Jul 20, 2022

Job Description

14! That is how many disease areas this Senior Scientist may support across the Novartis Institutes of Biomedical Research (NIBR).

Our Global Genetically Engineered Models (GEM) Team within Comparative Medicine (CM) supports the expansion of animal science, preclinical care, and research model development furthering research across the world. We are the innovation incubator within in vivo pre-clinical research and are the central partner for in vivo scientific input, organizing and performing all in vivo activities.

The Senior Scientist role is a highly technical and/or specialized professional position responsible for supporting 14 disease areas including oncology, neuroscience and cardiovascular medicine, providing high quality & consistent in vivo technical research support within our multi-building, multi-discipline research program. The role is primarily lab-based and on-site.

Your key responsibilities will include, but not limited to:
•Microinjection of CRISPR reagents and plasmids as well as embryo transfer and other relevant surgical procedures. Sperm and embryo cryopreservation, IVF and all supporting activities
•Other gene transfer techniques, including electroporation
•Contribute to implementation of novel technologies and approaches to genome engineering of animals
•Responsible for ensuring compliance with all institutional and regulatory protocols, policies, and guidelines.
•Regularly complete literature reviews to maintain familiarity with the latest technologies focused on improving current in vivo disease modeling.
•Conduct presentations of data and results to the Genetically Engineered Models group and project teams.
•Other duties and responsibilities as may be required.

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Diversity & Inclusion / EEO

The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Minimum Requirements

What you’ll bring to the role:

• Bachelor’s degree in Biological Sciences (Genetics, Development, Molecular Biology or related fields) with 3+ years of hands-on experience with laboratory techniques necessary for creating new animal models. The level of the position will be commensurate with experience.
• Preferred experience working in a molecular biology laboratory and/or rodent microinjection laboratory
• Detail oriented, knowledgeable around the IACUC/AWC compliance, regulation, able to utilize paper and electronic study protocols, document experiments in laboratory notebook
• Advanced computer skills using Excel, OneDrive, Word and Outlook, being able to collect and record research data having the ability and knowledge to review documentation as a quality control
• Working knowledge of federal, state, local (Animal Welfare) laws, departmental SOP’s and Good Laboratory Practices
• Must be able to lift 50 lbs. Must be able to work from a standing or sitting position for prolonged time periods and perform repetitive motion tasks.

• Master’s degree in Biological Sciences with 5+ years of hands-on experience and a significant microinjection record of accomplishment as well as proficiency with relevant animal surgical procedures
• Basic or advanced understanding of CRISPR technology and experience with CRISPR-mediated animal model generation
• Excellent organizational, written and oral communication skills

Why Novartis?

766 million lives were touched by Novartis medicines in 2021, and while we’re proud of this, we know there is so much more we could do to help improve and extend people’s lives.

We believe new insights, perspectives and ground-breaking solutions can be found at the intersection of medical science and digital innovation. That a diverse, equitable and inclusive environment inspires new ways of working.

We believe our potential can thrive and grow in an unbossed culture underpinned by integrity, curiosity and flexibility. And we can reinvent what's possible, when we collaborate with courage to aggressively and ambitiously tackle the world’s toughest medical challenges. Because the greatest risk in life, is the risk of never trying!

Imagine what you could do here at Novartis!

Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve.

Accessibility and Reasonable Accommodations: Individuals in need of a reasonable accommodation due to a medical condition or disability for any part of the application process, or to perform the essential functions of a position, please send an e-mail to [email protected] or call +1 (877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.

Vaccine Policy: While Novartis does not require vaccination at this time, for certain Novartis sites in the US all associates and candidates may be required to either upload an image of their COVID-19 vaccine card demonstrating proof of full vaccination for COVID-19 (or other similar evidence of vaccination) or proof of a negative COVID-19 test taken by the associate or candidate within the past seven days to enter any of our sites and/or customer office or healthcare facility, as well as prior to participating in other work related off-site meetings. Employees working in customer-facing roles must adhere to and comply with customers’ (such as hospitals, physician offices, etc.) credentialing guidelines, which may require vaccination. As required by applicable law, Novartis will consider requests for reasonable accommodation for those unable to be vaccinated. This requirement is subject to applicable state and local laws and may not be applicable to employees working in certain jurisdictions. Please send accommodation requests to [email protected].
Cambridge, MA
Research & Development
Full Time
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Microinjectionist, Senior Scientist - Comparative Medicine

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