350147BR
Aug 09, 2022
Switzerland

Job Description

85 quantitative scientists in Novartis are supporting more than 80 clinical development projects in 10 therapeutic areas every day. Come and join an industry leader where you will have the opportunity to provide quantitative sciences support in late-stage drug development.

Novartis has an exciting new opportunity for an Executive /Senior Director Pharmacometrics to lead strategy for clinical development programs and manage a portfolio, determine the strategic direction of the development and application of Pharmacometrics methodologies.

You will be responsible for leading and optimizing the design and implementation of Pharmacometrics methodologies that help optimize drug development programs across the development organization, lead and optimize the contribution from drug development scientists by consulting with Novartis Institutes for Biomedical Research & Development and Global Medical Affairs partners. You are expected to possess a thorough understanding of clinical development and operational implications and exhibit exemplary leadership skills.

Your responsibilities will include:
• Ensure PMX strategic contributions to, and influence the direction of, robust clinical development plans and their execution.
• Lead in the development of strategic quantitative frameworks for clinical programs in close collaboration with senior management/Development Units as required.
• Represent Pharmacometrics science for clinical/submission teams and at regulatory interactions.
• Liaise with senior management to influence and negotiate on drug development innovation and clinical development plans with particular emphasis on MIDD strategies.
• Take a leadership role in collaboration with partners from other functions to ensure a coherent Pharmacometrics contribution to the development strategy.
• As partner to senior clinical and scientific leadership, drive and shape strategic Pharmacometrics input and excellence to drug development across multiple therapeutic or disease areas/indications.
• Anticipate Development Unit needs based on in-depth understanding of the relevant Pharmacometrics issues.
• Propose or lead functional or cross-functional initiatives requiring coordination of diverse of team members.
• Independently represent PMX in due-diligence teams for high-complexity in-licensing opportunities and drive toward steps required to implement a possible deal.
• Mentor and develop next generation pharmacometricians.

Diversity & Inclusion / EEO

Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve.

Minimum Requirements

What you'll bring to the role:
• Ph.D. in pharmacology, biology, engineering, mathematics, statistics, computational science, or a field with significant modeling-related content (or equivalent)
• 12+ years of experience in positions with ever increasing relevant responsibilities; 10+ years in applying, innovating, and mentoring model based methods in pre-clinical and clinical drug development.
• Expert knowledge and evidence of hands-on experience in the application of Pharmacometrics methods to drug development
• Evidence of consulting skill in the drug development context, i.e. within project teams and management boards; experience interacting with regulatory agencies.
• Clinical, pharmacological and therapeutic knowledge in one or more disease areas
• Proven expert scientific leadership skills demonstrated in facilitating and optimizing the clinical development strategy.
• Excellent record of leading the interface to regulatory agencies.
• Expert knowledge of drug development and HA guidelines relevant to all areas of Pharmacometrics in clinical drug development.
• Excellent communication and presentation skills and in particular the ability to effectively represent Pharmacometrics issues to a wide range of target audiences.
• Strong leadership and mentoring skills. Drives and motivates teams and peers.

WHY NOVARTIS?

766 million lives were touched by Novartis medicines in 2020, and while we’re proud of this, we know there is so much more we could do to help improve and extend people’s lives.

We believe new insights, perspectives and ground-breaking solutions can be found at the intersection of medical science and digital innovation. That a diverse, equitable and inclusive environment inspires new ways of working.

We believe our potential can thrive and grow in an unbossed culture underpinned by integrity, curiosity and flexibility. And we can reinvent what's possible, when we collaborate with courage to aggressively and ambitiously tackle the world’s toughest medical challenges. Because the greatest risk in life, is the risk of never trying!

Imagine what you could do here at Novartis!
Global Drug Development
CD&A GDD
Switzerland
Basel
Research & Development
Full Time
Regular
No
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350147BR

Executive/Senior Director Pharmacometrics

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