Study Description
The main purpose of this study is to assess preliminary efficacy and safety of CFZ533, LYS006, MAS825 , LOU064 and VAY736 in patients with moderate to severe hidradenitis suppurativa and to determine if CFZ533, LYS006, MAS825, LOU064 and VAY736 have an adequate clinical profile for further clinical development.
Interventions
CFZ533
LOU064 100mg
LOU064 25mg
LYS006
MAS825
Placebo to CFZ533
Placebo to LOU064
Placebo to LYS006
Placebo to MAS825
Placebo to VAY736
VAY736
Eligibility Criteria
Inclusion Criteria:
Patients with moderate to severe HS based on the number of lesions, fistulae and anatomical areas involved
Minimal body weight of 50 kg
Able to communicate well with the investigator and understand and comply with the requirements of the study, and the ability and willingness to conduct study visits as per the study schedule
Exclusion Criteria:
Use of other investigational drugs at the time of screening or before
Women physiologically capable of becoming pregnant, unless they are using highly effective methods of contraception
Pregnant or lactating women
Other protocol-defined inclusion/exclusion criteria may apply
Study Location
Novartis Investigative Site
Recruiting
Graz,8036,Austria
Novartis Investigative Site
Recruiting
Bruxelles,1070,Belgium
Novartis Investigative Site
Recruiting
Marseille Cedex 05,13885,France
Novartis Investigative Site
Recruiting
Nice,06202,France
Novartis Investigative Site
Recruiting
Reims,51100,France
Novartis Investigative Site
Recruiting
Rouen Cedex,76031,France
Novartis Investigative Site
Recruiting
Antony,92160,France
Novartis Investigative Site
Recruiting
Lyon,69437,France
Novartis Investigative Site
Recruiting
Frankfurt,60590,Germany
Novartis Investigative Site
Recruiting
Bochum,44791,Germany
Novartis Investigative Site
Recruiting
Hamburg,20246,Germany
Novartis Investigative Site
Recruiting
Debrecen,4032,Hungary
Novartis Investigative Site
Recruiting
Sabadell,Barcelona,08208,Spain
Novartis Investigative Site
Recruiting
Barcelona,08041,Spain
Novartis Investigative Site
Recruiting
Madrid,28031,Spain
Novartis Investigative Site
Recruiting
Granada,18012,Spain
Novartis Investigative Site
Recruiting
Manises,Valencia,46940,Spain
Novartis Investigative Site
Recruiting
Valencia,Comunidad Valenciana,46026,Spain
Novartis Investigative Site
Recruiting
Las Palmas de Gran Canaria,35010,Spain
Novartis Investigative Site
Recruiting
Tampa,Florida,33609,United States
Novartis Investigative Site
Recruiting
Tampa,Florida,33612,United States
Novartis Investigative Site
Recruiting
Charleston,South Carolina,29425,United States
Novartis Investigative Site
Recruiting
Indianapolis,Indiana,46256,United States
Novartis Investigative Site
Recruiting
Evanston,Illinois,60201,United States
Worldwide Contacts
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