Aug 12, 2022

Job Description

6000! This is the number of associates in the Novartis Institutes for BioMedical Research (NIBR). This division is the innovation engine of Novartis, focusing on new technologies that have the potential to help produce therapeutic breakthroughs for patients. The Biotherapeutic Engineering and Gene Therapy (BEGT) group is a part of the NIBR Biologics Center (NBC). BEGT drives a diverse portfolio of modalities including therapeutic proteins, multi-specific antibodies, CAR-T, RNAi therapeutics, AAV and lentiviral vectors. NBC works collaboratively with disease area groups to broaden the use of biologics in therapeutic applications.

We have an opportunity for a Research Scientist to join the team in Cambridge, MA. As a scientist, you work in a dynamic team of passionate scientists to develop primary and immortalized cell culture systems to evaluate RNA interference (RNAi) for potency, stability, and specificity to study hepatic and extra hepatic pathological implications. As a key contributor in a dynamic and multidisciplinary team, you will be involved in the development of RNAi platforms, act as a project team lead and drive innovation in close collaboration with partner teams at NIBR.
What you’ll be doing: Your responsibilities include, but are not limited to:
• Perform cell culture experiments in primary cells and immortalized cell lines.
• Develop and explore new in vitro screen assays and assays to characterize siRNAs for activity, specificity and uptake.
• Conduct molecular biology assays to support in vitro studies such as qPCR, cloning, ELISA.
• Support lab maintenance and logistics from reagent inventory to distribution to reagent preparation.
• Explore new technologies and find creative solutions to optimize current platform and utilize robotic to facilitate high throughput.

Diversity & Inclusion / EEO

The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Minimum Requirements

What you’ll bring to the role:
• B.S in in molecular/cell biology or biochemistry with at least 2+ years of hands-on experience or M.S. in relevant field +1 year hands-on experience
• Experienced in mammalian cell culture handling
• Hands-on experience in molecular biology assays including qPCR, cloning, ELISA, and functional assays.
• Detail-oriented and well-organized with the ability to thrive in a team and be comfortable working on and prioritizing multiple projects.
• Excellent communication skills and ability to work in a collaborative setting

Why Novartis
766 million lives were touched by Novartis medicines in 2021, and while we’re proud of this, we know there is so much more we could do to help improve and extend people’s lives.

We believe new insights, perspectives and ground-breaking solutions can be found at the intersection of medical science and digital innovation. That a diverse, equitable and inclusive environment inspires new ways of working.

We believe our potential can thrive and grow in an unbossed culture underpinned by integrity, curiosity and flexibility. And we can reinvent what's possible, when we collaborate with courage to aggressively and ambitiously tackle the world’s toughest medical challenges. Because the greatest risk in life, is the risk of never trying!
Imagine what you could do here at Novartis!

Commitment to Diversity & Inclusion:
Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve.

Accessibility and Reasonable Accommodations: The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please send an e-mail to [email protected] call +1 (877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.

While Novartis does not require vaccination at this time, for certain Novartis sites in the US all associates and candidates may be required to either upload an image of their COVID-19 vaccine card demonstrating proof of full vaccination for COVID-19 (or other similar evidence of vaccination) or proof of a negative COVID-19 test taken by the associate or candidate within the past seven days to enter any of our sites and/or customer office or healthcare facility, as well as prior to participating in other work related off-site meetings. Employees working in customer-facing roles must adhere to and comply with customers’ (such as hospitals, physician offices, etc.) credentialing guidelines, which may require vaccination. As required by applicable law, Novartis will consider requests for reasonable accommodation for those unable to be vaccinated. This requirement is subject to applicable state and local laws and may not be applicable to employees working in certain jurisdictions. Please send accommodation requests to [email protected].
Cambridge, MA
Research & Development
Full Time
careers default image

Research Scientist, Cell & Gene Therapy

Apply to Job Access Job Account