Our longstanding commitment to understanding the underlying molecular basis of disease not only deepens our knowledge of the biology, it enables us to turn scientific insights into medical breakthroughs. Research at NIBR comprises a broad range of areas from which postdoctoral scholars and their mentors create research projects. Ideally, these projects take advantage of the rich and unique drug discovery environment, including access to sophisticated research tools. Projects are often interdisciplinary in nature, combining biology and chemistry and/or computational approaches, or bridging different disease areas.
Cancer Biology
Research in cancer biology focuses on understanding genetic mechanisms of therapeutic resistance and pathogenic molecular mechanisms..
Chemistry
Research in chemistry encompasses a broad range of areas, including chemical biology, modulation of RNA function, biochemical transformations....
Computational Sciences
Computational sciences span a broad range of research in computational chemistry and informatics...
Immunology
Our research focuses on understanding immune pathways important in disease pathophysiology. We focus on autoimmune and inflammatory diseases...
Musculoskeletal
Our research focuses on muscle wasting associated with disuse (e.g., from cancer, chronic obstructive pulmonary disease, and aging), as well as tendon...
Neurobiology
Our research builds on the latest advances in human and zebrafish genetics to probe pathways underlying the pathophysiology of...
Pathways Biology
NIBR focuses on core signaling pathways as an organizing principle to further understanding of disease mechanisms and identify novel targets...
Regenerative Medicine
Current research areas include stem cell biology and tissue/organ regeneration, in particular understanding the molecular mechanisms...
Structural Biology
To gain understanding of molecular mechanisms relevant to disease biology, we use biophysical techniques such as X-ray crystallography, NMR...