Обзор
Location: Menges, Slovenia
Role Purpose:
Our R&D unit in Mengeš is looking for a motivated scientist in the field of Mass Spectrometry (MS) to join us and help us develop a diverse portfolio of biotherapeutic modalities.
As a Senior Scientist you must demonstrate a broad and in-depth analytical understanding of MS to evaluate the developability of various biologics modalities covered by Novartis Biomedical Research and Development units, ranging from traditional antibodies to advanced biologics formats and mixed modalities. You will support cell line development, upstream and downstream processing, formulation studies development including analytical material release for in-vivo studies.
We offer a stimulating work environment, ample opportunities for growth and development, and the chance to make a significant impact on the future of medicine. If you are a motivated and talented scientist with a passion for biomedical research, we invite you to apply and become a part of our dynamic team at Novartis.
Naša R&D enota v Mengšu išče motiviranega raziskovalca s področja masne spektrometrije (MS), ki se nam bo pridružil in pomagal razvijati raznolik portfelj bioterapevtikov.
Kot Raziskovalec ekspert morate izkazovati široko in poglobljeno analitično razumevanje MS za ocenjevanje razvojnega potenciala različnih bioloških modalitet, ki jih pokrivajo enote Novartis Biomedicinske raziskave in Razvoj, od tradicionalnih protiteles do naprednih bioloških formatov in mešanih modalitet. Podpirali boste razvoj celičnih linij, procese upstream in downstream, razvoj formulacijskih študij, vključno z analitičnim sproščanjem materiala za in-vivo študije.
Ponujamo spodbudno delovno okolje, številne priložnosti za rast in razvoj ter možnost pomembnega vpliva na prihodnost medicine. Če ste motiviran in nadarjen raziskovalec s strastjo do biomedicinskih raziskav, vas vabimo, da se prijavite in postanete del naše dinamične ekipe v Novartisu
About the Role
Key Responsibilities:
- Analyze and characterize biological candidates by mass spectrometry including sample preparation, analysis, evaluation, interpretation and reporting
- Prepare and communicate analytical strategies and results at internal and external meetings.
- Independently generate hypotheses, design and execute follow-up experiments, and troubleshoot issues
- Author lab procedures and technology evaluations
- Accurately and timely process samples, contribute to result interpretation and prepare summary presentations and timely document all data in electronic lab journal and databases
- Actively undertake organizational responsibilities in lab organization, including maintaining equipment and implementation of new equipment
Minimum Requirements - What you will bring to the role
- MSc degree in biochemistry, biotechnology, chemistry or a related field with at least 3 year of relevant work experience in industry, or BSc University degree in biochemistry, biotechnology, chemistry or a related field with with at least 6 years of relevant work experience in industry.
- Strong scientific background in characterization of recombinant proteins by mass spectrometry including experience with modern LC-MS techniques (Intact/reduced/subunit RPMS, peptide mapping, released glycans). Experience with data analysis workflows and report generation
- Expertise in physical-chemical analysis or other biophysical analysis, such as spectroscopy, calorimetry, light scattering technologies is not mandatory, but considered as a plus
- High learning ability to acquire expertise in new technologies and technical equipment
- Proven experience in successfully prioritizing and keeping timelines
- Open and proactive communication, strong customer focus, ability to interact with various stakeholders
- Reliable and flexible team player, accustomed to sharing tasks and projects
- Fluency in English (oral/written)
Ključne odgovornosti:
- Analiziranje in karakterizacija bioloških kandidatov z masno spektrometrijo, vključno s pripravo vzorcev, analizo, vrednotenjem, interpretacijo in poročanjem
- Priprava in komuniciranje analitičnih strategij ter rezultatov na internih in eksternih sestankih.
- Samostojno oblikovanje hipotez, načrtovanje in izvajanje nadaljnjih eksperimentov ter odpravljanje težav
- Priprava laboratorijskih postopkov in tehnoloških evalvacij
- Natančna in pravočasna obdelava vzorcev, prispevanje k interpretaciji rezultatov, priprava povzetkov predstavitev ter pravočasno dokumentiranje vseh podatkov v elektronskem laboratorijskem dnevniku in podatkovnih bazah
- Aktivno prevzemanje organizacijskih odgovornosti pri organizaciji laboratorija, vključno z vzdrževanjem opreme in uvajanjem nove opreme
Minimalne zahteve – kaj boste prinesli v vlogo
- Univerzitetna izobrazba / magisterij (MSc) iz biokemije, biotehnologije, kemije ali sorodnega področja z najmanj 3 leti ustreznih delovnih izkušenj v industriji; ali Visokošolska izobrazba (BSc) iz biokemije, biotehnologije, kemije ali sorodnega področja z najmanj 6 leti ustreznih delovnih izkušenj v industriji.
- Močno znanstveno ozadje na področju karakterizacije rekombinantnih proteinov z masno spektrometrijo, vključno z izkušnjami s sodobnimi LC-MS tehnikami (intaktna/reducirajoča/podenotna RPMS analiza, peptidno mapiranje, analize glikanov).
- Izkušnje z analizo podatkov in pripravo poročil
- Visoka sposobnost učenja za pridobivanje strokovnega znanja o novih tehnologijah in tehnični opremi
- Dokazane izkušnje z uspešnim določanjem prioritet in spoštovanjem časovnic
- Odprta in proaktivna komunikacija, močna usmerjenost k strankam, sposobnost sodelovanja z različnimi deležniki
- Zanesljiv in prilagodljiv timski igralec, vajen delitve nalog in projektov
- Tekoče znanje angleščine, ustno in pisno
Zaželene sposobnosti
- Strokovno znanje s področja fizikalno-kemijske analize ali drugih biofizikalnih analiz, kot so spektroskopija, kalorimetrija in tehnologije sipanja svetlobe, ni obvezno, vendar predstavlja prednost
Benefits & Rewards
At Novartis, we’re committed to reimagining medicine together - and rewarding the people who make it happen.
Expected Annual Base Salary Range for role: €27,160 to €50,440
The base salary offered is determined based on gender-neutral objectives, such as relevant skills, competencies and experience in accordance with the Novartis pay setting policy and upon joining Novartis will be reviewed periodically.
In addition to your base salary, you may be eligible for a performance-based bonus depending on certain performance parameters.
The rewards of being part of our team go far beyond base pay and incentives. We also offer a variety of competitive benefits in kind to help you thrive personally and professionally, such as insurance plans, retirement plans, wellbeing resources and global recognition programs. In addition, we provide flexible and hybrid working options, where possible, and minimum 14 weeks paid parental leave.
Pričakovani letni osnovni plačni razpon za delovno mesto: €27,160 do € 50,440
Osnovna plača je določena glede na spolno nevtralne cilje, kot so relevantne veščine, kompetence in izkušnje v skladu s politiko plač Novartisa, ob vstopu v Novartis pa se redno pregleduje.
Poleg osnovne plače ste morda upravičeni do bonusa na podlagi uspešnosti, odvisno od določenih parametrov uspešnosti.
Nagrade, ki jih prinaša članstvo v naši ekipi, segajo daleč preko osnovne plače in spodbud. Ponujamo tudi različne konkurenčne ugodnosti v naravi, ki vam pomagajo uspevati osebno in poklicno, kot so zavarovalni načrti, pokojninski načrti, viri za dobro počutje in globalni programi priznanja. Poleg tega ponujamo prilagodljive in hibridne možnosti dela, kjer je mogoče, ter najmanj 14 tednov plačanega starševskega dopusta.
Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture
Benefits and Rewards: Learn about all the ways we’ll help you thrive personally and professionally.
Read our handbook (PDF 30 MB)
Accessibility and accommodation
Novartis is committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to perform the essential functions of a position, please send an e-mail to [email protected] and let us know the nature of your request and your contact information. Please include the job requisition number in your message.
