Jul 26, 2022

Job Description

60 million! That is how many people are affected globally by glaucoma. This can lead to progressive damage to retinal ganglion cells and the optic nerve and may lead to blindness.

At Novartis, we are developing new therapies to help control glaucoma disease progression by lowering eye pressure and by protecting retinal neurons to treat this silent thief of sight.

We are looking for an experienced scientist proficient in in vitro / ex-vivo laboratory skills to join our Ophthalmology department to support the discovery and development of innovative glaucoma treatments.

What you’ll be doing:

• Developing, optimizing, and applying in vitro / ex vivo assays to support the discovery, validation & characterization of novel glaucoma therapies, and stay current on literature and technological advances
• Handling / processing of ex-vivo tissues for pharmacodynamics / biomarker assessments
• Independently perform experiments, troubleshoot issues, analyze data, generate reports, and present data at internal forums
• Collaborate with cross-function al teams on target discovery and drug development projects
• Assist in general laboratory maintenance

Diversity & Inclusion / EEO

The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Minimum Requirements

What you'll bring to the role:

• MS or BS in Biology or related field with 3-5+ years of full time academic or industry laboratory experience. The level of the position will be commensurate with experience.
• Hands-on experience in culturing primary cells / stem cells / iPSC-derived cells, immunocytochemistry, and fluorescent microscopy imaging
• Demonstrated proficiency in a broad range of techniques across pharmacology / molecular biology / protein biochemistry / cellular assays & analysis [such as cloning, PCR, viral vector transfection/transduction, CRISPR gene editing, receptor-ligand interactions, Western blotting, immunoprecipitation, cell-based assays, flow cytometry, cell sorting, ELISA]
• Strong attention to detail, demonstrated ability to execute experiments with rigor, and maintain clear and complete records of lab work
• Highly motivated self-starter and problem-solver, curious to expand existing skills & develop new ones
• Demonstrated capability to work independently, thrive in a fast-paced matrix research environment capacity, to adapt and respond timely to needs of research & personnel, and strong verbal and written communication skills

• Training in Ophthalmology, Neuroscience, Immunology, Matrix or Cell biology or related fields
• Familiarity with ocular perfusion culture, tissue microdissection, explant culture, complex phenotypic assays, and cell culture systems
• Proficient in using biological databases and online resources / tools to analyze protein, DNA, and RNA sequences
• Experience with high throughput screening, immunohistochemistry, high content imaging

Why consider Novartis?

769 million. That’s how many lives our products touch. At Novartis, being there when and how it matters most for our patients and customers allows us to live our purpose and help bring maximum impact to health outcomes.

Furthering our commitment to transforming medicine for patients, Novartis is embarking on an ambitious and exciting journey to reinvent how we use technology, data and customer insights to better serve our consumer’s needs and put them on a path to better health. This includes taking bold approaches that begin with a customer-centric mindset and harness the power of today’s digital and data-driven healthcare revolution to continue to improve and extend even more people’s lives.

• Do you want to help people understand their disease and how to seek out the proper treatment for it?
• Do you want to support patients in order to achieve the best possible outcomes?
• Do you want to deliver a leading customer experience at all touchpoints?
• Do you want to be at the forefront of leveraging today’s technology advances to create tomorrow’s healthcare innovations?

We believe the answers are found when curious, adventurous, and collaborative people like you are brought together in an inspiring environment. Where you’re given opportunities to utilize the power of digital and data to individualize and maximize interactions with customers. Where you’re empowered to not fear failure when taking smart risks. And most importantly, where you’re surrounded by people who share your determination to tackle the world’s toughest medical challenges.

Commitment to Diversity & Inclusion:
Novartis is committed to building an outstanding, inclusive work environment and diverse team’s representative of the patients and communities we serve.

Join our Novartis Network:
If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network
Cambridge, MA
Research & Development
Full Time
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Senior Scientist, In Vitro/Ex Vivo - Ophthalmology

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