Jul 08, 2022

Job Description

6500! That’s the number of associates in the Novartis Institutes for BioMedical Research (NIBR). This division is the innovation engine of Novartis, focusing on powerful new technologies that have the potential to help produce therapeutic breakthroughs for patients.

Applications are invited for a Research Scientist to carry out cutting-edge oncology drug discovery pharmacology research. We seek an experienced, motivated and ambitious individual with a passion for in vivo oncology research. You will join the Radioligand Therapy team to develop and validate novel targets in our world leading Oncology portfolio. The position is based at the Novartis Institutes of BioMedical Research (www.nibr.com) in Basel, Switzerland.

The ideal candidate should have a passion for working with rodents and a drive to perform in vivo oncology pharmacology studies including micro-surgeries, compound administration and preparation of samples for ex vivo analysis. Hands-on background performing small animal imaging modalities such as PET/SPECT/uCT or in cell biology techniques is a plus. The successful candidate will work collaboratively as an integral part of global projects and be an active member of lab and project teams.

Responsibilities include but are not limited to:
• Develop and characterize novel in vivo oncology models
• Perform efficacy studies with cutting edge radioligand therapies
• Perform biodistribution studies and metabolites analysis
• Perform pre-clinical imaging studies including PET/SPECT/uCT
• Design, perform and evaluate various in vitro and ex vivo assays (e.g. cell culture, transfections, IHC, proliferation assays, immunofluorescence, PCR, Western blotting, FACS)

Diversity & Inclusion / EEO

Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve.

Minimum Requirements

What you’ll bring to the role:

• Masters degree in pharmacology, cell biology, medical physics, bioengineering, biotechnology or related field or Bachelors degree with equivalent experience
• Practical work experience in biomedical research from an industry or academic laboratory
• Experience in performing animal studies (animal handling, drug application, sampling, animal welfare regulations, small laboratory animal surgery)
• Self-motivated, proactive, and able to work independently

Desirable requirements

• Knowledge and experience of standard cell biology techniques is desirable: cell culture, IHC, FACS, quantitative real-time PCR, transfection, western blotting, cell engineering etc
• Highly collaborative team player that enjoys working across multi-disciplinary teams
• Excellent organizational and communication skills
• Knowledge of cancer biology

Why Novartis?

769 million lives were touched by Novartis medicines in 2020, and while we’re proud of this, we know there is so much more we could do to help improve and extend people’s lives.

We believe new insights, perspectives and ground-breaking solutions can be found at the intersection of medical science and digital innovation. That a diverse, equitable and inclusive environment inspires new ways of working.

We believe our potential can thrive and grow in an unbossed culture underpinned by integrity, curiosity and flexibility. And we can reinvent what's possible, when we collaborate with courage to aggressively and ambitiously tackle the world’s toughest medical challenges. Because the greatest risk in life, is the risk of never trying!

Imagine what you could do here at Novartis!

* Some restrictions on flexible working options may apply and will be discussed during interview if applicable.
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Oncology NIBR
Research & Development
Full Time
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Research Scientist - in vivo pharmacology & ex vivo Biology (80-100%*)

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