Summary
In this role, you will be part of the Critical Reagents team, coordinating the production and inventory management of biological reference standards and critical reagents used in internal and external bioanalytical laboratories. The position requires a strong scientific and laboratory background and project management skills with a focus on critical reagent production, handling, storage, management, and a customer service mindset. You will work with an elite team of scientists involved in the development and qualification of small and large molecule assays supporting pharmacokinetic, pharmacodynamic and immunogenicity studies across all phases of the drug discovery & development pipeline.
About the Role
Major Responsibilities
- Contribute to the design strategies and production platforms to meet the team needs for the outsourced production of critical reagents from both Novartis Biologics database and in-licensing programs.
- Apply scientific expertise, strong organization and documentation skills to the outsourced productions of customized critical reagents, by contributing to the production strategy, identifying and reviewing production protocols, requesting quotes, interacting with vendors, requesting funds, collecting and providing updates to stakeholders on production timelines.
- Identify protocols for cloning, expression, purification and requalification of in-house monoclonal antibodies, recombinant proteins, Stable Isotope Labelled (SIL) proteins in different hosts (Escherichia coli, yeast, insect, mammalian cell cultures and hybridoma cultures).
- Provide scientific expertise and utilize strong collaboration skills to work with colleagues from various departments, stakeholders and external service providers to optimize processes and inventory management systems to meet the needs for outsourced production.
- Provide technical and process troubleshooting and find suitable resolutions.
- Maintain up-to-date documentation, including documentation storage and archiving. Prepare technical documentation as required.
- Provide instruction and technical training to other scientific staff if needed, contributing to team growth
Essential Requirements
- MSc or PhD / Pharm.D. level scientist with appropriate experience in a relevant field.
- 4+ years in the pharmaceutical industry.
- Experience in working in a drug discovery or development or relevant experience in a CRO, Pharma or Biotech highly desirable.
- Experience in working with cross-functional teams in a highly dynamic, matrixed, project-team environment.
- Strong project management, critical thinking, and problem-solving skills.
- Strong oral and written communication skills.
- Ability to work independently with minimal supervision on assigned tasks.
- Experience in planning, launching, and tracking outsourced production of customized reagents.
- Experience in reagent inventory management.
- Experience in SharePoint Site maintenance. Previous hands-on experience creating solutions using KNIME and Spotfire will be an added value.
- Experience in production of monoclonal antibodies, recombinant proteins, Stable Isotope Labelled (SIL) proteins in different hosts (Escherichia coli, yeast, insect, and mammalian cell cultures or hybridoma cultures), including cloning, upstream and downstream processes in biopharmaceutical environment
Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture
Benefits and Rewards: Learn about all the ways we’ll help you thrive personally and professionally.
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Accessibility and accommodation
Novartis is committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to perform the essential functions of a position, please send an e-mail to [email protected] and let us know the nature of your request and your contact information. Please include the job requisition number in your message.
