344776BR
Jun 03, 2022
Switzerland

Job Description

1 out of 10 people are suffering from immunological diseases. The Autoimmunity, Transplantation & Inflammation (ATI) Disease Area at the Novartis Institutes for Biomedical Research (NIBR) is investing in the discovery of novel and transformative therapies to improve the life of affected patients. As part of this effort, ATI is seeking an innovative and highly motivated Principal Scientist or Senior Principal Scientist to initiate and guide research approaches in the area of Immune Tolerance.

You will be responsible for leading a state-of-the-art laboratory of experienced scientists to discover and develop novel therapies aiming at restoring tolerance in various autoimmune and inflammatory diseases. This will include the use of in vitro assays and in vivo models to evaluate innovative therapeutic approaches with potential for long-term impact on the disease course.
• Contribute to and/or lead early drug discovery projects within multidisciplinary teams up to clinical proof-of-concept studies in patients
• Define and execute on innovative scientific strategies, test novel disease-relevant hypotheses and develop transformative therapies
• Closely collaborate with scientists, clinicians, and technology experts across different departments in the global organization.

Diversity & Inclusion / EEO

Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve.

Minimum Requirements

What you will bring to the role:

• PhD degree in immunology, autoimmunity, immuno-oncology or related field
• In-depth knowledge of human and mouse immunology, mechanisms of tolerance induction and cell populations with immunoregulatory properties
• Experience in cutting-edge novel therapeutic approaches (e.g. gene-, RNA/DNA- or cell-therapy, complex biologics modalities, etc)
• Significant scientific accomplishments and successful collaborations documented by publications in high-impact journals
• Excellent organization, communication, presentation and analytical skills

Desirable requirements:

• PhD + a minimum of 5 years of relevant research experience in an academic setting and/or in the pharmaceutical/biotech sector
• Proven experience in independently working on projects dissecting immunological pathways in health and disease, or evaluating innovative therapeutic strategies for efficacious and durable treatment of immune-mediated pathologies

769 million. That’s how many lives our products touched in 2020. And while we’re proud of that fact, in this world of digital and technological transformation, we must also ask ourselves this: how can we continue to improve and extend even more people’s lives?

We believe the answers are found when curious, courageous and collaborative people like you are brought together in an inspiring environment. Where you’re given opportunities to explore the power of new technologies. Where you’re empowered to risk failure by taking smart risks, and where you’re surrounded by people who share your determination to tackle the world’s toughest medical challenges.

We are Novartis. Join us and help us reimagine medicine.

* Some restrictions on flexible working options may apply and will be discussed during interview if applicable.
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If this role is not suitable to your experience or career goals but you wish to stay connected to learn more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network
NIBR
AUTO/TRANS/INFL - NIBR
Switzerland
Basel
Research & Development
Full Time
Regular
No
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344776BR

Lab Head - Novel Therapeutic Modalities for Immune Tolerance 80-100%*

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