiments in laboratory notebook.

  • Advanced computer skills using Excel, OneDrive, Word and Outlook, being able to collect and record research data, having the ability and knowledge to review documentation as a quality control.

  • Must be able to lift 50 lbs. Must be able to work from a standing or sitting position for prolonged time periods and perform repetitive motion tasks

Desireable Requirements:

  • Master’s degree in Biological Sciences with 5+ years of hands-on experience and a significant microinjection record of accomplishment as well as proficiency with relevant animal surgical procedures
  • Basic or advanced understanding of CRISPR technology and experience with CRISPR-mediated animal model generation 
  • Excellent organizational, written, and oral communication skills 

Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining

to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture

Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Commitment to Diversity & Inclusion: The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Novartis Compensation and Benefit Summary: The pay range for this position at commencement of employment is expected to be between $97,600 - $146,400/year; however while salary ranges are effective from 1/1/24 through 12/31/24, fluctuations in the job market may necessitate adjustments to pay ranges during this period.  Further, final pay determinations will depend on various factors, including, but not limited to geographical location, experience level, knowledge, skills, and abilities. The total compensation package for this position may also include other elements, including a sign-on bonus, restricted stock units, and discretionary awards in addition to a full range of medical, financial, and/or other benefits (including 401(k) eligibility and various paid time off benefits, such as vacation, sick time, and parental leave), dependent on the position offered. Details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about

suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network

Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture

Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network

Biomedical Research
Pharma Research
USA
Cambridge (USA)
Research & Development
Full time
Regular
No
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REQ-10000461

Microinjectionist, Senior Scientist– Comparative Medicine

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