345091BR
May 10, 2022
USA

Job Description

6000! This is the number of associates in the Novartis Institutes for BioMedical Research (NIBR). This division is the innovation engine of Novartis, focusing on new technologies that have the potential to help produce therapeutic breakthroughs for patients.

Novartis has an opportunity for an Executive Director Pharmacometrics to lead strategy for clinical development programs. In this role, you will drive and/or supervise pharmacometric strategy at development unit level in full clinical development programs, determine the strategic direction of the development and application of pharmacometrics methodologies at Novartis, be responsible for leading and optimizing the design and implementation of pharmacometric methodologies that help optimize drug development programs across the development organization, lead and optimize the contribution from drug development scientists by consulting with NIBR & Development and Global Medical Affairs partners. You are will possess a thorough understanding of clinical development and operational implications, and exhibit exemplary leadership skills.

What you’ll be doing:
Your responsibilities include, but are not limited to:
• Ensure PMX strategic contributions to, and influence the direction of, robust clinical development plans and their execution.
• Quickly step in and assume leadership in helping develop strategic quantitative frameworks for clinical programs in close collaboration with senior management/Development Units as required.
• Take leadership in representing pharmacometric science for clinical/submission teams and at regulatory interactions.
• Liaise with senior management to influence and negotiate on drug development innovation and clinical development plans with particular emphasis on MIDD strategies.
• Take a leadership role in collaboration with partners from other functions to ensure a coherent pharmacometrics contribution to the development strategy.
• As partner to senior clinical and scientific leadership, drive and shape strategic pharmacometrics input and excellence to drug development across multiple therapeutic or disease areas/indications.
• Anticipate Development Unit needs based on in-depth understanding of the relevant pharmacometrics issues.
• Propose or lead functional or cross-functional initiatives requiring coordination of diverse of team members.
• Independently represent PMX in due-diligence teams for high-complexity in-licensing opportunities and drive toward steps required to implement a possible deal.
• Mentor and develop next generation pharmacometricians

Diversity & Inclusion / EEO

The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Minimum Requirements

What you’ll bring to the role:
• Ph.D. in pharmacology, biology, engineering, mathematics, statistics, computational science, or a field with significant modeling-related content (or equivalent) with 12+ years of experience in positions with ever increasing relevant responsibilities; 10+ years in applying, innovating, and mentoring model based methods in pre-clinical and clinical drug development.
• Expert knowledge and evidence of hands-on experience in the application of pharmacometrics methods to drug development
• Evidence of consulting skill in the drug development context, i.e. within project teams and management boards; experience interacting with regulatory agencies.
• Clinical, pharmacological and therapeutic knowledge in one or more disease areas
• Proven expert scientific leadership skills demonstrated in facilitating and optimizing the clinical development strategy.
• Excellent record of leading the interface to regulatory agencies.
• Expert knowledge of drug development and HA guidelines relevant to all areas of pharmacometrics in clinical drug development.
• Excellent communication and presentation skills and in particular the ability to effectively represent pharmacometrics issues to a wide range of target audiences.
• Strong leadership and mentoring skills. Drives and motivates teams and peers.

Location
This position can be based out of East Hanover NJ, Cambridge, MA or Basel, Switzerland

Why Novartis
766 million lives were touched by Novartis medicines in 2021, and while we’re proud of this, we know there is so much more we could do to help improve and extend people’s lives.

We believe our potential can thrive and grow in an unbossed culture underpinned by integrity, curiosity and flexibility. And we can reinvent what's possible, when we collaborate with courage to aggressively and ambitiously tackle the world’s toughest medical challenges. Because the greatest risk in life, is the risk of never trying!

Imagine what you could do here at Novartis!

Commitment to Diversity & Inclusion:
Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve.

Accessibility and Reasonable Accommodations: The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please send an e-mail to [email protected] call +1 (877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.

While Novartis does not require vaccination at this time, for certain Novartis sites in the US all associates and candidates may be required to either upload an image of their COVID-19 vaccine card demonstrating proof of full vaccination for COVID-19 (or other similar evidence of vaccination) or proof of a negative COVID-19 test taken by the associate or candidate within the past seven days to enter any of our sites and/or customer office or healthcare facility, as well as prior to participating in other work related off-site meetings. Employees working in customer-facing roles must adhere to and comply with customers’ (such as hospitals, physician offices, etc.) credentialing guidelines, which may require vaccination. As required by applicable law, Novartis will consider requests for reasonable accommodation for those unable to be vaccinated. This requirement is subject to applicable state and local laws and may not be applicable to employees working in certain jurisdictions. Please send accommodation requests to [email protected].
Global Drug Development
CD&A GDD
USA
East Hanover, NJ
Switzerland
Research & Development
Full Time
Regular
No
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345091BR

Executive Director Pharmacometrics

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