May 09, 2022

Job Description

4 FDA approved drugs, 15+ clinical candidates, with over 500+ patents and peer-reviewed publications! Impressive and important numbers. NIBR San Diego is where cutting-edge research and technology improves lives. The Novartis Institutes for Biomedical Research (NIBR San Diego) has been on the frontline of innovative drug discovery for over 21 years.

Join us to make a difference in medicine for the next twenty years!

The global discovery chemistry department (GDC) is looking for a highly motivated scientist skilled in synthetic chemistry, purification technology, and analytical chemistry to support programs in the thematic areas of cancer research, regenerative medicine, covalent drug discovery, and siRNA. The successful candidate will work as part of a multi-disciplinary team along with other drug discovery disciplines to craft new synthetic molecules that will drive the future of medicine.

Primary responsibilities:
Work as part of a small team focused on utilizing novel methodologies for batch and library synthesis of small-molecule drug candidates, to support and advance drug discovery projects
Carry out multi-step, batch, library and flow chemistry syntheses of small molecules, utilizing modern automated purification and analytical equipment, and advanced data handling approaches. This includes identifying and solving synthetic issues to drive highest quality compound production.
Support novel compound synthesis for structure activity relationship (SAR) analysis on biological assays and follow up with new hypotheses and experiments.
Communicate and present scientific and technical work to colleagues in small and large group settings
Collaborate with scientific teams across the San Diego and global Novartis sites
Adhere to laboratory safety policies and practices including the use of electronic record keeping


Diversity & Inclusion / EEO

The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Minimum Requirements

Minimum Requirements:
• BS degree in organic chemistry

• Knowledge of modern organic synthetic methods with a strong basis in functional group transformations and cross couplings methods, with medicinal chemistry knowledge a plus

• Skilled in common small molecule purification and analytical techniques including normal and reverse phase chromatography and LCMS methods; affinity for instrumentation and library synthesis

• Strong problem solving and communication skills with a collaborative team- oriented mindset

Desired Qualifications:

• Master’s degree in organic chemistry

• 2+ years of industry experience

Why Novartis?
799 million. That’s how many lives our products touch. And while we’re proud of that fact, in this world of digital and technological transformation, we must also ask ourselves this: how can we continue to improve and extend even more people’s lives?

We believe the answers are found when curious, courageous and collaborative people like you are brought together in an inspiring environment. Where you’re given opportunities to explore the power of digital and data. Where you’re empowered to risk failure by taking smart risks, and where you’re surrounded by people who share your determination to tackle the world’s toughest medical challenges.

We are Novartis. Join us and help us reimagine medicine.
Global Discovery Chemistry
San Diego, CA
Research & Development
Full Time
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Research Scientist - Organic Chemist

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