May 11, 2022

Job Description

$9.0 billion R&D spend to develop breakthrough medicines!

The Novartis Institutes for BioMedical Research (NIBR) Immuno-Oncology & Hematology (IOH) department is seeking a talented, highly motivated in vivo scientist to join our Cell and Gene Therapy group. The successful candidate will work with multi-disciplinary teams and play a key role in advancing IOH drug discovery projects as well as identifying novel therapeutic targets and approaches to benefit cancer patients with a focus on adoptive T cell therapies.

The successful candidate is expected to perform and excel in the following areas:

•Participate in the design and implementation of in vivo biology studies including subcutaneous and orthotopic cancer models to evaluate cellular therapy strategies, including efficacy, PK, PD and mechanism of action analyses.
•Perform ex vivo assays including immunology-based analysis and pharmaco-dynamic studies tailored to the therapy and target of interest, with an emphasis on flow cytometry analysis of tumor and other tissue samples.
•Document, analyze, and interpret experiments in a timely manner to inform project strategy and next steps.
•Present results within a multidisciplinary team environment.

Diversity & Inclusion / EEO

The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Minimum Requirements

What you'll bring to the role:

•B.A./B.S or M.S. in Pharmacology, Cell Biology or related field with 2+ years of industry or academic experience. The level of the position will be commensurate with experience.
•Proficiency with in vivo procedures in rodents, including multiple routes of dose administration (IP, PO, IV, SC), blood collection, dissection techniques, and necropsies
•Experience with xenografts and syngeneic models, in vivo assays for pharmacokinetic evaluations, flow analysis, and cell culture is preferred
•Knowledge of cancer biology, cell signaling and/or immunology is preferred
•Demonstrated ability to quickly learn and perform in new areas, implement new techniques and instrumentation, critical problem-solving, multi-tasking, and good organizational skills
•Meticulous laboratory approach, careful adherence to protocols and excellent lab notebook documentation
•Ability to work collaboratively in a team environment
•Strong analytical and computer skills
•Highly motivated, with a sense of urgency and flexibility
•Excellent interpersonal and communication skills

Why consider Novartis?

766 million lives were touched by Novartis medicines in 2021, and while we’re proud of this, we know there is so much more we could do to help improve and extend people’s lives.

We believe new insights, perspectives and ground-breaking solutions can be found at the intersection of medical science and digital innovation. That a diverse, equitable and inclusive environment inspires new ways of working.

We believe our potential can thrive and grow in an unbossed culture underpinned by integrity, curiosity and flexibility. And we can reinvent what's possible when we collaborate with courage to aggressively and ambitiously tackle the world’s toughest medical challenges. Because the greatest risk in life, is the risk of never trying!

Imagine what you could do here at Novartis!

What Novartis can offer you?

Yes, we offer exceptional benefits and competitive salaries. However, we can offer more.

Here you will:

• Get access to latest technologies and work with talented scientists
• Virtually learn and earn certificates from 190 universities around the world, all supported by Novartis through our partner Coursera.
• Get access to the Novartis Learning Institute which offers personal effectiveness, digital capability and language programs, as well as talent acceleration and leadership programs.

Commitment to Diversity & Inclusion:
Novartis is committed to building an outstanding, inclusive work environment and diverse team representative of the patients and communities we serve.

Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network
Cambridge, MA
Research & Development
Full Time
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In Vivo Scientist, Immuno-Oncology (BS/MS level)

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