May 24, 2022

Job Description

6000! That’s the number of associates in the Novartis Institutes for BioMedical Research (NIBR). This division is the innovation engine of Novartis, focusing on powerful new technologies that have the potential to help produce therapeutic breakthroughs for patients.

We are seeking exceptional scientists, at a variety of levels, to join the Cancer Therapeutics team at the Novartis Institutes of Biomedical Research at San Diego. As part of this recruiting drive, we are seeking a highly motivated senior scientist with extensive in vitro/cell-based assay development experience to support drug screening and hit validation. The successful candidate will independently develop and implement cell-based and biochemical assays to characterize protein-protein interactions and oncogenic signaling pathways in cancer. The candidate will also leverage their expertise in biology and biochemistry to support mechanism of action studies as well as new target identification and validation in oncology.

Primary responsibilities:
• Design, optimize and implement biochemical assays to characterize protein-protein interactions and small molecule binding, including HTRF, FP, alpha screen etc. Experience with protein expression and purification is a plus.
• Perform cell-based assays to study mechanism of action of therapeutic molecules, including western blot, immunoprecipitation, ELISA, flow cytometry, qPCR, immunofluorescence, luminescence-based assays, etc.
• Experience with molecular cloning and functional genomic studies including gene knockdown and overexpression to investigate drug-target interactions is a plus.
• Data collection, analysis, documentation, and interpretation.

Diversity & Inclusion / EEO

The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Minimum Requirements

What you will bring to the role:
• B.S./M.S. degree in biology, biochemistry, or related discipline with 2-4 years of relevant research experience, ideally in an industry setting
• Experience with biochemical and/or cell-based assays used to study protein-protein interactions. Candidates are not required to have research experience in both cell-based assay and biochemical assay to be considered.
• Experience with cell culture, functional genomic studies, and routine cell-based assays in the context of oncology
• Excellent oral and written communication skills. Highly organized, detail-oriented, a team player, enthusiastic about drug discovery, with strong work ethics
• Ability to work independently in a highly interactive and fast-paced drug discovery environment. The candidate is expected to work in a matrixed multidisciplinary team and collaborate with various functional groups across NIBR.

Why Consider Novartis?
766 million lives were touched by Novartis medicines in 2021, and while we’re proud of this, we know there is so much more we could do to help improve and extend people’s lives.

We believe new insights, perspectives and ground-breaking solutions can be found at the intersection of medical science and digital innovation. That a diverse, equitable and inclusive environment inspires new ways of working.

We believe our potential can thrive and grow in an unbossed culture underpinned by integrity, curiosity, and flexibility. And we can reinvent what's possible, when we collaborate with courage to aggressively and ambitiously tackle the world’s toughest medical challenges. Because the greatest risk in life, is the risk of never trying!
Imagine what you could do here at Novartis!

Commitment to Diversity & Inclusion:
Novartis is committed to building an outstanding, inclusive work environment and diverse teams’ representative of the patients and communities we serve.

Accessibility and Reasonable Accommodations:
The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please send an e-mail to [email protected] call +1(877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.

While Novartis does not require vaccination at this time, for certain Novartis sites in the US all associates and candidates may be required to either upload an image of their COVID-19 vaccine card demonstrating proof of full vaccination for COVID-19 (or other similar evidence of vaccination) or proof of a negative COVID-19 test taken by the associate or candidate within the past seven days to enter any of our sites and/or customer office or healthcare facility, as well as prior to participating in other work related off-site meetings. Employees working in customer-facing roles must adhere to and comply with customers’ (such as hospitals, physician offices, etc.) credentialing guidelines, which may require vaccination. As required by applicable law, Novartis will consider requests for reasonable accommodation for those unable to be vaccinated. This requirement is subject to applicable state and local laws and may not be applicable to employees working in certain jurisdictions. Please send accommodation requests to [email protected]

Join our Novartis Network:
If this role is not suitable to your experience or career goals but you wish to stay connected to learn more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network
Oncology NIBR
San Diego, CA
Research & Development
Full Time
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Senior Scientist (BS/MS, lab-based) - Cancer Therapeutics

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