Jun 03, 2022

Job Description

1 Global Discovery Chemistry community working across multiple disease areas at the Novartis Institutes for BioMedical Research (NIBR) is seeking a highly talented and motivated scientist to join our department in Cambridge, MA. The successful candidate will join an energizing and collaborative research organization, working alongside colleagues who are committed to improving human health through the discovery of transformative medicines.

Synthetic Technologies works to bring innovative solutions to tomorrow’s medicines. The group combines synthetic chemistry, analytical chemistry and high-throughput automation expertise to build targeted compound libraries and evaluate compounds with respect to physiochemical and ADMET properties.

We are seeking a scientist with analytical chemistry experience and an interest in laboratory automation to join to our interdisciplinary team. The successful candidate will be able to contribute to high-throughput small molecule purification workflows as well as automation support of compound plating and assays. Basic coding skills in Python and an interest in scripting methods for complex workflows would be beneficial.

Your responsibilities will include:

- Carrying out automated analytical chemistry workflows and subsequent fraction pooling and dose response plating workflows

- Perform LC-MS based analytical chemistry and purification workflows

- Support, maintenance and troubleshooting of instrumentation and laboratory robotics

- Iteration and optimization of existing automation scripts and workflows

- Design and execution of novel liquid handling and plate automation routines to enable reaction screening, library synthesis and compound profiling

- Interact effectively within a fast-paced team-oriented environment

- Communicate results and challenges effectively to both experts and non-experts

Diversity & Inclusion / EEO

The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Minimum Requirements

What you will bring to the role:

- BS or MS degree in chemistry or engineering subject area and 1-5 years of experience.

- Strong working knowledge of analytical chemistry and laboratory scale automation technologies

- Experience with optimization of laboratory workflows to increase efficiency and throughput

- Proficient with liquid handling and plate handling technologies

- Familiarity with synthetic chemistry or compound profiling assays such as high-throughput solubility, permeability or intrinsic clearance is desirable.

- Experience with Waters MassLynx software or ThermoFisher Momentum and ideally Virscidian software is desirable

- Ability to independently and safely conduct and record experiments in a laboratory setting

- Multitasking- Highly organized and excited to work in a matrix environment where there are multiple work streams to learn and become proficient in

Why consider Novartis?

766 million. That’s how many lives our products touched in 2021. And while we’re proud of that fact, in this world of digital and technological transformation, we must also ask ourselves this: how will we continue to improve and extend even more people’s lives?

We believe the answers are found when curious, courageous and collaborative people like you are brought together in an inspiring environment. Where you’re given opportunities to explore. Where you’re empowered to take smart risks, and where you’re surrounded by people who share your determination to tackle the world’s toughest medical challenges.

Imagine what you could do at Novartis!

Commitment to Diversity & Inclusion:

Novartis embraces diversity, equal opportunity and inclusion. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration, and empowers our people to unleash their full potential.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.
Global Discovery Chemistry
Cambridge, MA
Research & Development
Full Time
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Research Scientist (BS or MS), HTE Automation and Analytical Chemistry

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