Last Update: Sep 01, 2023
Long Term observAtional, Prospective, Multicenter Study to Collect iN a Real-world populatIon Data on the treatMent Pattern of secukinumAb in Adult Patients With Moderate to Severe Hidradenitis Suppurativa (HS) (ANIMA)
ClinicalTrials.gov Identifier:
Novartis Reference Number:CAIN457MDE01
All compounds are either investigational or being studied for (a) new use(s). Efficacy and safety have not been established. There is no guarantee that they will become commercially available for the use(s) under investigation.

Study Description

The purpose of this observational, prospective, non-interventional, multicenter, open-label, single arm study in Hidradenitis suppurativa (HS) is to assess the treatment pattern of secukinumab in a flexible dosing regimen and decision influencing factors for flexible dosing in a real-world population over 2 years.

Hidradenitis Suppurativa
Recruiting
600
Aug 10, 2023
Dec 22, 2026
All
18 Years - 99 Years (Adult, Older Adult)

Interventions

Other

secukinumab

Prospective observational study. There is no treatment allocation. Patients administered secukinumab by prescription and administered according to the SmPC.

Eligibility Criteria

Inclusion Criteria:

Patients eligible for inclusion in this study have to fulfill all of the following criteria at enrollment:

Patients who provide written informed consent to participate in the study
Male and female patients with ≥18 years of age
Diagnosis of clinically unequivocal moderate to severe HS
Patients for whom a therapy with secukinumab is medically indicated
Documented decision for treatment with marketed secukinumab regardless of this noninterventional study
Treatment with secukinumab according to the latest version of SmPC
Initial treatment with marketed secukinumab planned for up to 1 week before the baseline visit

Exclusion Criteria:

Patients fulfilling any of the following criteria at enrollment are not eligible for inclusion in this study. No additional exclusions may be applied by the investigator, in order to ensure that the study population will be representative of all eligible patients:

Patients who have any contraindications, such as a history of or active inflammatory bowel disease (Crohn´s disease, ulcerative colitis), and are not eligible for treatment with secukinumab according to the SmPC
Any medical or psychological condition in the treating physician's opinion which may prevent the patient from the study participation
Simultaneous participation in any investigational trial or simultaneous participation in another Novartis-sponsored non-interventional study with secukinumab
Previous exposure to IL-17 inhibitors
For biologic-naïve patients, previous exposure to another biologic drug, such as anti-TNF-α inhibitors

Study Location

Novartis Investigative Site

Recruiting

Geilenkirchen,52511,Germany

Novartis Investigative Site

Recruiting

Bochum,44791,Germany

Novartis Investigative Site

Recruiting

Nuernberg,90402,Germany

Novartis Investigative Site

Recruiting

Gera,07548,Germany

Novartis Investigative Site

Recruiting

Buxtehude,21614,Germany

Novartis Investigative Site

Recruiting

Remscheid,42897,Germany

Novartis Investigative Site

Recruiting

Hasfurt,97437,Germany

Novartis Investigative Site

Recruiting

Chemnitz,09113,Germany

Novartis Investigative Site

Recruiting

Selters,56242,Germany

Novartis Investigative Site

Recruiting

Karlsruhe,76133,Germany

Novartis Investigative Site

Recruiting

Dresden,01309,Germany

Novartis Investigative Site

Recruiting

Unna,59423,Germany

Novartis Investigative Site

Recruiting

Lauf,91207,Germany

Novartis Investigative Site

Recruiting

Duren,52349,Germany

Novartis Investigative Site

Recruiting

Wittlich,54316,Germany

Novartis Investigative Site

Recruiting

Marburg,35043,Germany

Novartis Investigative Site

Recruiting

Erlangen,91054,Germany

Novartis Investigative Site

Recruiting

Wuppertal,42103,Germany

Novartis Investigative Site

Recruiting

Moenchengladbach,41063,Germany

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