Jun 09, 2022

Job Description

5600 scientists working on over 300 discovery programs in 8 disease areas focusing on 90 new molecular entities makes Novartis the premier place to develop your career as a pharmaceutical professional. If you are curious, scientifically minded, and want to positively impact society by speeding delivery of novel therapies to patients, then look no further, NIBR is the place to be. As a Scientist in the Translational Medicine PK Sciences Bioanalytical group, you will have the opportunity to make a difference. If you have a collaborative nature, a commitment to teamwork across an organization and a relentless focus on improving patient care we want you to apply.

In this laboratory-based Scientist role, you will apply your hands-on expertise to the bioanalysis of small and large molecule therapeutics, including gene therapies, cell therapies, antibody-drug conjugates, bi-trispecific/ScFV antibodies, oligonucleotides/siRNA, proteins and peptides. You will work with an elite team of scientists involved in the development and qualification of small and large molecule assays supporting pharmacokinetic, pharmacodynamic and immunogenicity studies across all phases of the drug discovery & development pipeline. Additionally, you will contribute to new technology platform evaluations to improve support for challenging new therapeutic modalities.

Your main responsibilities will include but are not limited to:

• Independently design, develop, qualify and implement bioanalytical ligand binding assays (LBAs) and qPCR (polymerase chain reaction) assays for PK, TK, PD and ADA assessment supporting various modalities such as biologics, oligonucleotides and cell and gene therapy platforms.
• Deliver high quality data within defined timelines and aligned to current industry expectations.
• Complete study sample analysis and draft the bioanalytical report in support of urgent project requests.
• Represent the bioanalytical function on project teams and present results, data interpretation, timelines etc. at project team meetings
• Collaborate with internal and external stakeholders to evaluate new bioanalytical technologies and solutions to support challenging project requests

Diversity & Inclusion / EEO

The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Minimum Requirements

What you will bring to the role:

• M.S. in chemistry, biochemistry or related field with minimum of 5 years of relevant lab experience in a pharmaceutical, CRO or related industry. BS with 10+ years of relevant experience will also be considered. PhD with 1-2 years of relevant experience.
• Hands-on experience with the development of large molecule LBAs and qPCR workflows with an understanding of a broad range of bioanalytical platforms.
• Agility and willingness to learn, implement, and teach new bioanalytical techniques to support the evolving portfolio.
• Experience managing multiple projects with competing priorities, excellent planning, organization, and time management skills including the ability to support and prioritize multiple projects, and the ability to adapt to changing priorities and deadlines.
• Strong engagement, interpersonal communication skills, presentation skills and ability to thrive in a dynamic matrixed working environment.
• Demonstrated experience in generating and documenting bioanalytical data, interpretation of bioanalytical data, and authoring study reports.

Why consider Novartis?

766 million lives were touched by Novartis medicines in 2021, and while we’re proud of this, we know there is so much more we could do to help improve and extend people’s lives. We believe new insights, perspectives and ground-breaking solutions can be found at the intersection of medical science and digital innovation. That a diverse, equitable and inclusive environment inspires new ways of working. We believe our potential can thrive and grow in an unbossed culture underpinned by integrity, curiosity and flexibility. And we can reinvent what's possible, when we collaborate with courage to aggressively and ambitiously tackle the world’s toughest medical challenges. Because the greatest risk in life, is the risk of never trying!

Imagine what you could do here at Novartis!

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Translational Medicine
Cambridge, MA
Research & Development
Full Time
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Principal Scientist I

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