393464BR
Mar 04, 2024
USA
About the Role
Internal Job Title: Discovery Postdoctoral Fellow
Location: Onsite, Cambridge, MA
About the role:
Come join Novartis Biomedical Research as a Discovery Fellow and help investigate the underlying mechanisms driving cellular phenotypes associated with chronic inflammation and develop innovative ways to restore cellular homeostasis.
You'll be part of Disease Area Exploratory X (DAx) and Discovery Sciences (DSc) in Cambridge, MA, where you will focus on examining the biology behind disease-driving cell types by leveraging your translational and genetic expertise, and available patient-derived gene signatures. Specifically, you will investigate the mechanisms behind cellular phenotypes associated with chronic inflammation and develop approaches to restore normal cellular states and create translationally-relevant in vitro models.
We are looking for a motivated scientist who can work across the matrix, and is capable of seamlessly navigating both laboratory-based experimentation and data mining responsibilities in a balanced manner (50/50 split). You will be responsible for envisioning a roadmap for scientific execution, bridging the gap between experimental work and data analysis. The outcomes of your work will contribute valuable insights to the broader scientific community and have the potential to advance our cross-organ disease drug discovery endeavors specifically focused on chronic inflammation.
Discovery Fellows have a unique opportunity to conduct innovative, interdisciplinary research and are expected to publish their results in leading journals. We collaborate across scientific and organizational boundaries, with a focus on powerful new technologies that have the potential to help produce therapeutic breakthroughs for patients. You will join our postdoctoral community for dedicated events, including the monthly postdoctoral seminars and our annual Research Day Symposium. All Fellows participate to our robust curriculum designed to develop scientific and professional skills. The postdoctoral term is up to 4 years.
Key responsibilities:
As a Discovery Fellow, you will:
• Design and execute experiments to develop innovative in vitro models of disease-driving cell types, with a focus on macrophages and other immune cells.
• Utilize advanced techniques and omics-informed approaches to construct patient-derived gene signatures and enhance the translational relevance of the models.
• Optimize and validate the models using a (few) targets with a vision to facilitate the publication process and scientific knowledge dissemination.
• Collaborate with a multidisciplinary team of drug hunters to contribute to the understanding of inflammatory processes and support drug discovery efforts.
• Stay updated with the latest advancements and breakthroughs in chronic inflammation research to drive innovation and sharing of knowledge.
• Communicate research findings through presentations, reports, and scientific publications, contributing to the scientific and Novartis community's understanding of chronic inflammatory diseases.
Location: Onsite, Cambridge, MA
About the role:
Come join Novartis Biomedical Research as a Discovery Fellow and help investigate the underlying mechanisms driving cellular phenotypes associated with chronic inflammation and develop innovative ways to restore cellular homeostasis.
You'll be part of Disease Area Exploratory X (DAx) and Discovery Sciences (DSc) in Cambridge, MA, where you will focus on examining the biology behind disease-driving cell types by leveraging your translational and genetic expertise, and available patient-derived gene signatures. Specifically, you will investigate the mechanisms behind cellular phenotypes associated with chronic inflammation and develop approaches to restore normal cellular states and create translationally-relevant in vitro models.
We are looking for a motivated scientist who can work across the matrix, and is capable of seamlessly navigating both laboratory-based experimentation and data mining responsibilities in a balanced manner (50/50 split). You will be responsible for envisioning a roadmap for scientific execution, bridging the gap between experimental work and data analysis. The outcomes of your work will contribute valuable insights to the broader scientific community and have the potential to advance our cross-organ disease drug discovery endeavors specifically focused on chronic inflammation.
Discovery Fellows have a unique opportunity to conduct innovative, interdisciplinary research and are expected to publish their results in leading journals. We collaborate across scientific and organizational boundaries, with a focus on powerful new technologies that have the potential to help produce therapeutic breakthroughs for patients. You will join our postdoctoral community for dedicated events, including the monthly postdoctoral seminars and our annual Research Day Symposium. All Fellows participate to our robust curriculum designed to develop scientific and professional skills. The postdoctoral term is up to 4 years.
Key responsibilities:
As a Discovery Fellow, you will:
• Design and execute experiments to develop innovative in vitro models of disease-driving cell types, with a focus on macrophages and other immune cells.
• Utilize advanced techniques and omics-informed approaches to construct patient-derived gene signatures and enhance the translational relevance of the models.
• Optimize and validate the models using a (few) targets with a vision to facilitate the publication process and scientific knowledge dissemination.
• Collaborate with a multidisciplinary team of drug hunters to contribute to the understanding of inflammatory processes and support drug discovery efforts.
• Stay updated with the latest advancements and breakthroughs in chronic inflammation research to drive innovation and sharing of knowledge.
• Communicate research findings through presentations, reports, and scientific publications, contributing to the scientific and Novartis community's understanding of chronic inflammatory diseases.
Diversity & Inclusion / EEO
We are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.
Accessibility and Reasonable Accommodations: Individuals in need of a reasonable accommodation due to a medical condition or disability for any part of the application process, or to perform the essential functions of a position, please let us know the nature of your request, your contact information and the job requisition number in your message:
Accessibility and Reasonable Accommodations: Individuals in need of a reasonable accommodation due to a medical condition or disability for any part of the application process, or to perform the essential functions of a position, please let us know the nature of your request, your contact information and the job requisition number in your message:
- Novartis: e-mail [email protected] or call +1 (877)395-2339
- Sandoz: e-mail [email protected] or call: +1-609-422-4098
Role Requirements
What You'll Bring to the Role:
• PhD in immunology, cell biology, functional genomics, or a related field (PhD students in the last year of their thesis work, are eligible to apply).
• Background in immune, molecular, or cell biology techniques, such as immune cell culture and manipulation.
• Special consideration is given to candidates who have a proven track record in querying omics datasets and applying them in their research.
• Proven ability to work independently and in a collaborative team environment, fostering productive research collaborations.
• Strong multitasking skills and ability to troubleshoot technical and scientific challenges as they arise.
• Strong publication record or other scientific achievements (i.e. awards, patents, grants).
• Excellent analytical, communication, presentation, and organizational skills.
• Passion for fundamental exploratory research and boundless curiosity.
How to apply:
Please submit your CV and cover letter by April 1 for consideration. Please make sure to discuss in the cover letter how this training program will help you fulfill your career goals. #PDX # LI Onsite
Why Novartis:
Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture
You’ll receive:
You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook: https://www.novartis.com/careers/benefits-rewards
Commitment to Diversity and Inclusion / EEO:
The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.
The pay rate for this position at commencement of employment is expected to be $75,000 per year; however, base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. The total compensation package for this position may also include other elements, including a sign-on bonus, restricted stock units, and discretionary awards in addition to a full range of medical, financial, and/or other benefits (including 401(k) eligibility and various paid time off benefits, such as vacation, sick time, and parental leave), dependent on the position offered. Details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.
Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network
• PhD in immunology, cell biology, functional genomics, or a related field (PhD students in the last year of their thesis work, are eligible to apply).
• Background in immune, molecular, or cell biology techniques, such as immune cell culture and manipulation.
• Special consideration is given to candidates who have a proven track record in querying omics datasets and applying them in their research.
• Proven ability to work independently and in a collaborative team environment, fostering productive research collaborations.
• Strong multitasking skills and ability to troubleshoot technical and scientific challenges as they arise.
• Strong publication record or other scientific achievements (i.e. awards, patents, grants).
• Excellent analytical, communication, presentation, and organizational skills.
• Passion for fundamental exploratory research and boundless curiosity.
How to apply:
Please submit your CV and cover letter by April 1 for consideration. Please make sure to discuss in the cover letter how this training program will help you fulfill your career goals. #PDX # LI Onsite
Why Novartis:
Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture
You’ll receive:
You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook: https://www.novartis.com/careers/benefits-rewards
Commitment to Diversity and Inclusion / EEO:
The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.
The pay rate for this position at commencement of employment is expected to be $75,000 per year; however, base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. The total compensation package for this position may also include other elements, including a sign-on bonus, restricted stock units, and discretionary awards in addition to a full range of medical, financial, and/or other benefits (including 401(k) eligibility and various paid time off benefits, such as vacation, sick time, and parental leave), dependent on the position offered. Details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.
Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network
Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture
Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network
Biomedical Research
DAX - NIBR
USA
Cambridge, MA
NIBRI
Research & Development
Full Time
Regular
No
