## [Radioligand Therapy Production in Denton, TX ](/us-en/radioligand-therapy-production-denton-texas "Radioligand Therapy Production in Denton, TX ") ![Scientist working in a laboratory with test tubes and scientific equipment](/us-en/sites/novartis_us/files/styles/cta_image/public/2026-04/Scientist%20working%20in%20a%20laboratory%20with%20test%20tubes%20and%20scientific%20equipment.jpeg.webp?itok=kxz1oeHw "Scientist working in a laboratory with test tubes and scientific equipment") Once completed, our new 46,000-square-foot radioligand therapy (RLT) manufacturing site in Denton will be our first manufacturing facility in Texas. The site is expected to become fully operational in 2028. RLT is a type of precision treatment that pairs a tumor-targeting molecule (ligand) with a therapeutic radioisotope, allowing radiation to be delivered directly to the tumor while minimizing harm to surrounding healthy tissue. ## See Photos from Our Denton RLT Manufacturing Site Learn more about the groundbreaking and how the new site expands our coast‑to‑coast RLT network to bring highly personalized cancer therapies closer to patients across the southern United States. - ![Victor Bultó, US President, Novartis, and Steffen Lang, President, Operations, are joined by federal, state and local policymakers](/us-en/sites/novartis_us/files/styles/image_gallery_full_width/public/2026-05/Victor%20Bult%C3%B3%2C%20US%20President%2C%20Novartis%2C%20and%20Steffen%20Lang%2C%20President%2C%20Operations%2C%20joined%20by%20federal%2C%20state%20and%20local%20policy%20makers.png.webp?itok=KuF_dCtb "Victor Bultó, US President, Novartis, and Steffen Lang, President, Operations, are joined by federal, state and local policymakers") View1/5 - ![Steffen Lang, President, Operations at Novartis (right), connects with Global and US RLT leadership before the groundbreaking event in Denton, Texas.](/us-en/sites/novartis_us/files/styles/image_gallery_full_width/public/2026-05/ND-1112.jpg.webp?itok=TSqRVGoL "Steffen Lang, President, Operations at Novartis (right), connects with Global and US RLT leadership before the groundbreaking event in Denton, Texas.") View2/5 - ![Victor Bultó, US President, Novartis, and Steffen Lang, President, Operations, joined by federal, state and local policy makers.](/us-en/sites/novartis_us/files/styles/image_gallery_full_width/public/2026-05/Steffen%20Lang%2C%20President%2C%20Operations%2C%20at%20Novartis%20sits%20down%20with%20Jenesia%20Farral%2C%20Novartis%20RLT%20Production%20Technician%2C%20to%20discuss%20her%20role%20in%20manufacturing%20RLTs%20and%20the%20personal%20impact%20of%20her%20work.png.webp?itok=MjJYUZR4 "Victor Bultó, US President, Novartis, and Steffen Lang, President, Operations, joined by federal, state and local policy makers.") View3/5 - ![The mayor of Denton and City Council members take the stage after the event to celebrate the Denton RLT facility groundbreaking. ](/us-en/sites/novartis_us/files/styles/image_gallery_full_width/public/2026-05/ND-1479.jpg.webp?itok=TBozqrol "The mayor of Denton and City Council members take the stage after the event to celebrate the Denton RLT facility groundbreaking. ") View4/5 - ![Guests celebrate the groundbreaking of our new RLT site in Denton, Texas. ](/us-en/sites/novartis_us/files/styles/image_gallery_full_width/public/2026-05/Guests%20celebrate%20the%20groundbreaking%20of%20our%20new%20RLT%20site%20in%20Denton%2C%20Texas.png.webp?itok=E65FkWap "Guests celebrate the groundbreaking of our new RLT site in Denton, Texas. ") View5/5 ![Victor Bultó, US President, Novartis, and Steffen Lang, President, Operations, are joined by federal, state and local policymakers](/us-en/sites/novartis_us/files/styles/image_gallery_full_width/public/2026-05/Victor%20Bult%C3%B3%2C%20US%20President%2C%20Novartis%2C%20and%20Steffen%20Lang%2C%20President%2C%20Operations%2C%20joined%20by%20federal%2C%20state%20and%20local%20policy%20makers.png.webp?itok=KuF_dCtb "Victor Bultó, US President, Novartis, and Steffen Lang, President, Operations, are joined by federal, state and local policymakers") Victor Bultó, US President, Novartis, and Steffen Lang, President, Operations, are joined by federal, state and local policymakers, as well as other dignitaries and guests, to celebrate the radioligand therapy (RLT) facility groundbreaking in Denton, Texas, on May 7, 2026. 1/5 ![Steffen Lang, President, Operations at Novartis (right), connects with Global and US RLT leadership before the groundbreaking event in Denton, Texas.](/us-en/sites/novartis_us/files/styles/image_gallery_full_width/public/2026-05/ND-1112.jpg.webp?itok=TSqRVGoL "Steffen Lang, President, Operations at Novartis (right), connects with Global and US RLT leadership before the groundbreaking event in Denton, Texas.") Steffen Lang, President, Operations at Novartis (right), connects with Global and US RLT leadership before the groundbreaking event in Denton, Texas. 2/5 ![Victor Bultó, US President, Novartis, and Steffen Lang, President, Operations, joined by federal, state and local policy makers.](/us-en/sites/novartis_us/files/styles/image_gallery_full_width/public/2026-05/Steffen%20Lang%2C%20President%2C%20Operations%2C%20at%20Novartis%20sits%20down%20with%20Jenesia%20Farral%2C%20Novartis%20RLT%20Production%20Technician%2C%20to%20discuss%20her%20role%20in%20manufacturing%20RLTs%20and%20the%20personal%20impact%20of%20her%20work.png.webp?itok=MjJYUZR4 "Victor Bultó, US President, Novartis, and Steffen Lang, President, Operations, joined by federal, state and local policy makers.") Steffen Lang, President, Operations, at Novartis sits down with Jenesia Farral, Novartis RLT Production Technician, to discuss her role in manufacturing RLTs and the personal impact of her work. 3/5 ![The mayor of Denton and City Council members take the stage after the event to celebrate the Denton RLT facility groundbreaking. ](/us-en/sites/novartis_us/files/styles/image_gallery_full_width/public/2026-05/ND-1479.jpg.webp?itok=TBozqrol "The mayor of Denton and City Council members take the stage after the event to celebrate the Denton RLT facility groundbreaking. ") The mayor of Denton and City Council members take the stage after the event to celebrate the Denton RLT facility groundbreaking. 4/5 ![Guests celebrate the groundbreaking of our new RLT site in Denton, Texas. ](/us-en/sites/novartis_us/files/styles/image_gallery_full_width/public/2026-05/Guests%20celebrate%20the%20groundbreaking%20of%20our%20new%20RLT%20site%20in%20Denton%2C%20Texas.png.webp?itok=E65FkWap "Guests celebrate the groundbreaking of our new RLT site in Denton, Texas. ") Guests celebrate the groundbreaking of our new RLT site in Denton, Texas. 5/5 1. 2. 3. 4. 5. [ Previous](#paragraph--35066) [ Next](#paragraph--35066) ## Key Facts About the Site 2028 site expected to open 46K square-foot site 1 of 5 US RLT manufacturing sites ![scientists fist bumping ](/us-en/sites/novartis_us/files/styles/cta_image/public/2026-03/BJORN_NOVARTIS_RLT%20-%20Main%20Sequence%20RePurpose%202%20271025%20AM%20V1.00_00_58_12.Still029.jpg.webp?itok=1X4xkaL8 "Investing in America Hero") ## Explore Career Opportunities in Denton From science roles to manufacturing to business, find the right role at Novartis in the US and join us as we work to reimagine medicine. [Learn More](https://www.novartis.com/careers/career-search?search_api_fulltext=Denton&country%5B%5D=LOC_US&field_job_posted_date=All&op=Submit "Learn More") ## Featured Stories [ ![Novartis Team](/us-en/sites/novartis_us/files/styles/cards_1_3/public/2026-02/Novartis%20team%20at%20an%20event%20on%20stage%20smiling%20together.png.webp?itok=C8nazhye "Novartis Team at an event") ### Innovating for America: How Our New RLT Manufacturing Site Can Help Ensure Continued On Time Delivery to Patients Now and in Future As Novartis expands its manufacturing capabilities, our new Carlsbad facility will help deliver time-sensitive cancer treatments to patients, meeting future demand. ](/us-en/stories/innovating-america-new-rlt-manufacturing-site) [ ![A Novartis employee and Veteran, Matt Baca, featured during his time in the military.](/us-en/sites/novartis_us/files/styles/cards_1_3/public/2025-10/Mattinprofile.png.webp?itok=qayVJj8I "A Novartis employee and Veteran, Matt Baca, featured during his time in the military.") ### How This Former Army Officer Helps Deliver Cancer Treatments to Patients Radioligand therapies harness the power of radioisotopes to target cancer with precision. For Matt Baca, delivering a dose in a three-to-five-day window is all in a day’s work. ](/us-en/stories/veteran-delivers-cancer-treatment-to-patients) [ ![neuron imagen](/us-en/sites/novartis_us/files/styles/cards_1_3/public/2026-02/neuron-image-from-novartis-sciart-collection.png%20%281%29.png.webp?itok=aJ6vlsYB "neuron image from novartis sciart collection") ### What's next in Neuroscience drug discovery A Q&A with Bryan Laffitte, who leads a Novartis team that’s using the tools of genetic medicine to innovate new therapies for neuromuscular and neurodegenerative conditions. ](/us-en/stories/whats-next-neuroscience-drug-discovery-conversation-genetic-medicine-head-bryan-laffitte) ## Latest News [May 07, 2026 - Media Release ### Novartis breaks ground on Denton, Texas radioligand therapy site; construction now underway across all new US facilities ](/us-en/news/media-releases/novartis-breaks-ground-denton-texas-radioligand-therapy-site-construction-now-underway-across-all-new-us-facilities) [Feb 25, 2026 - Media Release ### Novartis to build new radioligand therapy site in Denton, Texas, delivering more next‑generation treatments to patients ](/us-en/news/media-releases/novartis-build-new-radioligand-therapy-site-denton-texas-delivering-more-next-generation-treatments-patients) [Feb 06, 2026 - Media Release ### Novartis breaks ground on new global Biomedical Research center in San Diego to accelerate drug discovery ](/us-en/news/media-releases/novartis-breaks-ground-new-global-biomedical-research-center-san-diego-accelerate-drug-discovery) [View More](https://www.novartis.com/us-en/news/news-archive "View More") ## See Our Other US Sites Previous Next [ ![Biomedical Research organization in Cambridge, Massachusetts](/us-en/sites/novartis_us/files/styles/cards_1_3/public/2025-09/Biomedical-Research-organization-in-Cambridge-Massachusetts.png.webp?itok=5KRHlit5 "Biomedical-Research-organization-in-Cambridge-Massachusetts") ### Cambridge, MA This Biomedical Research organization, established in 2003, is dedicated to scientific innovation and drug discovery. ](https://www.novartis.com/us-en/biomedical-research-organization-cambridge-ma) [ ![Novartis Radioligand Therapy Production Carlsbad California](/us-en/sites/novartis_us/files/styles/cards_1_3/public/2025-09/Carlsbad%2C%20California.JPG.webp?itok=GzVy9Yv3 "Novartis Radioligand Therapy Production Carlsbad California") ### Carlsbad, CA Our third US radioligand therapy manufacturing site opened in 2025 and serves patients across the western US, Alaska and Hawaii. ](https://www.novartis.com/us-en/radioligand-therapy-production-carlsbad-ca) [ ![Novartis Gene Therapy Production, Durham, NC](/us-en/sites/novartis_us/files/styles/cards_1_3/public/2025-12/Novartis%20Gene%20Therapy%20Production%20Durham%2C%20NC.png.webp?itok=-WQCWXPk "Novartis Gene Therapy Production, Durham, NC") ### Durham, NC (14TW) Expected to be operational in 2028, the site will house two new facilities for manufacturing biologics and sterile packaging. ](https://www.novartis.com/us-en/14tw-biologics-production-durham-nc) [ ![Novartis Gene Therapy Production Durham North Carolina](/us-en/sites/novartis_us/files/styles/cards_1_3/public/2025-09/Durham%2C%20North%20Carolina.jpg.webp?itok=rm8Uw4Yr "Novartis Gene Therapy Production Durham North Carolina") ### Durham, NC (TriCenter) The site produces innovative gene therapies and is expanding to support sterile filling of biologics into syringes and vials. ](https://www.novartis.com/us-en/tricenter-gene-therapy-production-durham-nc) [ ![Novartis Radioligand Therapy Production Indianapolis Indiana](/us-en/sites/novartis_us/files/styles/cards_1_3/public/2025-09/Indianapolis%2C%20Indiana_0.jpg.webp?itok=LXoGnbGT "Novartis Radioligand Therapy Production Indianapolis Indiana") ### Indianapolis, IN Our second US radioligand therapy manufacturing site opened in 2024. Expansion of the site is ongoing. ](https://www.novartis.com/us-en/radioligand-therapy-production-indianapolis) [ ![Novartis Radioligand Therapy Production Millburn New Jersey](/us-en/sites/novartis_us/files/styles/cards_1_3/public/2025-09/Millburn%2C%20New%20Jersey.JPG.webp?itok=hXJ9CeAC "Novartis Radioligand Therapy Production Millburn New Jersey") ### Millburn, NJ Our first US radioligand therapy manufacturing site opened in 2023. Its on-site production capabilities continue to expand. ](https://www.novartis.com/us-en/radioligand-therapy-production-millburn) [ ![Morrisville, North Carolina](/us-en/sites/novartis_us/files/styles/cards_1_3/public/2026-04/Morrisville%2C%20NC_0.jpg.webp?itok=rCf5foqp "Morrisville, North Carolina") ### Morrisville, NC Two new facilities for production and packaging of small molecule medicines, and active pharmaceutical ingredient manufacturing. ](https://www.novartis.com/us-en/small-molecule-production-morrisville-nc) [ ![Novartis Cell Therapy Production Morris Plains New Jersey ](/us-en/sites/novartis_us/files/styles/cards_1_3/public/2025-09/Morris%20Plains%2C%20New%20Jersey_0.jpg.webp?itok=vYv-K-wX " Novartis Cell Therapy Production Morris Plains New Jersey") ### Morris Plains, NJ Since 2015, the site has specialized in the production of groundbreaking cell therapies. ](https://www.novartis.com/us-en/cell-therapy-production-morris-plains) [ ![Novartis Biomedical Research Center in San Diego, California](/us-en/sites/novartis_us/files/styles/cards_1_3/public/2026-02/Novartis-Biomedical-Research-Center-San-Diego-California.jpg.webp?itok=sGR7oWTC "Novartis Biomedical Research Center in San Diego, California") ### San Diego, CA In 2026, we broke ground on a new global Biomedical Research center designed to accelerate drug discovery. ](https://www.novartis.com/us-en/biomedical-research-center-san-diego-ca) [ ![radioligand therapy manufacturing facility in Winter Park, Florida](/us-en/sites/novartis_us/files/styles/cards_1_3/public/2026-01/Radioligand%20therapy%20manufacturing%20facility%20in%20Winter%20Park%2C%20Florida.jpg.webp?itok=PNmbu9zy "radioligand therapy manufacturing facility in Winter Park, Florida") ### Winter Park, FL Expected to open in 2029, our fourth US radioligand manufacturing site will optimize delivery for patients across the southeastern US. ](https://www.novartis.com/us-en/rlt-therapy-production-winter-park) ### Learn More About Our Investment in the US [Return to Investing in America’s Health](https://www.novartis.com/us-en/about/investing-americas-health "Return to Investing in America’s Health")