Novartis Global Pipeline

Benefitting from our continued focus on innovation, Novartis has one of the industry’s most competitive pipelines with more than 200 projects in clinical development.

Many of these projects, which include new molecular entities as well as additional indications and different formulations for marketed products, are for medicines that could significantly advance treatment standards for patients worldwide. This table provides an overview of selected projects in development.

For a detailed review of selected projects in confirmatory development, download the complete Novartis Pipeline (PDF 0.1 MB), as of December 31, 2018.

Please note: the Novartis Pipeline data is updated quarterly.

Displaying 21 - 30 of 72 result(s)
New Molecule

ECF843

Dry eye

Ophthalmology

Early Clinical Trials

2022

Boundary lubricant

New Indication

Entresto®

valsartan and sacubitril (as sodium salt complex)

Chronic heart failure with preserved ejection fraction (PEF)

Cardio-Metabolic

Registration Trials – Phase III/Pivotal

2019

Angiotensin receptor/neprilysin inhibitor

New Indication

Entresto®

valsartan and sacubitril (as sodium salt complex)

Post-acute myocardial infarction

Cardio-Metabolic

Registration Trials – Phase III/Pivotal

2020

Angiotensin receptor/neprilysin inhibitor

New Molecule

HDM201

Acute myeloid lymphoma

Oncology

Early Clinical Trials

>=2023

p53-HDM2 inhibitor

New Molecule

INC280

capmatinib

Non-small cell lung cancer (NSCLC)

Oncology

Registration Trials – Phase III/Pivotal

2019

c-MET inhibitor

New Indication

Jakavi®

ruxolitinib

Acute graft-versus-host disease (GVHD)

Oncology

Registration Trials – Phase III/Pivotal

2020

JAK1/JAK2 inhibitor

New Indication

Jakavi®

ruxolitinib

Chronic graft-versus-host disease (GVHD)

Oncology

Registration Trials – Phase III/Pivotal

2020

JAK1/JAK2 inhibitor

New Molecule

KAE609

cipargamin

Malaria

Established Medicines

Early Clinical Trials

>=2023

PfATP4 inhibitor

New Molecule

KAF156

ganaplacide

Malaria

Established Medicines

Early Clinical Trials

>=2023

Imidazolopiperazines derivative

New Indication

Kisqali®

ribociclib

Hormone receptor-positive, HER2-negative breast cancer (HR+, HER2(-) BC) (adjuvant)

Oncology

Registration Trials – Phase III/Pivotal

>=2023

CDK4/6 inhibitor

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Combination abbreviations:
fulv fulvestrant
tmx tamoxifen
gsn goserelin
NSAI Non-steroidal aromatase inhibitor
Taf Tafinlar® (dabrafenib)
Mek Mekinist® (trametinib)
a EU filing, approved in US.
b US filing, approved in EU.
c US filing, submitted in EU.
d US pending submission, approved in EU
e EU filing, submitted in US.

Disclaimer

This information was factually accurate on the date it was published. Novartis assumes no duty to update the information to reflect subsequent developments. Readers should not rely upon the information on this page as current or accurate after its publication date. For the latest information on the Novartis' pipeline, readers should visit the News and Investors sections of our website. This information constitutes forward-looking statements relating to Novartis AG's business, including express or implied discussions regarding potential new products, potential new indications for existing products, or regarding potential future revenues from any such products. Such forward-looking statements reflect the current views of Novartis AG regarding future events, and involve known and unknown risks, uncertainties and other factors that may cause actual results to be materially different from any future results, performance or achievements expressed or implied by such statements. There can be no guarantee that any new products will be approved for sale in any market, or that any new indications will be approved for existing products in any market, or that such products will achieve any particular revenue levels.

In particular, management's expectations could be affected by, among other things, uncertainties involved in the development of new pharmaceutical products; unexpected clinical trial results, including additional analysis of existing clinical data or unexpected new clinical data; unexpected regulatory actions or delays or government regulation generally; the Novartis Group's ability to obtain or maintain patent or other proprietary intellectual property protection, including the uncertainties involved in the US litigation process; competition in general; government, industry, and general public pricing and other political pressures; and other risks and factors referred to in Novartis AG's current Form 20-F on file with the US Securities and Exchange Commission. Should one or more of these risks or uncertainties materialize, or should underlying assumptions prove incorrect, actual results may vary materially from those described herein as anticipated, believed, estimated or expected.