May 10, 2022

Job Description

85% of the proteome is currently undrugged. Join our effort to tackle a longstanding challenge in early drug discovery by identifying covalent small molecules that modulate the activity of these so far undrugged targets and pathways to positively impact human health.

The Chemical Biology and Therapeutics department is seeking a highly motivated and adaptable candidate for a Scientist position to expand its current effort in chemical proteomics and covalent drug discovery.

Experience with protein/peptide analysis and excellent quantitative analytical skills using quantitative mass spectrometry methods (e.g. TMT, label-free) are required in addition to familiarity with latest chemical proteomics methodology, mass spectrometry equipment, and approaches.

The successful candidate will have demonstrated abilities in application and development of high-throughput proteomics and quantitative mass spectrometry.

The position requires the ability to independently design quantitative (chemo)proteomics experiments, operate and troubleshoot automation and data acquisition equipment as well as optimize existing workflows.

Effective self-management is required for success in a highly dynamic team environment with sometimes rapidly changing objectives.

Applicants require good organizational and communication skills together with the ability to interpret and present results and scientific information critically and objectively.

Primary responsibilities include:
• Execution and automation of proteomic sample preparation workflows
• Operation, maintenance, and troubleshooting of state-of-the art mass spectrometry and associated equipment
• Analysis of quantitative MS data using equipment vendor and 3rd party software
• Report generation and presentation of results and interpretations

Diversity & Inclusion / EEO

The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Minimum Requirements

What you will bring to the role:

Education: B.S., M.S., or Ph.D. in the life sciences or related field with a minimum of 5 years of relevant experience.
• Familiarity with Orbitrap mass spectrometers and nano-LC equipment
• Ability to execute standard proteomic laboratory techniques and practices
• Knowledge in programming and operation of liquid-handling equipment
• Ability to analyze, interpret, and summarize results independently
• Additional experience with timsTOF Pro analyzers is considered a plus

Why consider Novartis?

We believe the answers are found when curious, courageous and collaborative people like you are brought together in an inspiring environment. Where you’re given opportunities to explore the power of digital and data. Where you’re empowered to risk failure by taking smart risks, and where you’re surrounded by people who share your determination to tackle the world’s toughest medical challenges.

We are Novartis. Join us and help us reimagine medicine.

While Novartis does not require vaccination at this time, for certain Novartis sites in the US all associates and candidates may be required to either upload an image of their COVID-19 vaccine card demonstrating proof of full vaccination for COVID-19 (or other similar evidence of vaccination) or proof of a negative COVID-19 test taken by the associate or candidate within the past seven days to enter any of our sites and/or customer office or healthcare facility, as well as prior to participating in other work related off-site meetings. Employees working in customer-facing roles must adhere to and comply with customers’ (such as hospitals, physician offices, etc.) credentialing guidelines, which may require vaccination. As required by applicable law, Novartis will consider requests for reasonable accommodation for those unable to be vaccinated. This requirement is subject to applicable state and local laws and may not be applicable to employees working in certain jurisdictions. Please send accommodation requests to [email protected]
San Diego, CA
Research & Development
Full Time
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Chemoproteomics Sci. Mass spectrometry instrumentation & automation

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