May 03, 2022

Job Description

12,000. The number of associates worldwide working together to reimagine medicine!

The Global Drug Development (GDD) organization oversees the development of new medicines discovered by our researchers and partners. We transform the lives of people by developing innovative and life-changing medicines.

The Senior Expert, Science & Technology, is responsible as a technical lead in gene therapy
downstream process development, designing and executing downstream process development activities,
as well as performing downstream process operations at both small scale and large scale to support
pipeline research and pre-clinical studies.

Your responsibilities will include, but are not limited to:

• Advances complex downstream process development efforts as a technical lead within a cross-functional team across sites.
• Independently designs and executes gene therapy downstream process development studies.
• Performs experiments at both large-scale and small-scale to support pre-clinical, clinical and commercial programs. Ensures these experiments are done in a timely fashion with high quality.
• Stays current with the latest scientific and engineering developments in the field.
• Leverages strong understanding of biologics downstream process to evaluate and introduces new technologies and innovative ideas related to downstream process development.
• Analyzes and interprets experimental data from process studies with strong statistical mindset. Makes decisions based on statistically sound conclusions.
•Presents study results internally and externally in a cross-functional setting.
• Independently authors technical reports of studies of process development activities and laboratory experiments, such as development report, study report, investigational summary report, etc.
• Collaborates with cross-functional groups to advance pipeline programs. Provides support for regulatory filings and author sections in IND filings.
•Leads and mentors technical team fostering innovative and collaborative culture.
• Communicates effectively with diverse teams to coordinate lab activities and manage resources.

Diversity & Inclusion / EEO

The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Minimum Requirements

What you'll bring to the role:

• Bachelor's, biological sciences, pharmaceutical sciences or related technical field with 8 years relevant experience or Master's with 6 or PHD with 4.
• Comprehensive experience with a variety of biopharmaceutical purification processes such as chromatographic separation, depth filtration, precipitation & flocculation, tangential flow filtration, adventitious viral clearance, ultracentrifugation, and impurity clearance.
• Proficient in statistical analysis principles and approaches. Working knowledge and experience with Design of Experiment (DoE).
• Ability to analyze data to make date-driven decisions and further progress development strategies.
• Proven team leader with previous experience of effectively leading technical group.
• Innovative with a continuous improvement mindset.
• Good communication skills with project management experience in cross-functional setting.

Why Novartis?
766 million lives were touched by Novartis medicines in 2021, and while we’re proud of this, we know there is so much more we could do to help improve and extend people’s lives.
We believe new insights, perspectives and ground-breaking solutions can be found at the intersection of medical science and digital innovation. That a diverse, equitable and inclusive environment inspires new ways of working. We believe our potential can thrive and grow in an unbossed culture underpinned by integrity, curiosity and flexibility. And we can reinvent what's possible, when we collaborate with courage to aggressively and ambitiously tackle the world’s toughest medical challenges. Because the greatest risk in life, is the risk of never trying!
Imagine what you could do here at Novartis!

Please note this job description is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities that are required of the employee for this job. Duties, responsibilities and activities may change at any time with or without notice.

Accessibility and reasonable accommodations
The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please send an e-mail to [email protected] call +1 (877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.
Global Drug Development
Durham, NC
Research & Development
Full Time
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Senior Expert Science & Technology (Downstream Process Development)

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