May 20, 2022

Job Description

256 million! That's the number of people worldwide who are affected by glaucoma and age-related macular degeneration (AMD), two of the leading causes of vision loss in older adults. As the global population ages, eye diseases are projected to significantly increase over the coming decades.

At the Novartis Institutes for BioMedical Research (NIBR), we are focused on discovering therapies for glaucoma, AMD, and other blinding eye diseases. Our therapeutic strategy encompasses a broad range of cutting edge approaches including gene therapy, optogenetics, small molecules, antibodies, and more.

We are seeking a creative and collaborative senior level scientist to join our ophthalmology department to help discover new therapies for ocular diseases. In this role, you will be responsible for planning, executing, and analyzing in vivo pharmacology experiments with an emphasis on ocular imaging and electrophysiology readouts. You will be working in a highly matrixed, team-oriented, and collaborative environment.

Your responsibilities will include, but are not limited to:

•Identify, develop and validate new in vivo structural and/or functional read-outs to fulfill program needs.
•Plan and perform in vivo pharmacology experiments, then analyze, summarize, and clearly present that data to inform project team decisions.
•Use imaging/electrophysiology readouts to evaluate ocular structure and function in animal models. Specifically: optical coherence tomography (OCT), scanning laser ophthalmoscopy (SLO), and electroretinography (ERG) are among the many read-outs the team employs.
•Establish and validate in vivo models of ocular disease that will be used to develop new drugs.
•Apply creative solutions toward solving experimental challenges.
•Maintain an open and collaborative mindset, required to effectively operate in a highly matrixed team.

Diversity & Inclusion / EEO

The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Minimum Requirements

What you’ll bring to the role:

•Master’s or PhD degree in Neuroscience, Optics, Pharmacology, Biology, Biomedical Engineering or similar field
•5+ years of hands-on experience with designing, executing, and analyzing in vivo experiments in pre-clinical species driven by advanced in vivo structural imaging and/or electrophysiology end points. The level of the position will be commensurate with experience.
•Experience with ocular disease models is preferred, but not required.
•In-depth expertise in at least one of the following techniques: OCT, SLO, VEP, multi-electrode arrays, calcium imaging, ERG
•Experience scripting with MATLAB or similar software platforms preferred, but not required
•Ability to analyze data with high quality standards and clearly communicate the results to teams
•Ability to work independently in a fast-paced, creative, and collaborative environment
•Strong organizational skills, attention to detail, and desire to learn new techniques

799 million. That’s how many lives our products touch. And while we’re proud of that fact, in this world of digital and technological transformation, we must also ask ourselves this: how can we continue to improve and extend even more people’s lives?

We believe the answers are found when curious, courageous and collaborative people like you are brought together in an inspiring environment. Where you’re given opportunities to explore the power of digital and data. Where you’re empowered to risk failure by taking smart risks, and where you’re surrounded by people who share your determination to tackle the world’s toughest medical challenges.

We are Novartis. Join us and help us reimagine medicine.

Commitment to Diversity & Inclusion:
Novartis is committed to building an outstanding, inclusive work environment and diverse team’s representative of the patients and communities we serve.

Accessibility and reasonable accommodations:
The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please send an e-mail to [email protected] or call +1 (877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.

Join our Novartis Network: If this role is not suitable to your experience or career goals, but you wish to stay connected to learn more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network
Cambridge, MA
Research & Development
Full Time
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Senior Scientist, In Vivo Structure and Function - Ophthalmology

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