Jun 27, 2022

Job Description

6000! This is the number of associates in the Novartis Institutes for BioMedical Research (NIBR). This division is the innovation engine of Novartis, focusing on new technologies that have the potential to help produce therapeutic breakthroughs for patients. The Biologics Center (NBC) is housed within the Novartis Institutes for BioMedical Research (NIBR). NBC, in collaboration with the disease areas and other platform groups, builds the future biologics therapy pipeline of Novartis through the discovery and creation of new antibody, protein, nucleic acid and virus-based molecules.

We have an exciting opportunity for a Research Scientist to join our Biologics team in Cambridge in the preparation and advancement of novel antibodies and therapeutic proteins targeting multiple diseases and unmet medical needs. In this role, you will conduct and interpret a diverse set of biochemical and analytical experiments to produce and characterize novel biologics, including MS, SEC and other characterization techniques frequently used in the preclinical development of molecules.

What you’ll be doing:
Your responsibilities include, but are not limited to:
• Expression, purification and characterization of proteins and antibodies
• Carry out small to medium scale cell culture (up to 10L) for protein expression using transient and stable mammalian cells
• Purification of antibodies and proteins using various chromatographic methods with subsequent quality control
• Detailed documentation of results, present research updates and participate constructively in working project teams and at lab meetings

Diversity & Inclusion / EEO

The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Minimum Requirements

What you’ll bring to the role:
• B.S. in Biological Sciences, Chemistry or equivalent with 3+ years or M.S. with 1+ years experience in protein expression and purification, preferably including antibody technology.
• Well-organized, flexibility and ability to work under pressure
• Open and pro-active attitude; ability to understand and document heterogeneous data and to communicate effectively
• Experience in a biotech company or pharmaceutical industry is an asset
• Occasional lifting of 10 L

• Skilled with molecular biology techniques
• Experience in transient mammalian transfections and stable cell line development and FACS analysis is desirable
• Background in recombinant protein and antibody expression and purification as well as biophysical characterization of proteins and antibodies; experience with low endotoxin protein production is a plus Molecular biology knowledge and associated analysis tools is desirable
• Interest in chemical modification of proteins

Why Novartis
766 million lives were touched by Novartis medicines in 2021, and while we’re proud of this, we know there is so much more we could do to help improve and extend people’s lives.

We believe new insights, perspectives and ground-breaking solutions can be found at the intersection of medical science and digital innovation. That a diverse, equitable and inclusive environment inspires new ways of working.

We believe our potential can thrive and grow in an unbossed culture underpinned by integrity, curiosity and flexibility. And we can reinvent what's possible, when we collaborate with courage to aggressively and ambitiously tackle the world’s toughest medical challenges. Because the greatest risk in life, is the risk of never trying!
Imagine what you could do here at Novartis!

Commitment to Diversity & Inclusion:
Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve.

Accessibility and Reasonable Accommodations: The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please send an e-mail to [email protected] call +1 (877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.

While Novartis does not require vaccination at this time, for certain Novartis sites in the US all associates and candidates may be required to either upload an image of their COVID-19 vaccine card demonstrating proof of full vaccination for COVID-19 (or other similar evidence of vaccination) or proof of a negative COVID-19 test taken by the associate or candidate within the past seven days to enter any of our sites and/or customer office or healthcare facility, as well as prior to participating in other work related off-site meetings. Employees working in customer-facing roles must adhere to and comply with customers’ (such as hospitals, physician offices, etc.) credentialing guidelines, which may require vaccination. As required by applicable law, Novartis will consider requests for reasonable accommodation for those unable to be vaccinated. This requirement is subject to applicable state and local laws and may not be applicable to employees working in certain jurisdictions. Please send accommodation requests to [email protected].
Cambridge, MA
Research & Development
Full Time
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Research Scientist, Protein Production Biologics

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