Brief Title: Study of Efficacy and Safety of Canakinumab as Adjuvant Therapy in Adult Subjects With Stages AJCC/UICC v. 8 II-IIIA and IIIB (T>5cm N2) Completely Resected Non-small Cell Lung Cancer Acronym: CANOPY-A

A Phase III, Multicenter, Randomized, Double Blind, Placebo-controlled Study Evaluating the Efficacy and Safety of Canakinumab Versus Placebo as Adjuvant Therapy in Adult Subjects With Stages AJCC/UICC v. 8 II -IIIA and IIIB (T>5cm N2) Completely Resected (R0) Non-small Cell Lung Cancer (NSCLC)

ClinicalTrials.gov Identifier: NCT03447769

Novartis Reference Number: CACZ885T2301

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All compounds are either investigational or being studied for (a) new use(s). Efficacy and safety have not been established. There is no guarantee that they will become commercially available for the use(s) under investigation. 

Study Description

The primary purpose of the study is to compare the efficacy and safety of canakinumab versus placebo as adjuvant therapy in adult subjects with stages AJCC/UICC v. 8 II -IIIA and the subset of IIIB (T>5cm N2 disease) completely resected (R0) non-small cell lung cancer (NSCLC).

Condition 
Non-Small Cell Lung Cancer
Phase 
Phase 3
Overall status 
Recruiting
Enrollment count 
1500 participants
Start date 
Mar 16, 2018
Completion date 
Jan 15, 2027
Gender 
All
Age(s)
18 Years and older (Adult, Older Adult)

Interventions

Drug
Canakinumab
Canakinumab will be administered periodically for approximately 54 weeks.
Drug
Placebo
Placebo will be administered periodically for approximately 54 weeks.

Eligibility Criteria

Inclusion Criteria:

Have completely resected (R0) NSCLC AJCC/UICC v. 8 stage IIA-IIIA and IIIB (N2 disease only) OR have NSCLC Stage IIA-IIIA, IIIB (N2 disease only) and are candidates for complete resection surgery
Must have recovered from all toxicities related to prior systemic therapy to grade ≤ 1 (CTCAE v 4.03). Exception to this criterion: subjects with any grade of alopecia and grade 2 or less neuropathy are allowed to enter the study
Have ECOG performance status (PS) of 0 or 1

Exclusion Criteria:

Have unresectable or metastatic disease, positive microscopic margins on the pathology report, and/or gross disease remaining at the time of surgery
Have received neoadjuvant chemotherapy or neoadjuvant radiotherapy
Presence or history of a malignant disease, other than the resected NSCLC, that has been diagnosed and/or required therapy within the past 3 years Exceptions to this exclusion include the following: completely resected basal cell and squamous cell skin cancers, completely resected carcinoma in situ of any type and hormonal maintenance for breast and prostate cancer > 3 years.
Have a history of current diagnosis of cardiac disease
Have uncontrolled diabetes
Have known active or recurrent hepatic disorder including cirrhosis, hepatitis B and C (positive or indeterminate central laboratory results)
Subjects must be evaluated for tuberculosis as per local treatment guidelines or clinical practice. Subjects with active tuberculosis are not eligible.
Have suspected or proven immunocompromised state as described in the protocol
Had Live and attenuated vaccination within 3 months prior to first dose of study drug (e.g. MMR, Yellow Fever, Rotavirus, Smallpox, etc.).

Study Locations

United States
Arizona Oncology Associates PC HAL
Withdrawn
Sedona, 86336
Arizona
United States
Highlands Oncology Group
Recruiting
Fayetteville, 72703
Arkansas
United States
Comprehensive Blood and Cancer Center
Recruiting
Bakersfield, 93309
California
United States
Beverly Hills Cancer Center
Recruiting
Beverly Hills, 90211
California
United States
St. Jude Heritage Medical Group Virginia Crosson Cancer Center
Recruiting
Fullerton, 92835
California
United States
Cancer and Blood Specialty Clinic
Recruiting
Los Alamitos, 90720
California
United States
Los Angeles Hematology/Oncology Medical Group LA Cancer Network
Recruiting
Los Angeles, 90017
California
United States
University of California at Los Angeles
Recruiting
Los Angeles, 90095
California
United States
VA Palo Alto Health Care System CRLX030A2301
Recruiting
Palo Alto, 94304-1207
California
United States
Mercy Dignity Health of Greater Sacramento
Recruiting
Sacramento, 95816
California
United States
Sansum Clinic
Recruiting
Santa Barbara, 93105
California
United States
Central Coast Medical Oncology Corporation Onc Dept
Withdrawn
Santa Maria, 93454
California
United States
Rocky Mountain Regional VAMC
Recruiting
Aurora, 80045
Colorado
United States
Rocky Mountain Cancer Centers Denver-Mdtn(Bone&MarrowTransp)
Recruiting
Greenwood Village, 80220
Colorado
United States
Florida Cancer Specialists
Recruiting
Fort Myers, 33901
Florida
United States
Advanced Medical Specialties Drug Ship - 2
Recruiting
Miami, 33176
Florida
United States
Florida Cancer Affiliates of Ocala
Recruiting
Ocala, 34471
Florida
United States
Florida Cancer Specialists North
Recruiting
Saint Petersburg, 33705
Florida
United States
Florida Cancer Specialists Panhandle
Recruiting
Tallahassee, 32308
Florida
United States
Florida Cancer Specialists
Recruiting
West Palm Beach, 33401
Florida
United States
Atlanta VA Medical Center CSPP100A2366
Recruiting
Decatur, 30033
Georgia
United States
Rush University Medical Center CLDT600AUS06
Recruiting
Chicago, 60612
Illinois
United States
Fort Wayne Medical Oncology/Hematology, Inc. Jefferson Blvd
Recruiting
Fort Wayne, 46815
Indiana
United States
Cancer Center of Kansas Dept.ofCancerCtr.ofKansas
Recruiting
Wichita, 67214-3728
Kansas
United States
Maryland Oncology Hematology P A
Recruiting
Silver Spring, 20904
Maryland
United States
VA Ann Arbor Health System VA Ann Arbor Health System
Recruiting
Ann Arbor, 48105
Michigan
United States
Kansas City VA Medical Center KCVA Med Ctr
Recruiting
Kansas City, 64128
Missouri
United States
HCA Midwest Division
Recruiting
Kansas City, 64132
Missouri
United States
Mercy Medical Research Institute SC-1
Recruiting
Manchester, 63021
Missouri
United States
Johan Cochrane VA
Recruiting
Saint Louis, 63106
Missouri
United States
VA Nebraska-Western Iowa Health Care System
Recruiting
Omaha, 68105
Nebraska
United States
Nebraska Cancer Specialists Regulatory Dept
Withdrawn
Omaha, 68154
Nebraska
United States
New York Oncology Hematology NYOH at Albany Medical Center
Withdrawn
Albany, 12208
New York
United States
Durham VA Medical Center Durham VA Med Ctr -Station 558
Recruiting
Durham, 27705
North Carolina
United States
W G Bill Hefner VA Medical Center
Recruiting
Salisbury, 28144
North Carolina
United States
Louis Stokes Cleveland Department of Veterans Affairs MC
Recruiting
Cleveland, 44106
Ohio
United States
Oncology Associates of Oregon, PC
Recruiting
Eugene, 97401-8122
Oregon
United States
Pittsburgh VA Medical Center
Recruiting
Pittsburgh, 15240
Pennsylvania
United States
Chattanooga Oncology and Hematology Assoicates, PC Chattanooga Oncology
Recruiting
Chattanooga, 37404
Tennessee
United States
Sarah Cannon Research Institute
Recruiting
Nashville, 37203
Tennessee
United States
Texas Cancer Center - Abilene
Recruiting
Abilene, 79606
Texas
United States
Texas Oncology, PA - Bedford
Withdrawn
Bedford, 76022
Texas
United States
VA North Texas Health Care System
Recruiting
Dallas, 75216
Texas
United States
Texas Oncology MamieMcFaddenWardCtr
Recruiting
Dallas, 75246
Texas
United States
Texas Oncology P A SC-3
Withdrawn
Dallas, 75251
Texas
United States
Texas Oncology P A
Withdrawn
Dallas, 75251
Texas
United States
Texas Oncology, P.A. Texas Oncology PA (3)
Withdrawn
Fort Worth, 76104
Texas
United States
Cancer Care Centers of South Texas HOAST CCC of So. TX- San Antonio
Recruiting
San Antonio, 78229
Texas
United States
US Oncology P A
Withdrawn
Tyler, 75702
Texas
United States
Texas Oncology, P.A. - Deke Slayton Cancer Center
Withdrawn
Webster, 77598-4420
Texas
United States
Virginia Cancer Specialists Fairfax Northern Virginia
Recruiting
Fairfax, 22031
Virginia
United States
Oncology and Hematology Associates of Southwest Virginia Inc
Recruiting
Salem, 24153
Virginia
United States
Argentina
Novartis Investigative Site
Withdrawn
Berazategui, B1884BBF
Buenos Aires
Argentina
Novartis Investigative Site
Recruiting
Caba, C1118AAT
Buenos Aires
Argentina
Novartis Investigative Site
Recruiting
Caba, C1426ANZ
Buenos Aires
Argentina
Novartis Investigative Site
Recruiting
Mar del Plata, B7600FZN
Buenos Aires
Argentina
Novartis Investigative Site
Recruiting
Rosario, S2000DSV
Santa Fe
Argentina
Novartis Investigative Site
Recruiting
Rosario, S200KZE
Sante Fe
Argentina
Novartis Investigative Site
Recruiting
Rio Negro, 8500
Viedma
Argentina
Novartis Investigative Site
Recruiting
Cordoba, X5016KEH
-
Argentina
Austria
Novartis Investigative Site
Recruiting
Graz, 8036
-
Austria
Novartis Investigative Site
Recruiting
Klagenfurt, 9020
-
Austria
Novartis Investigative Site
Recruiting
Krems, A-3500
-
Austria
Novartis Investigative Site
Recruiting
Vienna, A-1090
-
Austria
Brazil
Novartis Investigative Site
Recruiting
Teresina, 64049-200
Piaui
Brazil
Novartis Investigative Site
Active, not recruiting
Londrina, 86015-520
PR
Brazil
Novartis Investigative Site
Withdrawn
Rio De Janiero, 20231-050
RJ
Brazil
Novartis Investigative Site
Recruiting
Porto Alegre, 90880-480
RS
Brazil
Novartis Investigative Site
Withdrawn
Itajai, 88301-229
SC
Brazil
Novartis Investigative Site
Active, not recruiting
Barretos, 14784 400
SP
Brazil
Novartis Investigative Site
Active, not recruiting
Sao Paulo, 03102-002
SP
Brazil
Bulgaria
Novartis Investigative Site
Active, not recruiting
Sofia, 1303
-
Bulgaria
Novartis Investigative Site
Recruiting
Sofia, 1407
-
Bulgaria
Novartis Investigative Site
Active, not recruiting
Sofia, 1756
-
Bulgaria
Novartis Investigative Site
Recruiting
Sofia, 1784
-
Bulgaria
Canada
Novartis Investigative Site
Recruiting
Edmonton, T6G 1Z2
Alberta
Canada
Novartis Investigative Site
Recruiting
Moncton, E1C 6Z8
New Brunswick
Canada
Novartis Investigative Site
Recruiting
Hamilton, L8V 5C2
Ontario
Canada
Novartis Investigative Site
Recruiting
Montreal, H2W 1T8
Quebec
Canada
Novartis Investigative Site
Recruiting
Quebec, GIV 4G5
-
Canada
Chile
Novartis Investigative Site
Recruiting
Temuco, 4810469
Araucania
Chile
Novartis Investigative Site
Recruiting
Santiago, 7500921
-
Chile
Novartis Investigative Site
Active, not recruiting
Santiago,
-
Chile
China
Novartis Investigative Site
Recruiting
Hefei, 230001
Anhui
China
Novartis Investigative Site
Recruiting
Beijing, 100039
Beijing
China
Novartis Investigative Site
Recruiting
Beijing,
Beijing
China
Novartis Investigative Site
Recruiting
Chongqing, 400037
Chongqing
China
Novartis Investigative Site
Recruiting
Guangzhou, 510000
Guangdong
China
Novartis Investigative Site
Recruiting
Zhanjing, 524000
Guangong
China
Novartis Investigative Site
Recruiting
Harbin, 150081
Heilongjiang
China
Novartis Investigative Site
Recruiting
Zhengzhou, 450008
Henan
China
Novartis Investigative Site
Recruiting
Wuhan, 430022
Hubei
China
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Recruiting
Nanjing, 210008
Jiangsu
China
Novartis Investigative Site
Recruiting
Suzhou, 215004
Jiangsu
China
Novartis Investigative Site
Recruiting
Chang Chun, 130021
Jilin
China
Novartis Investigative Site
Recruiting
Shenyang, 110011
Liaoning
China
Novartis Investigative Site
Recruiting
Shanghai, 200032
Shanghai
China
Novartis Investigative Site
Recruiting
Shanghai, 200433
Shanghai
China
Novartis Investigative Site
Recruiting
XI An, 710061
Shanxi
China
Novartis Investigative Site
Recruiting
Shenyang, 110041
Shengyang
China
Novartis Investigative Site
Recruiting
Chengdu, 610041
Sichuan
China
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Recruiting
Hangzhou, 310003
Zhejiang
China
Novartis Investigative Site
Recruiting
Hangzhou, 310022
Zhejiang
China
Novartis Investigative Site
Recruiting
Beijing, 100021
-
China
Novartis Investigative Site
Active, not recruiting
Beijing, 100036
-
China
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Recruiting
Changsha, 410013
-
China
Novartis Investigative Site
Recruiting
Chengdu,
-
China
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Recruiting
Fujian, 350001
-
China
Novartis Investigative Site
Active, not recruiting
Tianjin, 300000
-
China
Novartis Investigative Site
Recruiting
Tianjin, 300052
-
China
Colombia
Novartis Investigative Site
Recruiting
Bogota, 110231
-
Colombia
Novartis Investigative Site
Recruiting
Bogotá,
-
Colombia
Novartis Investigative Site
Withdrawn
Monteria,
-
Colombia
Czechia
Novartis Investigative Site
Recruiting
Ostrava Vitkovice, 703 84
-
Czechia
Novartis Investigative Site
Active, not recruiting
Prague 2, 128 21
-
Czechia
Novartis Investigative Site
Recruiting
Prague 5, 150 00
-
Czechia
France
Novartis Investigative Site
Recruiting
Marseille cedex 20, 13915
Bouches Du Rhone
France
Novartis Investigative Site
Recruiting
Le Mans, 72037
Cedex 09
France
Novartis Investigative Site
Withdrawn
Limoges cedex, 87000
Haute Vienne
France
Novartis Investigative Site
Recruiting
Montpellier cedex 5, 34059
Herault
France
Novartis Investigative Site
Recruiting
Amiens Cedex 1, 80054
-
France
Novartis Investigative Site
Recruiting
Angers Cedex 9, 49933
-
France
Novartis Investigative Site
Recruiting
Avignon Cedex, 84902
-
France
Novartis Investigative Site
Recruiting
Bayonne, 64109
-
France
Novartis Investigative Site
Recruiting
Brest, 29200
-
France
Novartis Investigative Site
Recruiting
Bron, 69677
-
France
Novartis Investigative Site
Recruiting
Clermont-Ferrand, 63000
-
France
Novartis Investigative Site
Recruiting
Creteil, 94000
-
France
Novartis Investigative Site
Recruiting
La Rochelle, 17019
-
France
Novartis Investigative Site
Recruiting
LILLE Cédex, 59037
-
France
Novartis Investigative Site
Recruiting
Mulhouse cedex, 68070
-
France
Novartis Investigative Site
Recruiting
Paris, 75231
-
France
Novartis Investigative Site
Recruiting
Paris, 75679
-
France
Novartis Investigative Site
Recruiting
Pau, 64000
-
France
Novartis Investigative Site
Recruiting
Pessac, 33604
-
France
Novartis Investigative Site
Recruiting
Poitiers, 86000
-
France
Novartis Investigative Site
Recruiting
Saint Mande, 94163
-
France
Novartis Investigative Site
Recruiting
Saint-Herblain Cédex, 44805
-
France
Novartis Investigative Site
Recruiting
Strasbourg Cedex, 67091
-
France
Novartis Investigative Site
Recruiting
Suresnes, 92150
-
France
Novartis Investigative Site
Recruiting
Toulouse Cedex 9, 31059
-
France
Novartis Investigative Site
Recruiting
Vandoeuvre-les-Nancy cedex, 54519
-
France
Germany
Novartis Investigative Site
Recruiting
Heidelberg, 69126
Baden-Württemberg
Germany
Novartis Investigative Site
Recruiting
Gauting, 82131
Bayern
Germany
Novartis Investigative Site
Recruiting
Bochum, 44791
Nordrhein Westfalen
Germany
Novartis Investigative Site
Recruiting
Aachen, 52074
-
Germany
Novartis Investigative Site
Recruiting
Berlin, 12351
-
Germany
Novartis Investigative Site
Recruiting
Berlin, 13125
-
Germany
Novartis Investigative Site
Recruiting
Berlin, 14165
-
Germany
Novartis Investigative Site
Recruiting
Chemnitz, 09113
-
Germany
Novartis Investigative Site
Recruiting
Dresden, 01307
-
Germany
Novartis Investigative Site
Recruiting
Erfurt, 99089
-
Germany
Novartis Investigative Site
Recruiting
Essen, 45147
-
Germany
Novartis Investigative Site
Recruiting
Georgsmarienhuette, 49124
-
Germany
Novartis Investigative Site
Recruiting
Gera, 07548
-
Germany
Novartis Investigative Site
Recruiting
Gerlingen, 70839
-
Germany
Novartis Investigative Site
Recruiting
Grosshansdorf, 22947
-
Germany
Novartis Investigative Site
Recruiting
Halle (Saale), 06120
-
Germany
Novartis Investigative Site
Recruiting
Hamm, D 59063
-
Germany
Novartis Investigative Site
Recruiting
Koeln, 51109
-
Germany
Novartis Investigative Site
Recruiting
Leipzig, 04357
-
Germany
Novartis Investigative Site
Recruiting
Loewenstein, 74245
-
Germany
Novartis Investigative Site
Recruiting
Minden, 32429
-
Germany
Novartis Investigative Site
Recruiting
Muenchen, 81377
-
Germany
Novartis Investigative Site
Recruiting
Nuernberg, 90419
-
Germany
Novartis Investigative Site
Recruiting
Solingen, 42699
-
Germany
Novartis Investigative Site
Recruiting
Ulm, 89081
-
Germany
Novartis Investigative Site
Recruiting
Wuerzburg, 97074
-
Germany
Greece
Novartis Investigative Site
Recruiting
Athens, 15562
Attica
Greece
Novartis Investigative Site
Recruiting
Athens, 115 27
GR
Greece
Novartis Investigative Site
Recruiting
Athens, 11526
-
Greece
Novartis Investigative Site
Active, not recruiting
Athens, GR14564
-
Greece
Novartis Investigative Site
Recruiting
Thessaloniki, 57001
-
Greece
Guatemala
Novartis Investigative Site
Recruiting
Guatemala City, 01010
GTM
Guatemala
Novartis Investigative Site
Recruiting
Guatemala City, 01010
-
Guatemala
Novartis Investigative Site
Recruiting
Guatemala, 01010
-
Guatemala
Hong Kong
Novartis Investigative Site
Recruiting
Hong Kong,
-
Hong Kong
Novartis Investigative Site
Recruiting
Kowloon,
-
Hong Kong
Novartis Investigative Site
Recruiting
Tuen Mun,
-
Hong Kong
Hungary
Novartis Investigative Site
Active, not recruiting
Torokbalint, 2045
Pest
Hungary
Novartis Investigative Site
Recruiting
Budapest, 1121
-
Hungary
Novartis Investigative Site
Active, not recruiting
Veszprem, 8200
-
Hungary
Iceland
Novartis Investigative Site
Recruiting
Reykjavik, IS-101
-
Iceland
India
Novartis Investigative Site
Withdrawn
Bangalore, 560 095
Karnataka
India
Novartis Investigative Site
Recruiting
Mumbai, 400022
Maharashtra
India
Novartis Investigative Site
Active, not recruiting
Nashik, 422 004
Maharashtra
India
Novartis Investigative Site
Recruiting
Kolkata, 700160
West Bengal
India
Novartis Investigative Site
Recruiting
Delhi, 110 085
-
India
Novartis Investigative Site
Recruiting
Mumbai, 400 012
-
India
Israel
Novartis Investigative Site
Withdrawn
Beer-Sheva, 8457108
-
Israel
Novartis Investigative Site
Active, not recruiting
Haifa, 3525408
-
Israel
Novartis Investigative Site
Recruiting
Holon, 58100
-
Israel
Novartis Investigative Site
Withdrawn
Jerusalem, 91031
-
Israel
Novartis Investigative Site
Recruiting
Petach Tikva, 49100
-
Israel
Novartis Investigative Site
Recruiting
Rehouot-Zrifin,
-
Israel
Italy
Novartis Investigative Site
Recruiting
Ancona, 60126
AN
Italy
Novartis Investigative Site
Recruiting
Bari, 70124
BA
Italy
Novartis Investigative Site
Recruiting
Bologna, 40138
BO
Italy
Novartis Investigative Site
Recruiting
Meldola, 47014
FC
Italy
Novartis Investigative Site
Recruiting
Monza, 20900
MB
Italy
Novartis Investigative Site
Recruiting
Milano, 20132
MI
Italy
Novartis Investigative Site
Recruiting
Milano, 20133
MI
Italy
Novartis Investigative Site
Recruiting
Padova, 35100
PD
Italy
Novartis Investigative Site
Recruiting
Pisa, 56124
PI
Italy
Novartis Investigative Site
Recruiting
Aviano, 33081
PN
Italy
Novartis Investigative Site
Recruiting
Ravenna, 48100
RA
Italy
Novartis Investigative Site
Recruiting
Reggio Emilia, 42123
RE
Italy
Novartis Investigative Site
Recruiting
Roma, 00189
RM
Italy
Novartis Investigative Site
Recruiting
Orbassano, 10043
TO
Italy
Novartis Investigative Site
Recruiting
Napoli, 80131
-
Italy
Novartis Investigative Site
Recruiting
Perugia, 06129
-
Italy
Japan
Novartis Investigative Site
Recruiting
Nagoya, 464 8681
Aichi
Japan
Novartis Investigative Site
Recruiting
Nagoya, 466 8560
Aichi
Japan
Novartis Investigative Site
Recruiting
Hirosaki, 036 8563
Aomori
Japan
Novartis Investigative Site
Recruiting
Matsuyama, 791-0280
Ehime
Japan
Novartis Investigative Site
Recruiting
Iizuka-city, 820-8505
Fukuoka
Japan
Novartis Investigative Site
Recruiting
Asahikawa-city, 070-8644
Hokkaido
Japan
Novartis Investigative Site
Recruiting
Sapporo city, 060 8648
Hokkaido
Japan
Novartis Investigative Site
Recruiting
Himeji, 670-8520
Hyogo
Japan
Novartis Investigative Site
Recruiting
Kanazawa-city, 920-8641
Ishikawa
Japan
Novartis Investigative Site
Recruiting
Shiwa-gun, 028-3695
Iwate
Japan
Novartis Investigative Site
Recruiting
Yokohama-city, 236 0051
Kanagawa
Japan
Novartis Investigative Site
Recruiting
Yokohama-city, 241-8515
Kanagawa
Japan
Novartis Investigative Site
Recruiting
Natori, 981-1293
Miyagi
Japan
Novartis Investigative Site
Recruiting
Hirakata-city, 573-1191
Osaka
Japan
Novartis Investigative Site
Recruiting
Osaka-city, 541-8567
Osaka
Japan
Novartis Investigative Site
Recruiting
Sakai, 591-8555
Osaka
Japan
Novartis Investigative Site
Recruiting
Hidaka-city, 350-1298
Saitama
Japan
Novartis Investigative Site
Recruiting
Sunto Gun, 411 8777
Shizuoka
Japan
Novartis Investigative Site
Recruiting
Bunkyo ku, 113-8431
Tokyo
Japan
Novartis Investigative Site
Recruiting
Chuo ku, 104 0045
Tokyo
Japan
Novartis Investigative Site
Recruiting
Minato ku, 105-8470
Tokyo
Japan
Novartis Investigative Site
Recruiting
Wakayama-city, 641-8510
Wakayama
Japan
Novartis Investigative Site
Recruiting
Ube-city, 755-0241
Yamaguchi
Japan
Novartis Investigative Site
Recruiting
Fukuoka, 810-8563
-
Japan
Novartis Investigative Site
Recruiting
Osaka, 545-8586
-
Japan
Jordan
Novartis Investigative Site
Recruiting
Amman, 11941
-
Jordan
Korea, Republic of
Novartis Investigative Site
Recruiting
Cheongju si, 28644
Chungcheongbuk Do
Korea, Republic of
Novartis Investigative Site
Recruiting
Jeollanam-do, 58128
Korea
Korea, Republic of
Novartis Investigative Site
Recruiting
Seoul, 08308
Korea
Korea, Republic of
Novartis Investigative Site
Recruiting
Busan, 612-896
-
Korea, Republic of
Novartis Investigative Site
Recruiting
Seoul, 03080
-
Korea, Republic of
Novartis Investigative Site
Recruiting
Seoul, 03722
-
Korea, Republic of
Novartis Investigative Site
Recruiting
Seoul, 05505
-
Korea, Republic of
Lebanon
Novartis Investigative Site
Withdrawn
El Chouf, 1503201002
LBN
Lebanon
Novartis Investigative Site
Recruiting
Ashrafieh, 166830
-
Lebanon
Novartis Investigative Site
Recruiting
Beirut,
-
Lebanon
Novartis Investigative Site
Recruiting
El Metn,
-
Lebanon
Novartis Investigative Site
Recruiting
Saida, 652
-
Lebanon
Novartis Investigative Site
Recruiting
Tripoli, 1434
-
Lebanon
Malaysia
Novartis Investigative Site
Recruiting
Kuching, 93586
Sarawak
Malaysia
Novartis Investigative Site
Recruiting
Kuala Lumpur, 59100
-
Malaysia
Novartis Investigative Site
Recruiting
Pulau Pinang, 10990
-
Malaysia
Mexico
Novartis Investigative Site
Recruiting
Mexico, 06700
-
Mexico
Novartis Investigative Site
Recruiting
Puebla, 72530
-
Mexico
Norway
Novartis Investigative Site
Recruiting
Bergen, 5021
-
Norway
Novartis Investigative Site
Recruiting
Drammen, 3004
-
Norway
Novartis Investigative Site
Recruiting
Oslo, 0424
-
Norway
Novartis Investigative Site
Recruiting
Tromsø, 9038
-
Norway
Panama
Novartis Investigative Site
Recruiting
Panama City, 0801
-
Panama
Peru
Novartis Investigative Site
Recruiting
San Borja, 41
Lima
Peru
Novartis Investigative Site
Recruiting
Surquillo, 34
Lima
Peru
Novartis Investigative Site
Recruiting
Lima, Lima 31
-
Peru
Philippines
Novartis Investigative Site
Recruiting
Davao City, 8000
Davao
Philippines
Novartis Investigative Site
Recruiting
Taguig City, 1634
Metro Manila
Philippines
Novartis Investigative Site
Recruiting
Makati City, 1229
-
Philippines
Novartis Investigative Site
Recruiting
Quezon City, 1100
-
Philippines
Novartis Investigative Site
Withdrawn
Quezon City, 1102
-
Philippines
Poland
Novartis Investigative Site
Recruiting
Krakow, 31-826
Ma3opolska
Poland
Novartis Investigative Site
Recruiting
Brzozow, 36-200
-
Poland
Novartis Investigative Site
Recruiting
Konin, 62 500
-
Poland
Novartis Investigative Site
Recruiting
Olsztyn, 10-288
-
Poland
Novartis Investigative Site
Recruiting
Poznan, 60-693
-
Poland
Novartis Investigative Site
Recruiting
Rzeszow, 35-021
-
Poland
Novartis Investigative Site
Recruiting
Warszawa, 02 781
-
Poland
Portugal
Novartis Investigative Site
Recruiting
Lisboa, 1769-001
-
Portugal
Novartis Investigative Site
Recruiting
Matosinhos, 4454 513
-
Portugal
Novartis Investigative Site
Recruiting
Porto, 4100-180
-
Portugal
Romania
Novartis Investigative Site
Recruiting
Floresti, 407280
Cluj
Romania
Novartis Investigative Site
Recruiting
Craiova, 200347
Dolj
Romania
Novartis Investigative Site
Recruiting
Bucharest, 022328
-
Romania
Novartis Investigative Site
Recruiting
Bucuresti, 010991
-
Romania
Novartis Investigative Site
Recruiting
Cluj-Napoca, 400124
-
Romania
Novartis Investigative Site
Recruiting
Iasi, 700483
-
Romania
Novartis Investigative Site
Recruiting
Timisoara, 300239
-
Romania
Russian Federation
Novartis Investigative Site
Recruiting
Arkhangelsk, 163045
-
Russian Federation
Novartis Investigative Site
Recruiting
Kaliningrad, 236006
-
Russian Federation
Novartis Investigative Site
Recruiting
Moscow, 143423
-
Russian Federation
Novartis Investigative Site
Withdrawn
Nizhny Novgorod, 603137
-
Russian Federation
Novartis Investigative Site
Recruiting
Obninsk, 249036
-
Russian Federation
Novartis Investigative Site
Recruiting
Omsk, 644013
-
Russian Federation
Novartis Investigative Site
Recruiting
Pushkin Saint Petersburg, 196603
-
Russian Federation
Novartis Investigative Site
Recruiting
Ryazan, 390011
-
Russian Federation
Novartis Investigative Site
Recruiting
Saint Petersburg, 197022
-
Russian Federation
Novartis Investigative Site
Recruiting
St Petersburg, 192148
-
Russian Federation
Novartis Investigative Site
Recruiting
St Petersburg, 197758
-
Russian Federation
Novartis Investigative Site
Recruiting
Yaroslavl, 150054
-
Russian Federation
Slovenia
Novartis Investigative Site
Recruiting
Ljubljana, 1000
-
Slovenia
South Africa
Novartis Investigative Site
Recruiting
George, 6530
Western Cape
South Africa
Novartis Investigative Site
Recruiting
Pretoria, 0001
-
South Africa
Spain
Novartis Investigative Site
Recruiting
Cordoba, 14004
Andalucia
Spain
Novartis Investigative Site
Recruiting
Sevilla, 41013
Andalucia
Spain
Novartis Investigative Site
Recruiting
Santander, 39008
Cantabria
Spain
Novartis Investigative Site
Recruiting
Badalona, 08916
Catalunya
Spain
Novartis Investigative Site
Recruiting
Barcelona, 08036
Catalunya
Spain
Novartis Investigative Site
Recruiting
Valencia, 46010
Comunidad Valenciana
Spain
Novartis Investigative Site
Recruiting
Santiago de Compostela, 15706
Galicia
Spain
Novartis Investigative Site
Recruiting
La Laguna, 38320
Santa Cruz De Tenerife
Spain
Novartis Investigative Site
Recruiting
Barcelona, 08907
-
Spain
Novartis Investigative Site
Recruiting
Madrid, 28009
-
Spain
Novartis Investigative Site
Recruiting
Madrid, 28035
-
Spain
Novartis Investigative Site
Recruiting
Madrid, 28041
-
Spain
Novartis Investigative Site
Recruiting
Madrid, 28222
-
Spain
Switzerland
Novartis Investigative Site
Recruiting
Bern, 3010
-
Switzerland
Novartis Investigative Site
Recruiting
Fribourg, 1708
-
Switzerland
Novartis Investigative Site
Recruiting
Geneve 14, CH 1211
-
Switzerland
Taiwan
Novartis Investigative Site
Recruiting
Changhua, 50006
-
Taiwan
Novartis Investigative Site
Recruiting
Hualien, 970
-
Taiwan
Novartis Investigative Site
Recruiting
Kaohsiung City, 83301
-
Taiwan
Novartis Investigative Site
Recruiting
Kaohsiung, 82445
-
Taiwan
Novartis Investigative Site
Withdrawn
Kaoshiung, 80756
-
Taiwan
Novartis Investigative Site
Recruiting
Taichung, 40447
-
Taiwan
Novartis Investigative Site
Recruiting
Taichung, 40705
-
Taiwan
Novartis Investigative Site
Recruiting
Taipei, 10002
-
Taiwan
Novartis Investigative Site
Recruiting
Taipei, 11217
-
Taiwan
Novartis Investigative Site
Recruiting
Taoyuan, 33305
-
Taiwan
Thailand
Novartis Investigative Site
Recruiting
Songkhla, 90110
Hat Yai
Thailand
Novartis Investigative Site
Recruiting
Khon Kaen, 40002
THA
Thailand
Novartis Investigative Site
Recruiting
Bangkok, 10300
-
Thailand
Novartis Investigative Site
Recruiting
Bangkok, 10330
-
Thailand
Novartis Investigative Site
Recruiting
Bangkok, 10400
-
Thailand
Novartis Investigative Site
Recruiting
Chaingmai, 50200
-
Thailand
Turkey
Novartis Investigative Site
Recruiting
Adana, 01250
-
Turkey
Novartis Investigative Site
Recruiting
Ankara, 06460
-
Turkey
Novartis Investigative Site
Recruiting
Istanbul, 34303
-
Turkey
Novartis Investigative Site
Recruiting
Izmir,
-
Turkey
Novartis Investigative Site
Recruiting
Pendik / Istanbul, 34899
-
Turkey
United Kingdom
Novartis Investigative Site
Recruiting
Cambridge, CB2 0QQ
Cambrigdeshire
United Kingdom
Novartis Investigative Site
Recruiting
Truro, TR1 3LJ
Cornwall
United Kingdom
Novartis Investigative Site
Recruiting
Cheltenham, GL53 7AN
Gloucestershire
United Kingdom
Novartis Investigative Site
Recruiting
Wirral, CH63 4JY
Merseyside
United Kingdom
Novartis Investigative Site
Recruiting
Ipswich, IP4 5PD
Suffolk
United Kingdom
Novartis Investigative Site
Recruiting
Guildford, GU2 7XX
Surrey
United Kingdom
Novartis Investigative Site
Withdrawn
Rhyl, LL18 5UJ
Wales
United Kingdom
Novartis Investigative Site
Recruiting
Birmingham, B9 5SS
-
United Kingdom
Novartis Investigative Site
Recruiting
Bristol, BS2 8HN
-
United Kingdom
Novartis Investigative Site
Recruiting
Leicester, LE1 5WW
-
United Kingdom
Novartis Investigative Site
Recruiting
London, EC14 7BE
-
United Kingdom
Novartis Investigative Site
Recruiting
London, NW3 2QG
-
United Kingdom
Novartis Investigative Site
Withdrawn
Norwich, NR4 7UY
-
United Kingdom
Novartis Investigative Site
Recruiting
Nottingham, NG5 1PB
-
United Kingdom
Novartis Investigative Site
Recruiting
Oxford, OX3 7LJ
-
United Kingdom
Novartis Investigative Site
Recruiting
Preston, PR2 9HT
-
United Kingdom
Novartis Investigative Site
Withdrawn
Scunthorpe, DN15 7GB
-
United Kingdom
Novartis Investigative Site
Recruiting
Stoke-on-Trent, ST4 6QG
-
United Kingdom
Vietnam
Novartis Investigative Site
Recruiting
Hanoi, 100000
-
Vietnam

Contacts

Name: 
Novartis Pharmaceuticals
Phone: 
1-888-669-6682
Name: 
Novartis Pharmaceuticals
Phone: 
+41613241111
Email: 

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