Jul 18, 2022

Job Description

1 Global Discovery Chemistry community, working across seven disease areas at the Novartis Institutes for BioMedical Research (NIBR), is seeking a creative and curious chromatographer with expertise in SFC and HPLC purification processes to join the Global Discovery Chemistry Analytics and Separations Group in Cambridge, MA.

Here, we value your ideas, personal growth, and career aspirations; you will be surrounded by and learn from curious colleagues across multiple disciplines; you will have opportunities to explore the power of cutting-edge science and technology.

In partnership with research and discovery chemistry, the Separations Team confronts the challenging task of purifying and characterizing molecules ranging from traditional small molecules to novel conjugated biotherapeutics. We are looking for individuals with expertise in providing solutions to challenging analytical, separations, and purifications problems in drug discovery. You will work in a highly collaborative team environment, developing analytical and preparative methods for the analysis and purification of achiral and chiral drug discovery molecules.

Your responsibilities will include:

- Support of medicinal chemistry projects across a variety of disease areas and purification of chemically diverse substrates that include small molecules, peptides, and conjugated biotherapeutics.

- A specific focus on analytical method development and preparative chromatography techniques, including SFC-MS, NP-HPLC, and RP-HPLC-MS.

- Utilize additional analytical methods such as SEC, HIC, NMR, MS/MS, and Tecan automation.

- Juggle several parallel workflows while communicating and collaborating with chemists.

- Work closely with medicinal and analytical chemists as well as scientists from a diverse range of disciplines within NIBR.

- Identify and pursue new projects and technologies that directly impact drug discovery research.

Diversity & Inclusion / EEO

The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Minimum Requirements

What you will bring to the role:

- Expertise in modern chromatography methods, technologies, and in-depth experience with chromatography and preparative SFC and HPLC purifications.

- Strong technical skills in the operation and maintenance of chromatographic instrumentation and software.

- Expertise with Tecan liquid handling and Freedom Evoware software.

- Strong skills in data analysis, interpretation, management, and software skills.

- Strong interpersonal skills and the ability to work collaboratively in a team environment.

Desirable requirements:

- A Bachelors or Masters in Chemistry or Chemistry-related field with at least 5 years of relevant industry experience purifying compounds in a drug discovery environment.

- Specific experience in operating SFC and HPLC analytical and preparative instrumentation.

Why Novartis?

766 million lives were touched by Novartis medicines in 2021, and while we’re proud of this, we know there is so much more we could do to help improve and extend people’s lives.

We believe new insights, perspectives and ground-breaking solutions can be found at the intersection of medical science and digital innovation. That a diverse, equitable and inclusive environment inspires new ways of working.

We believe our potential can thrive and grow in an unbossed culture underpinned by integrity, curiosity and flexibility. And we can reinvent what's possible, when we collaborate with courage to aggressively and ambitiously tackle the world’s toughest medical challenges. Because the greatest risk in life, is the risk of never trying!

Imagine what you could do here at Novartis!

Commitment to Diversity and Inclusion:

Novartis is committed to building an outstanding, inclusive work environment and diverse team’s representative of the patients and communities we serve.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.
Global Discovery Chemistry
Cambridge, MA
Research & Development
Full Time
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Analytics and Separations Scientist

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