346905BR
Jun 23, 2022
USA

Job Description

1 purpose! Novartis expands its early development and innovative CAR-T cell therapy capabilities for making personalized medicine accessible to more patients in need. Our therapies are being developed as transformative treatments with life-saving potential for various hematological malignancies and other oncological diseases. We look to be bold with purpose, as we reimagine medicine and lead the way in advancing scientific breakthroughs for patients.

The Senior Expert Science & Technology (Analytical Platform Development) will be a major contributor to pipeline development and implementation of novel analytical platforms for our Cell and Gene Therapy products. As a member of a high performing analytical team within the Technical Research and Development organization, the successful candidate will own current and future development projects and contribute to interdisciplinary work across the broader CGT organization. The individual will build strong relationships with multiple functions including development teams in NIBR, Quality Control and Technical Operations. The candidate should have extensive knowledge and hands-on experience in advanced analytical technologies, oncology and immunotherapy. This position requires strong leadership and management skills, prior experience in fast-paced laboratories and expertise in transcriptomics and immune cell profiling.

Your responsibilities will include, but are not limited to:

• Identify, develop and validate novel analytical assays and new GMP-compliant methodologies that enable multiplexing and rapid analytics
• Independently design, plan and perform complex molecular assays, cellular characterization, potency, multi-color flow cytometry
• Actively keeps a breast with the latest advances in next-generation technologies for cell and gene therapies
• Drive project timelines and deliverables while meeting internal quality and data integrity requirements
• Implement resolution to technical challenges, support manufacturing investigations, communicate effectively and present complex data at internal and cross-functional meetings
• Author and/or review method development reports, SOPs, validation reports and technical documents for regulatory filings
• Work according to appropriate SOPs, GMP, GLP, QM, HSE, ISEC and Novartis Guidelines and Code of Conduct




Vaccine Policy: While Novartis does not require vaccination at this time, for certain Novartis sites in the US all associates and candidates may be required to either upload an image of their COVID-19 vaccine card demonstrating proof of full vaccination for COVID-19 (or other similar evidence of vaccination) or proof of a negative COVID-19 test taken by the associate or candidate within the past seven days to enter any of our sites and/or customer office or healthcare facility, as well as prior to participating in other work related off-site meetings. Employees working in customer-facing roles must adhere to and comply with customers’ (such as hospitals, physician offices, etc.) credentialing guidelines, which may require vaccination. As required by applicable law, Novartis will consider requests for reasonable accommodation for those unable to be vaccinated. This requirement is subject to applicable state and local laws and may not be applicable to employees working in certain jurisdictions.

Diversity & Inclusion / EEO

The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Minimum Requirements

What you'll bring to the role:

• Education: PhD in Immunology, Cancer Biology, Molecular Biology or related discipline is required. Fluent English (oral and written)
• 5+ years of relevant experience including hands-on, in-depth experience in translational research and cancer immunotherapy
• Demonstrated experience with genomic workflows, next generation sequencing, cancer biomarkers, analysis of large datasets
• Scientific and technical expertise to independently plan, design, execute and troubleshoot multidimensional flow cytometry, sequencing and cell-based assays
• Experience with single cell gene expression and cell sorting is preferred
• Advanced knowledge in clustering algorithms and hierarchical models to study cell population heterogeneity in large datasets and identify novel biomarkers
• Robust scientific background and understanding of CAR-T cell biology and drug product development
• Detailed organizational skills, multi-tasking, self-motivation and attention to detail
• Drives innovation by researching relevant literature to improve existing methodologies while evaluating alternative approaches
• Excellent communication, presentation and scientific/technical writing skills
• Demonstrated ability to work collaboratively in a fast-paced team environment and quickly acquire new technical skills and knowledge

Why Novartis?

766 million lives were touched by Novartis medicines in 2021, and while we’re proud of this, we know there is so much more we could do to help improve and extend people’s lives.

We believe new insights, perspectives and ground-breaking solutions can be found at the intersection of medical science and digital innovation. That a diverse, equitable and inclusive environment inspires new ways of working.

We believe our potential can thrive and grow in an unbossed culture underpinned by integrity, curiosity and flexibility. And we can reinvent what's possible, when we collaborate with courage to aggressively and ambitiously tackle the world’s toughest medical challenges. Because the greatest risk in life, is the risk of never trying!

Imagine what you could do here at Novartis!

Please note this job description is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities that are required of the employee for this job. Duties, responsibilities and activities may change at any time with or without notice.


Accessibility and reasonable accommodations
The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please send an e-mail to [email protected] call +1 (877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.
Global Drug Development
TECHNICAL R & D GDD
USA
East Hanover, NJ
Research & Development
Full Time
Regular
No
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346905BR

Senior Expert Science & Technology (Analytical Platform Development)

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