Oct 28, 2022

Job Description

Be part of the next breakthrough! The Novartis Institutes for BioMedical Research (NIBR), the innovation engine of Novartis, is seeking a highly motivated and collaborative Principal Scientist to lead an in vivo biology team within NIBR La Jolla’s Regenerative Medicine research group. We are dedicated to innovating the next generation of regenerative and engineered cell therapies.

As a leader of a dynamic, multidisciplinary team, you will lead the design and execution of in vivo and ex vivo studies enabling the validation and development of innovative therapeutic platforms for regenerative medicine, genome editing technology, and novel modes of delivery. This exciting role will interface with experts throughout the company in regenerative biology, protein engineering, gene therapy, and translational medicine. Focus areas will include, but are not limited to, respiratory diseases and hematology, but will expand to additional fields of biology.

Your responsibilities:

• You will assume a leadership role in the development of novel therapeutic concepts and will contribute at all stages of a project, from inception, validation, candidate selection and through to early clinical development of novel therapies
• A primary focus will be on preclinical validation of mechanisms of tissue regeneration. This may include testing of cell-based and genome-editing approaches
• Utilization of xenografts and engineered cell therapies
• Evaluation of PK/PD relationships for novel siRNA and viral delivery modalities
• You will work closely with complementary subject matter experts to develop project strategy, identify key drug discovery issues, propose and implement creative solutions, and guide teams to critical decision points.
• You will manage a team of associates with relevant, diverse expertise, as well as interact with peer teams

Diversity & Inclusion / EEO

The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Minimum Requirements

What you’ll bring to the role:
• Ph.D. with 3 to 5 years experience with in vivo biology and disease models, with supporting publication record
• Experience with a variety of in vivo disease models and methodology
• Knowledge of respiratory, neuroscience, and/or immunological models is preferred but not required
• The candidate will have a demonstrable record of accomplishment of driving research projects, including the ability to work in a collaborative environment
• Ability and willingness to learn and cross into new fields of research, expanding one’s comfort zone
• Will possess excellent oral and written communication skills and an ability to thrive in a dynamic matrix research environment.
• Creative problem-solving skills; excellent analytical, communication and organizational skills.

Why consider Novartis?

We believe the answers are found when curious, courageous and collaborative people like you are brought together in an inspiring environment. Where you’re given opportunities to explore the power of digital and data. Where you’re empowered to risk failure by taking smart risks, and where you’re surrounded by people who share your determination to tackle the world’s toughest medical challenges.

We are Novartis. Join us and help us reimagine medicine.

While Novartis does not require vaccination at this time, for certain Novartis sites in the US all associates and candidates may be required to either upload an image of their COVID-19 vaccine card demonstrating proof of full vaccination for COVID-19 (or other similar evidence of vaccination) or proof of a negative COVID-19 test taken by the associate or candidate within the past seven days to enter any of our sites and/or customer office or healthcare facility, as well as prior to participating in other work related off-site meetings. Employees working in customer-facing roles must adhere to and comply with customers’ (such as hospitals, physician offices, etc.) credentialing guidelines, which may require vaccination. As required by applicable law, Novartis will consider requests for reasonable accommodation for those unable to be vaccinated. This requirement is subject to applicable state and local laws and may not be applicable to employees working in certain jurisdictions. Please send accommodation requests to [email protected].
Regenerative Medicine - NIBR
San Diego, CA
Research & Development
Full Time
careers default image

Principal Scientist Regenerative Medicine in vivo bio NIBR La Jolla

Apply to Job Access Job Account