345526BR
Jul 18, 2022
USA

Job Description

6000! That’s the number of associates in the Novartis Institutes for BioMedical Research (NIBR). This division is the innovation engine of Novartis, focusing on new technologies that have the potential to help produce therapeutic breakthroughs for patients. The NIBR Biologics Center (NBC) is housed within the Novartis Institutes for BioMedical Research (NIBR). NBC, in collaboration with the disease areas and other platform groups, builds the future biologics therapy pipeline of Novartis through the discovery and creation of new antibody, protein, nucleic acid and virus-based molecules.

We have an exciting opportunity for a Research Scientist to join our Biologics team in Cambridge in the preparation and advancement of novel antibodies and therapeutic proteins targeting multiple diseases and unmet medical needs. In this role, you will conduct and interpret a diverse set of biochemical and analytical experiments to produce and characterize novel biologics, including MS, SEC and other characterization techniques frequently used in the preclinical development of molecules.

What you’ll be doing:
• Cloning, expression, purification and characterization of proteins and antibodies
• Carry out small to medium scale cell culture (up to 10L) for protein expression using transient and stable mammalian cells
• Purification of antibodies and proteins using various chromatographic methods with subsequent quality control
• Stable cell line development
• Detailed documentation of results, present research updates and participate constructively in working project teams and at lab meetings

Diversity & Inclusion / EEO

The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Minimum Requirements

What you’ll bring to the role:
• B.S. in Biological Sciences, Chemistry or equivalent with 7+ years’ experience or M.S. with 5+ years’ experience in protein expression and purification, preferably including antibody technology.
• Well-organized and able to manage several projects simultaneously; high flexibility and ability to work under pressure
• Open and pro-active attitude; ability to understand and document heterogeneous data and to communicate effectively
• Experience in a biotech company or pharmaceutical industry is an asset
• Occasional lifting of 10 L

Desirable:
• Expertise in transient transfections and in stable cell line development and FACS analysis is desirable
• Background in recombinant protein and antibody expression and purification as well as biophysical characterization of proteins and antibodies; experience with low endotoxin protein production is a plus Molecular biology knowledge and associated analysis tools is desirable
• Interest in chemical modification of proteins

Commitment to Diversity & Inclusion:
Novartis embraces diversity, equal opportunity and inclusion. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Novartis is an equal opportunities employer and welcomes applications from all suitably qualified persons.
Accessibility and Reasonable Accommodations: The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please send an e-mail to [email protected] call +1 (877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.

Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to learn more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network

While Novartis does not require vaccination at this time, for certain Novartis sites in the US all associates and candidates may be required to either upload an image of their COVID-19 vaccine card demonstrating proof of full vaccination for COVID-19 (or other similar evidence of vaccination) or proof of a negative COVID-19 test taken by the associate or candidate within the past seven days to enter any of our sites and/or customer office or healthcare facility, as well as prior to participating in other work related off-site meetings. Employees working in customer-facing roles must adhere to and comply with customers’ (such as hospitals, physician offices, etc.) credentialing guidelines, which may require vaccination. As required by applicable law, Novartis will consider requests for reasonable accommodation for those unable to be vaccinated. This requirement is subject to applicable state and local laws and may not be applicable to employees working in certain jurisdictions. Please send accommodation requests to [email protected].
NIBR
BIOTHERAPEUTIC AND ANALYTICAL TECHNOLOGIES - NIBR
USA
Cambridge, MA
Research & Development
Full Time
Regular
No
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345526BR

Senior Scientist, Protein Production Biologics (BS/MS)

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