## [Radioligand Therapy Production in Indianapolis, IN](/us-en/radioligand-therapy-production-indianapolis-indiana "Radioligand Therapy Production in Indianapolis, IN") ![Novartis Radioligand Therapy Production Indianapolis Indiana](/us-en/sites/novartis_us/files/styles/cta_image/public/2025-09/Indianapolis%2C%20Indiana_0.jpg.webp?itok=6zb6KYSz "Novartis Radioligand Therapy Production Indianapolis Indiana") Our 70,000 square-foot radioligand therapy (RLT) manufacturing site in Indianapolis, Indiana, opened in 2024. RLT is a type of precision treatment that pairs a tumor-targeting molecule (ligand) with a therapeutic radioisotope, allowing radiation to be delivered directly to the tumor while minimizing harm to surrounding healthy tissue. The site is being expanded to enable in-house production of isotopes, a critical radioactive component of these therapies. ## Key Facts About the Site 2024 site opened 70K square-foot site 1 of 5 US RLT manufacturing sites ## See Photos from Our Indianapolis Site Learn more about how we’re expanding our site in Indianapolis to include isotope production and see our Wall of Hope, where we place a ribbon to honor each patient who receives a dose of RLT. - ![Novartis radioligand therapy site under construction in Indianapolis](/us-en/sites/novartis_us/files/styles/image_gallery_full_width/public/2025-09/Novartis%20radioligand%20therapy%20site%20under%20construction%20in%20Indianapolis.png.webp?itok=05VJx8o_ "Novartis radioligand therapy site under construction in Indianapolis") View1/4 - ![Man working with doses of radioligand medicine](/us-en/sites/novartis_us/files/styles/image_gallery_full_width/public/2025-09/Man%20working%20with%20doses%20of%20radioligand%20medicine.jpg.webp?itok=WGE9cy_a "Man working with doses of radioligand medicine") View2/4 - ![Wall of Hope](/us-en/sites/novartis_us/files/styles/image_gallery_full_width/public/2026-04/CarouselImage1SamEdit.jpg.webp?itok=ayrxygOn "Wall of Hope") View3/4 - ![Novartis employees talk about the importance of the work they do, and their personal ‘why’ in delivering doses of RLT to patients.](/us-en/sites/novartis_us/files/styles/image_gallery_full_width/public/2026-04/CarouselImage3SamEdit.jpg.webp?itok=eUo72XLi "Novartis employees talk about the importance of the work they do, and their personal ‘why’ in delivering doses of RLT to patients.") View4/4 ![Novartis radioligand therapy site under construction in Indianapolis](/us-en/sites/novartis_us/files/styles/image_gallery_full_width/public/2025-09/Novartis%20radioligand%20therapy%20site%20under%20construction%20in%20Indianapolis.png.webp?itok=05VJx8o_ "Novartis radioligand therapy site under construction in Indianapolis") Expansion is underway at our Indianapolis site to enable in-house production of isotopes. Isotopes are a critical radioactive component of RLT therapies. 1/4 ![Man working with doses of radioligand medicine](/us-en/sites/novartis_us/files/styles/image_gallery_full_width/public/2025-09/Man%20working%20with%20doses%20of%20radioligand%20medicine.jpg.webp?itok=WGE9cy_a "Man working with doses of radioligand medicine") Doses of RLT that are shipped from our five radioligand therapy facilities across the US. Read a story about what it takes to [deliver a dose of RLT to a cancer patient](https://www.novartis.com/us-en/stories/veteran-delivers-cancer-treatment-to-patients). 2/4 ![Wall of Hope](/us-en/sites/novartis_us/files/styles/image_gallery_full_width/public/2026-04/CarouselImage1SamEdit.jpg.webp?itok=ayrxygOn "Wall of Hope") At our RLT manufacturing site in Indiana, we created a Wall of Hope we walk by every day, with ribbons that represent each dose of medicine sent to a patient. 3/4 ![Novartis employees talk about the importance of the work they do, and their personal ‘why’ in delivering doses of RLT to patients.](/us-en/sites/novartis_us/files/styles/image_gallery_full_width/public/2026-04/CarouselImage3SamEdit.jpg.webp?itok=eUo72XLi "Novartis employees talk about the importance of the work they do, and their personal ‘why’ in delivering doses of RLT to patients.") In Indiana, team members post their individual “why”– what makes the work they do to deliver innovative medicines to patients so meaningful. [Learn more about RLT](https://www.novartis.com/us-en/about/radioligand-therapy). 4/4 1. 2. 3. 4. [ Previous](#paragraph--33326) [ Next](#paragraph--33326) ![scientists fist bumping ](/us-en/sites/novartis_us/files/styles/cta_image/public/2026-03/BJORN_NOVARTIS_RLT%20-%20Main%20Sequence%20RePurpose%202%20271025%20AM%20V1.00_00_58_12.Still029.jpg.webp?itok=1X4xkaL8 "Investing in America Hero") ## Explore Career Opportunities in Indianapolis From science roles to manufacturing to business, find the right role at Novartis in the US and join us as we work to reimagine medicine. [Learn More](https://www.novartis.com/careers/career-search?search_api_fulltext=Indianapolis&country%5B0%5D=LOC_US&field_job_posted_date=All&op=Submit&page= "Learn More") ## Featured Stories [ ![Team shot at the groundbreaking, with shovels in sand. ](/us-en/sites/novartis_us/files/styles/cards_1_3/public/2026-04/1.%20Ground%20Breaking%20Shot.jpg.webp?itok=__w3U0mi "Team shot at the groundbreaking, with shovels in sand. ") ### Innovating for America: How Our New RLT Manufacturing Site Can Help Ensure Continued On Time Delivery to Patients Now and in Future As Novartis expands its manufacturing capabilities, our new Carlsbad facility will help deliver time-sensitive cancer treatments to patients, meeting future demand. ](/us-en/stories/innovating-america-new-rlt-manufacturing-site) [ ![2 2001 Aerial photo-d](/us-en/sites/novartis_us/files/styles/cards_1_3/public/2025-08/2%202001%20Aerial%20photo-d.jpg.webp?itok=mfpCqzPc "Aerial view of Novartis Campus Point construction site in San Diego showing multiple research buildings under development with Pacific Ocean visible in background") ### Novartis in San Diego: A Quarter Century of R&D Innovation A look back at a legacy of biomedical research breakthroughs that trace their roots to our San Diego site. ](/us-en/stories/novartis-san-diego-research-development-innovation) [ ![A Novartis employee and Veteran, Matt Baca, featured during his time in the military.](/us-en/sites/novartis_us/files/styles/cards_1_3/public/2025-10/Mattinprofile.png.webp?itok=qayVJj8I "A Novartis employee and Veteran, Matt Baca, featured during his time in the military.") ### How This Former Army Officer Helps Deliver Cancer Treatments to Patients Radioligand therapies harness the power of radioisotopes to target cancer with precision. For Matt Baca, delivering a dose in a three-to-five-day window is all in a day’s work. ](/us-en/stories/veteran-delivers-cancer-treatment-to-patients) ## Latest News [May 07, 2026 - Media Release ### Novartis breaks ground on Denton, Texas radioligand therapy site; construction now underway across all new US facilities ](/us-en/news/media-releases/novartis-breaks-ground-denton-texas-radioligand-therapy-site-construction-now-underway-across-all-new-us-facilities) [Feb 25, 2026 - Media Release ### Novartis to build new radioligand therapy site in Denton, Texas, delivering more next‑generation treatments to patients ](/us-en/news/media-releases/novartis-build-new-radioligand-therapy-site-denton-texas-delivering-more-next-generation-treatments-patients) [Jan 09, 2026 - Media Release ### Novartis to add radioligand therapy manufacturing facility in Winter Park, Florida, fourth in US to serve patients and advance $23 billion investment ](/us-en/news/media-releases/novartis-add-radioligand-therapy-manufacturing-facility-winter-park-florida-fourth-us-serve-patients-and-advance-23-billion-investment) [View More](https://www.novartis.com/us-en/news/news-archive "View More") ## See Our Other US Sites Previous Next [ ![Biomedical Research organization in Cambridge, Massachusetts](/us-en/sites/novartis_us/files/styles/cards_1_3/public/2025-09/Biomedical-Research-organization-in-Cambridge-Massachusetts.png.webp?itok=5KRHlit5 "Biomedical-Research-organization-in-Cambridge-Massachusetts") ### Cambridge, MA This Biomedical Research organization, established in 2003, is dedicated to scientific innovation and drug discovery. ](https://www.novartis.com/us-en/biomedical-research-organization-cambridge-ma) [ ![Novartis Radioligand Therapy Production Carlsbad California](/us-en/sites/novartis_us/files/styles/cards_1_3/public/2025-09/Carlsbad%2C%20California.JPG.webp?itok=GzVy9Yv3 "Novartis Radioligand Therapy Production Carlsbad California") ### Carlsbad, CA Our third US radioligand therapy manufacturing site opened in 2025 and serves patients across the western US, Alaska and Hawaii. ](https://www.novartis.com/us-en/radioligand-therapy-production-carlsbad-ca) [ ![Scientist working in a laboratory with test tubes and scientific equipment](/us-en/sites/novartis_us/files/styles/cards_1_3/public/2026-04/Scientist%20working%20in%20a%20laboratory%20with%20test%20tubes%20and%20scientific%20equipment.jpeg.webp?itok=OKKyXm55 "Scientist working in a laboratory with test tubes and scientific equipment") ### Denton, TX Expected to become fully operational in 2028, our fifth US radioligand manufacturing site will serve patients in the southern US. ](https://www.novartis.com/us-en/radioligand-therapy-production-denton-tx) [ ![Novartis Gene Therapy Production Durham, North Carolina](/us-en/sites/novartis_us/files/styles/cards_1_3/public/2025-12/Durham%2C%20North%20Carolina.jpg.webp?itok=DUwFq60z "Novartis Gene Therapy Production Durham, North Carolina") ### Durham, NC (14TW) Expected to be operational in 2028, the site will house two new facilities for manufacturing biologics and sterile packaging. ](https://www.novartis.com/us-en/14tw-biologics-production-durham-nc) [ ![Novartis Gene Therapy Production Durham North Carolina](/us-en/sites/novartis_us/files/styles/cards_1_3/public/2025-09/Durham%2C%20North%20Carolina.jpg.webp?itok=rm8Uw4Yr "Novartis Gene Therapy Production Durham North Carolina") ### Durham, NC (TriCenter) The site produces innovative gene therapies and is expanding to support sterile filling of biologics into syringes and vials. ](https://www.novartis.com/us-en/tricenter-gene-therapy-production-durham-nc) [ ![Novartis Radioligand Therapy Production Millburn New Jersey](/us-en/sites/novartis_us/files/styles/cards_1_3/public/2025-09/Millburn%2C%20New%20Jersey.JPG.webp?itok=hXJ9CeAC "Novartis Radioligand Therapy Production Millburn New Jersey") ### Millburn, NJ Our first US radioligand therapy manufacturing site opened in 2023. Its on-site production capabilities continue to expand. ](https://www.novartis.com/us-en/radioligand-therapy-production-millburn) [ ![Morrisville, North Carolina](/us-en/sites/novartis_us/files/styles/cards_1_3/public/2026-04/Morrisville%2C%20NC_0.jpg.webp?itok=rCf5foqp "Morrisville, North Carolina") ### Morrisville, NC Two new facilities for production and packaging of small molecule medicines, and active pharmaceutical ingredient manufacturing. ](https://www.novartis.com/us-en/small-molecule-production-morrisville-nc) [ ![Novartis Cell Therapy Production Morris Plains New Jersey ](/us-en/sites/novartis_us/files/styles/cards_1_3/public/2025-09/Morris%20Plains%2C%20New%20Jersey_0.jpg.webp?itok=vYv-K-wX " Novartis Cell Therapy Production Morris Plains New Jersey") ### Morris Plains, NJ Since 2015, the site has specialized in the production of groundbreaking cell therapies. ](https://www.novartis.com/us-en/cell-therapy-production-morris-plains) [ ![Novartis Biomedical Research Center in San Diego, California](/us-en/sites/novartis_us/files/styles/cards_1_3/public/2026-02/Novartis-Biomedical-Research-Center-San-Diego-California.jpg.webp?itok=sGR7oWTC "Novartis Biomedical Research Center in San Diego, California") ### San Diego, CA In 2026, we broke ground on a new global Biomedical Research center designed to accelerate drug discovery. ](https://www.novartis.com/us-en/biomedical-research-center-san-diego-ca?check_logged_in=1) [ ![radioligand therapy manufacturing facility in Winter Park, Florida](/us-en/sites/novartis_us/files/styles/cards_1_3/public/2026-01/Radioligand%20therapy%20manufacturing%20facility%20in%20Winter%20Park%2C%20Florida.jpg.webp?itok=PNmbu9zy "radioligand therapy manufacturing facility in Winter Park, Florida") ### Winter Park, FL Expected to open in 2029, our fourth US radioligand manufacturing site will optimize delivery for patients across the southeastern US. ](https://www.novartis.com/us-en/rlt-therapy-production-winter-park) ### Learn More About Our Investment in the US [Return to Investing in America's Health](https://www.novartis.com/us-en/about/investing-americas-health "Return to Investing in America's Health")